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The map label for this gene is rpiA [H]

Identifier: 157372158

GI number: 157372158

Start: 4347888

End: 4348607

Strand: Reverse

Name: rpiA [H]

Synonym: Spro_3924

Alternate gene names: 157372158

Gene position: 4348607-4347888 (Counterclockwise)

Preceding gene: 157372160

Following gene: 157372157

Centisome position: 79.81

GC content: 53.89

Gene sequence:

>720_bases
GTGAAAAATAGCGATTTACCCTATAATACGCACACGTTTTCGTACAGAGGCAATGGACATATTATGACGCAGGATGAACT
GAAAAAAGCGGTTGGCTGGGCAGCACTGGATTACGTTACCCCGGGCACCATCGTTGGGGTCGGCACTGGCTCGACTGCCG
CCCATTTTATTGACGCGCTCGGCTCGATCAAGCACCAGATCGAAGGGGCGGTGTCCAGCTCTGACGCCTCTACCGCCAAG
CTGAAAAGCCTCGGTATCCACGTTTTCGACAGCAATGAAGTGGATTCACTGGATATTTATGTCGACGGCGCGGATGAAAT
CAACCGCCATATGCAGATGATCAAAGGCGGCGGCGCTGCGCTGACGCGTGAAAAAATCATTGCCGCTATCGCGCGCAAAT
TTATCTGTATTGTCGATTCCAGCAAACAGGTCGATGTGTTGGGTAAATTCCCTCTGCCGGTAGAAGTCATCCCGATGGCA
CGTTCTTACGTAGCGCGTGAGCTGGTCAAGCTGGGCGGGCTGCCGGAGTATCGTCAGAATGTCCTGACCGATAACGGCAA
CGTGATCCTCGATGTGCATAACCTGAGTATCATGGACGCCATTGCGCTGGAAAACAAAATCAACGGCATCGCCGGTGTGG
TGACCGTGGGTCTGTTCGCCAACCGGGGTGCCGATGTGGCGCTGGTAGGTACGCCTGACGGCGTGAAGGTTGTCGAATAA

Upstream 100 bases:

>100_bases
GCCACATCTCTGGTGTATTACAGGTGGAAAATCACTGGGCCATCTTGCCGCACCGCGCCTAAAAATGCGGCCTGGCGTGA
AGAAGTGTGATCCTGCCTAA

Downstream 100 bases:

>100_bases
TGTAGTGCCGCTACAGGTATGCGGTCTTGGATCCCACCAGGCCGCATAATTCACTGGTTAAAATATCTTTTATTAAAAGC
GTCAAATTTGGTGACATATG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKNSDLPYNTHTFSYRGNGHIMTQDELKKAVGWAALDYVTPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAK
LKSLGIHVFDSNEVDSLDIYVDGADEINRHMQMIKGGGAALTREKIIAAIARKFICIVDSSKQVDVLGKFPLPVEVIPMA
RSYVARELVKLGGLPEYRQNVLTDNGNVILDVHNLSIMDAIALENKINGIAGVVTVGLFANRGADVALVGTPDGVKVVE

Sequences:

>Translated_239_residues
MKNSDLPYNTHTFSYRGNGHIMTQDELKKAVGWAALDYVTPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAK
LKSLGIHVFDSNEVDSLDIYVDGADEINRHMQMIKGGGAALTREKIIAAIARKFICIVDSSKQVDVLGKFPLPVEVIPMA
RSYVARELVKLGGLPEYRQNVLTDNGNVILDVHNLSIMDAIALENKINGIAGVVTVGLFANRGADVALVGTPDGVKVVE
>Mature_239_residues
MKNSDLPYNTHTFSYRGNGHIMTQDELKKAVGWAALDYVTPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAK
LKSLGIHVFDSNEVDSLDIYVDGADEINRHMQMIKGGGAALTREKIIAAIARKFICIVDSSKQVDVLGKFPLPVEVIPMA
RSYVARELVKLGGLPEYRQNVLTDNGNVILDVHNLSIMDAIALENKINGIAGVVTVGLFANRGADVALVGTPDGVKVVE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=35.2678571428571, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=85.2534562211981, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17551758, Length=214, Percent_Identity=34.5794392523364, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=240, Percent_Identity=29.5833333333333, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281364072, Length=203, Percent_Identity=32.512315270936, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 25412; Mature: 25412

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSDLPYNTHTFSYRGNGHIMTQDELKKAVGWAALDYVTPGTIVGVGTGSTAAHFIDAL
CCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
GSIKHQIEGAVSSSDASTAKLKSLGIHVFDSNEVDSLDIYVDGADEINRHMQMIKGGGAA
HHHHHHHHCCCCCCCCHHHHHHHCEEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCCCH
LTREKIIAAIARKFICIVDSSKQVDVLGKFPLPVEVIPMARSYVARELVKLGGLPEYRQN
HHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHH
VLTDNGNVILDVHNLSIMDAIALENKINGIAGVVTVGLFANRGADVALVGTPDGVKVVE
HCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECC
>Mature Secondary Structure
MKNSDLPYNTHTFSYRGNGHIMTQDELKKAVGWAALDYVTPGTIVGVGTGSTAAHFIDAL
CCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
GSIKHQIEGAVSSSDASTAKLKSLGIHVFDSNEVDSLDIYVDGADEINRHMQMIKGGGAA
HHHHHHHHCCCCCCCCHHHHHHHCEEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCCCH
LTREKIIAAIARKFICIVDSSKQVDVLGKFPLPVEVIPMARSYVARELVKLGGLPEYRQN
HHHHHHHHHHHHHEEEEECCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHH
VLTDNGNVILDVHNLSIMDAIALENKINGIAGVVTVGLFANRGADVALVGTPDGVKVVE
HCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA