Click here to switch to the map view.

The map label for this gene is ltrA [H]

Identifier: 157372091

GI number: 157372091

Start: 4268280

End: 4269230

Strand: Reverse

Name: ltrA [H]

Synonym: Spro_3856

Alternate gene names: 157372091

Gene position: 4269230-4268280 (Counterclockwise)

Preceding gene: 157372093

Following gene: 157372087

Centisome position: 78.35

GC content: 60.36

Gene sequence:

>951_bases
ATGAAAAACCCAAAAATAGAAACCCTGTGGACCCATTTGCACTGGCTCACCGTGCTGGCCGAGCAGGGCAGTTTTACCCG
TGCGGCGGAGCGGCTGGATGTCAGCAAAGCGGCGATGAGCCAAAAAATCAAAGAGATTGAAACCTTGGCCGGGGTGCCGC
TGGTGCAACGCACGACGCGCAGCGTCAGACTGACCGATGCCGGGCTGCGACTGGTGGAGGAACTGCGCCAGCCTTTCGCG
CAGATAAAGCAGAGTTTCTCCGGCATTTGCGATTCGGCCGGGCCGCTGCGTGGTTCGGTACGGGTGACGGCGCCGGTGGC
GTTTGCCCGCCAGCAGCTGGTGCCACGTATTACCGGCTTTCTGCGTGCTAATCCGGAGGTGCGGTTGCAGCTTGAGGTGT
CCGACCGGCTGGTGTCGTTAACCAGCGAAGGGTTTGATTTGGCGATCCGCCACAGTGACAACCTGCCTGATACCCATGTT
GCCTGGCGGCTGTGCCAGACCGAAACCTTGGCGGTGGCGTCGGCAGACTACGTGAAACGGCACGGCATGCCGGTTTCACC
GGCCGATCTGCAACGGCATCAGTGTCTTTATTATCCCCGCAGCAGTGAATCCCCGAGCTGGAGCTTTGTCGCCAAACGGG
CAGCAGAGGGCAAGACAGAAAAGATTCGGGTGCCGGTCAGCGGCCCGTTTGCCACCAACAACAGCGAGTCGATACGTGAT
GCGGCAGCGGAAGGTTTGGGCATTGCCCTGTTGCCTGACTTTAGCGCGCAGCAGGCATTGGCAGACGGCAGATTGATCGA
GGTATTACCGGCCTGGCGGCCGATAGATGCCTTTGCTGACAGCCTTTATGTGGTACGCCCTTATGCGCCCCAGGTCTCGC
GAGCGGTGGCGGAGTTCAGCCGTTATCTGCGCAGTGCCTTTGCCGAGGGGTTTTCGTCTGCCGGGTGCTGA

Upstream 100 bases:

>100_bases
GCGAGTTATCTTCGCCTTTGAGAACCCATCTTAGCCAAGCGGCGGTGTGGGAAGAAGCGCTATACTTGAACTCATTGTTT
ATATAAATGAACAGTCGACG

Downstream 100 bases:

>100_bases
ATTGCCCGCGTTACCCCCCTCCAAGGCTGGCGCAATGGTAACGCTAATTATAAGAACAATGTGATTAACGCAGCCCCTGG
ACCAGTGAGTCGGCGCTGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKNPKIETLWTHLHWLTVLAEQGSFTRAAERLDVSKAAMSQKIKEIETLAGVPLVQRTTRSVRLTDAGLRLVEELRQPFA
QIKQSFSGICDSAGPLRGSVRVTAPVAFARQQLVPRITGFLRANPEVRLQLEVSDRLVSLTSEGFDLAIRHSDNLPDTHV
AWRLCQTETLAVASADYVKRHGMPVSPADLQRHQCLYYPRSSESPSWSFVAKRAAEGKTEKIRVPVSGPFATNNSESIRD
AAAEGLGIALLPDFSAQQALADGRLIEVLPAWRPIDAFADSLYVVRPYAPQVSRAVAEFSRYLRSAFAEGFSSAGC

Sequences:

>Translated_316_residues
MKNPKIETLWTHLHWLTVLAEQGSFTRAAERLDVSKAAMSQKIKEIETLAGVPLVQRTTRSVRLTDAGLRLVEELRQPFA
QIKQSFSGICDSAGPLRGSVRVTAPVAFARQQLVPRITGFLRANPEVRLQLEVSDRLVSLTSEGFDLAIRHSDNLPDTHV
AWRLCQTETLAVASADYVKRHGMPVSPADLQRHQCLYYPRSSESPSWSFVAKRAAEGKTEKIRVPVSGPFATNNSESIRD
AAAEGLGIALLPDFSAQQALADGRLIEVLPAWRPIDAFADSLYVVRPYAPQVSRAVAEFSRYLRSAFAEGFSSAGC
>Mature_316_residues
MKNPKIETLWTHLHWLTVLAEQGSFTRAAERLDVSKAAMSQKIKEIETLAGVPLVQRTTRSVRLTDAGLRLVEELRQPFA
QIKQSFSGICDSAGPLRGSVRVTAPVAFARQQLVPRITGFLRANPEVRLQLEVSDRLVSLTSEGFDLAIRHSDNLPDTHV
AWRLCQTETLAVASADYVKRHGMPVSPADLQRHQCLYYPRSSESPSWSFVAKRAAEGKTEKIRVPVSGPFATNNSESIRD
AAAEGLGIALLPDFSAQQALADGRLIEVLPAWRPIDAFADSLYVVRPYAPQVSRAVAEFSRYLRSAFAEGFSSAGC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=306, Percent_Identity=32.3529411764706, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=32.7645051194539, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI87081978, Length=305, Percent_Identity=30.4918032786885, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789440, Length=261, Percent_Identity=29.1187739463602, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786401, Length=272, Percent_Identity=30.5147058823529, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787128, Length=256, Percent_Identity=30.46875, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786448, Length=248, Percent_Identity=29.8387096774194, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788706, Length=259, Percent_Identity=27.4131274131274, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789173, Length=248, Percent_Identity=27.8225806451613, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790011, Length=321, Percent_Identity=23.6760124610592, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789639, Length=264, Percent_Identity=26.8939393939394, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=124, Percent_Identity=36.2903225806452, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786713, Length=271, Percent_Identity=27.6752767527675, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787879, Length=306, Percent_Identity=23.5294117647059, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34813; Mature: 34813

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNPKIETLWTHLHWLTVLAEQGSFTRAAERLDVSKAAMSQKIKEIETLAGVPLVQRTTR
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
SVRLTDAGLRLVEELRQPFAQIKQSFSGICDSAGPLRGSVRVTAPVAFARQQLVPRITGF
EEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LRANPEVRLQLEVSDRLVSLTSEGFDLAIRHSDNLPDTHVAWRLCQTETLAVASADYVKR
HCCCCCEEEEEEECHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHH
HGMPVSPADLQRHQCLYYPRSSESPSWSFVAKRAAEGKTEKIRVPVSGPFATNNSESIRD
CCCCCCHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHH
AAAEGLGIALLPDFSAQQALADGRLIEVLPAWRPIDAFADSLYVVRPYAPQVSRAVAEFS
HHHCCCCEEEECCCCHHHHHHCCCEEEECCCCCCHHHHHCCEEEEECCCHHHHHHHHHHH
RYLRSAFAEGFSSAGC
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNPKIETLWTHLHWLTVLAEQGSFTRAAERLDVSKAAMSQKIKEIETLAGVPLVQRTTR
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
SVRLTDAGLRLVEELRQPFAQIKQSFSGICDSAGPLRGSVRVTAPVAFARQQLVPRITGF
EEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LRANPEVRLQLEVSDRLVSLTSEGFDLAIRHSDNLPDTHVAWRLCQTETLAVASADYVKR
HCCCCCEEEEEEECHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHH
HGMPVSPADLQRHQCLYYPRSSESPSWSFVAKRAAEGKTEKIRVPVSGPFATNNSESIRD
CCCCCCHHHHCCCEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHH
AAAEGLGIALLPDFSAQQALADGRLIEVLPAWRPIDAFADSLYVVRPYAPQVSRAVAEFS
HHHCCCCEEEECCCCHHHHHHCCCEEEECCCCCCHHHHHCCEEEEECCCHHHHHHHHHHH
RYLRSAFAEGFSSAGC
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]