Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 157372048

GI number: 157372048

Start: 4214035

End: 4215900

Strand: Reverse

Name: recD [H]

Synonym: Spro_3813

Alternate gene names: 157372048

Gene position: 4215900-4214035 (Counterclockwise)

Preceding gene: 157372049

Following gene: 157372046

Centisome position: 77.37

GC content: 61.25

Gene sequence:

>1866_bases
ATGATCGCTCTACTGGAACAGGCGCAAGCGCTTGGCGTGTTACGTCCACTAGATTTGCAGTTCGCCAGCGTAGTCGCTGG
AGCGGATGAGCCTGAGATACTGTTGGCTGCCGCCTGCCTCAGTGCGGAGGCTGGCGCGGGTCACGTTTGCCTGATGCTGG
AGCAACTGCTGCCGGAAAACCTATTTGACGGACGTCAGCCGGAGCTGGCGCAGGCCGTGTGGTTGGCGGCAGGGCAGTTG
GATGTGGCCGGTTGGCAACGGCGGCTGTCGGCCAGTGCGGCGGTGAGCGACGGCAGCACTGCGACGCCGATGGTGTTACA
ACCACAGCGCTTGTATCTGCAGCGCATGTGGCAGAACGAGGGGGAGGTTGCCGCCTTTATCCGTGGTGACAGTATCAGCA
GCGACAGTCTGCCTCAGGCGGTTGAAGAGGCCGACCTGCGCACCATTCTCGACCAATTATTTGGTGAGGCGACCGATGAA
CCCGACTGGCAAAAAATTGCTGCCGCGGTGGCCGCTACGCGACGTATTGCAGTGATTTCGGGCGGACCGGGCACCGGTAA
GACCACCACGGTCGCCAAATTGTTGGCGGCGCTGGTGCAGCTCGATGAAGGGCGACGTTTACGCATCCAACTGGCGGCGC
CTACCGGTAAAGCGGCGGCGCGTTTAACCGAATCGTTAGGCAGTGCCGGCAAACAATTGGCGCTAACCCCGGAGCAGCGT
GCGTTGTTCCCTACCGAGGCCTCCACGTTGCATCGCCTGCTGGGCGCTCAGCCCAACAGTCAGCGTATGCGTTATCACAG
TGGCAACCGGCTGCATCTGGACGTGCTGGTAGTTGATGAGGCCTCTATGGTCGACCTGCCTATGATGGCGCGTTTGATTG
CCGCCTTGCCCACTCAGGCACGGGTGATCTTCCTGGGCGATCGCGATCAACTGGCTTCGGTGGAGGCCGGGGCGGTACTG
GGAGATATTTGCCGCTTTGCCGAACAAGGTTACAGCGTGGCGCGGGCGGAGCAACTTTCGCGGCTGACCGGCTGCCGGCT
ACAGGGGCAAACTGCCCAGGCGGAAGCTGCGGTGCGCGACAGTCTGTGCCTGCTGCGTAAAAGCTACCGTTTTGATGCCA
ATTCGGGTATTGGTCAATTGGCCTTTGCCGTGAACGCCGGTGATGGCAAGCGGGCAATGGCGGCGCTCAGCGGCAGTTTC
GCTGACGTTAGCGGTTATCCACTGGCGGAAACGCAGGACTATCAGGCGTTGTTGGATGCCTGCGTGGCGGGTTACCGTGA
TTATCTGCGGCTGGTGGGTGAAGGGGCGGACGCAGTGGCGGTGTTGGCGGCGTTCGGTCATTTCCAGGTGCTGTGCGCGC
TGCGCGAGGGGCCTTTCGGCATCGCCGGGTTAAATGACCGCATTGAGACGGGGCTGCAACGTGCCGGTCTAATCCAGCGT
AAGCCGGGAGCCGCTGGGCGTTGGTATTCCGGCCGTCCGGTGATGATTGGTCGCAATGACAGCGCTCTGGGGCTGTTTAA
CGGCGATATTGGCATTGCCTTGCGGGACGAGAGCGGCGAACTACGTGTTCACTTTCAACTGCCGGACGGCAGCATCAAGT
CGGTGCAGCCGAGCCGTTTACCGGCGCATGAAACCGCTTATGCGATGACGGTGCATAAATCACAAGGCTCGGAGTTTGAC
CATACGGTACTGGTGTTGCCCAATCATTTCCTGCCGGTGCTGACCCGTGAACTGGTGTACACCGCGATCACCCGCGCTCG
CAGGCAGCTTTCGCTGTACGCCATCGATGCGGTTTTGATGCGGGCGATCCGCACTCCGACCCAGCGCCGTAGCGGATTGG
CGGAGCGGTTGCAGCTCAAGGCTTAA

Upstream 100 bases:

>100_bases
ATCCGGGCAACGGCATTTTTGCCTGCCGTCCGCAGGAGCAATTGGTGGAAGGCATGGATTTGTTATTCAGCGGTAAAACC
GCTGCGGTGGAGGATGCATC

Downstream 100 bases:

>100_bases
GTGCCCATGGGCGCAGCACGCTGCGCCCGCCAACCATTACAGATCCGCCAGCAAAATCTTGGAACGGCGTTGGTAGTTGT
ACAGCGCCTGTTTCTCAACC

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MIALLEQAQALGVLRPLDLQFASVVAGADEPEILLAAACLSAEAGAGHVCLMLEQLLPENLFDGRQPELAQAVWLAAGQL
DVAGWQRRLSASAAVSDGSTATPMVLQPQRLYLQRMWQNEGEVAAFIRGDSISSDSLPQAVEEADLRTILDQLFGEATDE
PDWQKIAAAVAATRRIAVISGGPGTGKTTTVAKLLAALVQLDEGRRLRIQLAAPTGKAAARLTESLGSAGKQLALTPEQR
ALFPTEASTLHRLLGAQPNSQRMRYHSGNRLHLDVLVVDEASMVDLPMMARLIAALPTQARVIFLGDRDQLASVEAGAVL
GDICRFAEQGYSVARAEQLSRLTGCRLQGQTAQAEAAVRDSLCLLRKSYRFDANSGIGQLAFAVNAGDGKRAMAALSGSF
ADVSGYPLAETQDYQALLDACVAGYRDYLRLVGEGADAVAVLAAFGHFQVLCALREGPFGIAGLNDRIETGLQRAGLIQR
KPGAAGRWYSGRPVMIGRNDSALGLFNGDIGIALRDESGELRVHFQLPDGSIKSVQPSRLPAHETAYAMTVHKSQGSEFD
HTVLVLPNHFLPVLTRELVYTAITRARRQLSLYAIDAVLMRAIRTPTQRRSGLAERLQLKA

Sequences:

>Translated_621_residues
MIALLEQAQALGVLRPLDLQFASVVAGADEPEILLAAACLSAEAGAGHVCLMLEQLLPENLFDGRQPELAQAVWLAAGQL
DVAGWQRRLSASAAVSDGSTATPMVLQPQRLYLQRMWQNEGEVAAFIRGDSISSDSLPQAVEEADLRTILDQLFGEATDE
PDWQKIAAAVAATRRIAVISGGPGTGKTTTVAKLLAALVQLDEGRRLRIQLAAPTGKAAARLTESLGSAGKQLALTPEQR
ALFPTEASTLHRLLGAQPNSQRMRYHSGNRLHLDVLVVDEASMVDLPMMARLIAALPTQARVIFLGDRDQLASVEAGAVL
GDICRFAEQGYSVARAEQLSRLTGCRLQGQTAQAEAAVRDSLCLLRKSYRFDANSGIGQLAFAVNAGDGKRAMAALSGSF
ADVSGYPLAETQDYQALLDACVAGYRDYLRLVGEGADAVAVLAAFGHFQVLCALREGPFGIAGLNDRIETGLQRAGLIQR
KPGAAGRWYSGRPVMIGRNDSALGLFNGDIGIALRDESGELRVHFQLPDGSIKSVQPSRLPAHETAYAMTVHKSQGSEFD
HTVLVLPNHFLPVLTRELVYTAITRARRQLSLYAIDAVLMRAIRTPTQRRSGLAERLQLKA
>Mature_621_residues
MIALLEQAQALGVLRPLDLQFASVVAGADEPEILLAAACLSAEAGAGHVCLMLEQLLPENLFDGRQPELAQAVWLAAGQL
DVAGWQRRLSASAAVSDGSTATPMVLQPQRLYLQRMWQNEGEVAAFIRGDSISSDSLPQAVEEADLRTILDQLFGEATDE
PDWQKIAAAVAATRRIAVISGGPGTGKTTTVAKLLAALVQLDEGRRLRIQLAAPTGKAAARLTESLGSAGKQLALTPEQR
ALFPTEASTLHRLLGAQPNSQRMRYHSGNRLHLDVLVVDEASMVDLPMMARLIAALPTQARVIFLGDRDQLASVEAGAVL
GDICRFAEQGYSVARAEQLSRLTGCRLQGQTAQAEAAVRDSLCLLRKSYRFDANSGIGQLAFAVNAGDGKRAMAALSGSF
ADVSGYPLAETQDYQALLDACVAGYRDYLRLVGEGADAVAVLAAFGHFQVLCALREGPFGIAGLNDRIETGLQRAGLIQR
KPGAAGRWYSGRPVMIGRNDSALGLFNGDIGIALRDESGELRVHFQLPDGSIKSVQPSRLPAHETAYAMTVHKSQGSEFD
HTVLVLPNHFLPVLTRELVYTAITRARRQLSLYAIDAVLMRAIRTPTQRRSGLAERLQLKA

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=601, Percent_Identity=61.2312811980033, Blast_Score=653, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66621; Mature: 66621

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLEQAQALGVLRPLDLQFASVVAGADEPEILLAAACLSAEAGAGHVCLMLEQLLPEN
CCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHH
LFDGRQPELAQAVWLAAGQLDVAGWQRRLSASAAVSDGSTATPMVLQPQRLYLQRMWQNE
HCCCCCCHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHCCC
GEVAAFIRGDSISSDSLPQAVEEADLRTILDQLFGEATDEPDWQKIAAAVAATRRIAVIS
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEEE
GGPGTGKTTTVAKLLAALVQLDEGRRLRIQLAAPTGKAAARLTESLGSAGKQLALTPEQR
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCHHC
ALFPTEASTLHRLLGAQPNSQRMRYHSGNRLHLDVLVVDEASMVDLPMMARLIAALPTQA
CCCCCCHHHHHHHHCCCCCCCCCEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCE
RVIFLGDRDQLASVEAGAVLGDICRFAEQGYSVARAEQLSRLTGCRLQGQTAQAEAAVRD
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCHHHHHHHHH
SLCLLRKSYRFDANSGIGQLAFAVNAGDGKRAMAALSGSFADVSGYPLAETQDYQALLDA
HHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
CVAGYRDYLRLVGEGADAVAVLAAFGHFQVLCALREGPFGIAGLNDRIETGLQRAGLIQR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCC
KPGAAGRWYSGRPVMIGRNDSALGLFNGDIGIALRDESGELRVHFQLPDGSIKSVQPSRL
CCCCCCCCCCCCEEEEECCCCEEEEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCCCC
PAHETAYAMTVHKSQGSEFDHTVLVLPNHFLPVLTRELVYTAITRARRQLSLYAIDAVLM
CCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIRTPTQRRSGLAERLQLKA
HHHCCCHHHHHCHHHHHHCCC
>Mature Secondary Structure
MIALLEQAQALGVLRPLDLQFASVVAGADEPEILLAAACLSAEAGAGHVCLMLEQLLPEN
CCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHH
LFDGRQPELAQAVWLAAGQLDVAGWQRRLSASAAVSDGSTATPMVLQPQRLYLQRMWQNE
HCCCCCCHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHCCC
GEVAAFIRGDSISSDSLPQAVEEADLRTILDQLFGEATDEPDWQKIAAAVAATRRIAVIS
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCEEEEEE
GGPGTGKTTTVAKLLAALVQLDEGRRLRIQLAAPTGKAAARLTESLGSAGKQLALTPEQR
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCHHC
ALFPTEASTLHRLLGAQPNSQRMRYHSGNRLHLDVLVVDEASMVDLPMMARLIAALPTQA
CCCCCCHHHHHHHHCCCCCCCCCEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCE
RVIFLGDRDQLASVEAGAVLGDICRFAEQGYSVARAEQLSRLTGCRLQGQTAQAEAAVRD
EEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEECCCCHHHHHHHHH
SLCLLRKSYRFDANSGIGQLAFAVNAGDGKRAMAALSGSFADVSGYPLAETQDYQALLDA
HHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
CVAGYRDYLRLVGEGADAVAVLAAFGHFQVLCALREGPFGIAGLNDRIETGLQRAGLIQR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCC
KPGAAGRWYSGRPVMIGRNDSALGLFNGDIGIALRDESGELRVHFQLPDGSIKSVQPSRL
CCCCCCCCCCCCEEEEECCCCEEEEEECCEEEEEECCCCCEEEEEECCCCCCCCCCCCCC
PAHETAYAMTVHKSQGSEFDHTVLVLPNHFLPVLTRELVYTAITRARRQLSLYAIDAVLM
CCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAIRTPTQRRSGLAERLQLKA
HHHCCCHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]