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The map label for this gene is cmpR [H]

Identifier: 157371972

GI number: 157371972

Start: 4126531

End: 4127409

Strand: Reverse

Name: cmpR [H]

Synonym: Spro_3737

Alternate gene names: 157371972

Gene position: 4127409-4126531 (Counterclockwise)

Preceding gene: 157371980

Following gene: 157371965

Centisome position: 75.75

GC content: 59.5

Gene sequence:

>879_bases
ATGAACCTGAAACAGATACGCTTTGCGTTGGCGGTAGCCGAAGAGCAGAGCTTTACCCGGGCGGCGCAGCGCTGCCATAC
GGTGCAGTCTGCCCTTAGCCACCAGATCGCCAAACTGGAAGAGGAGCTGGGCTGTACATTGTTCGAACGCACCTCGCGGC
GGGTCAGGCTGACCACCGCCGGGCAGGCGTTTATTCAACCGGCGCAACGGCTGCTGGCGGCGAAACAGGCGCTGGTGGAA
GAGGTGGTTGCCGCCAGCGGCACGGTATCCGGCACCCTGACCATCGGCACTATTTCAACCATAAACGCGATTGATCTGAC
CGAAAAACTGGGCAACTTTCATCGCCATTATCCGGCGGTGAATATCCGGCTGTACGTGGGCATGAGCGAAGCATTGCTGG
AAGACGTCCGCCAACAAAAGACGGACGTGGCGTTTGTCGGTCTCTGGCCGGGGGATATTGATATGCTGCCGGTGTCGCAT
CGGCAGCTAACCGATGAGCCGCTGGTCGCGCTGGTGGCGACGCAGCATCCGCTGGCCAGTCGTCAACGGGTCAATCTGCA
AACCCTGTCAGAAGTGCCGCTGGTGGACTTTTACAGCGGGACCGGTGCCCGGCGGCAGACCGACCGTGCGTTTCAGGCGG
CAGGTATCAAGCGGCATGTCAGTTTTGAAATTGACCATATCGAATGGCTGGAAAATCTGGTGCGGCGTGGGTTGGCGGCA
GGCATTGTGCCCATCTCGACGGCGCAGCGTTTGAGTTCGCTGGTGTCGATCCCGATCGAGGATGGTCCGCGGCGACAGGT
ATACTGCGTATGGCCGCAGCCACTGTCCAGAACCGCCGAGCGGTTTTTGCAGTTTAGTGGGATAGCTATTGCTGAATGA

Upstream 100 bases:

>100_bases
TATTAATCACAGGGAAAAGTTAGCCGAAGTATCGGGCACGACAGCCGGCGAATCCAATGTATAATTTTCATTTGATCAAT
CTCATTTTGCGATAGATGCC

Downstream 100 bases:

>100_bases
ATAGAACGGGGCGCAGTGGTGAACTGCGCCCCGGTGTTATTACTTCTTCGCGGCTTCGGCGGCGGTTTTCACCCAGCCGT
CAAAGGTGGCCTGATGCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MNLKQIRFALAVAEEQSFTRAAQRCHTVQSALSHQIAKLEEELGCTLFERTSRRVRLTTAGQAFIQPAQRLLAAKQALVE
EVVAASGTVSGTLTIGTISTINAIDLTEKLGNFHRHYPAVNIRLYVGMSEALLEDVRQQKTDVAFVGLWPGDIDMLPVSH
RQLTDEPLVALVATQHPLASRQRVNLQTLSEVPLVDFYSGTGARRQTDRAFQAAGIKRHVSFEIDHIEWLENLVRRGLAA
GIVPISTAQRLSSLVSIPIEDGPRRQVYCVWPQPLSRTAERFLQFSGIAIAE

Sequences:

>Translated_292_residues
MNLKQIRFALAVAEEQSFTRAAQRCHTVQSALSHQIAKLEEELGCTLFERTSRRVRLTTAGQAFIQPAQRLLAAKQALVE
EVVAASGTVSGTLTIGTISTINAIDLTEKLGNFHRHYPAVNIRLYVGMSEALLEDVRQQKTDVAFVGLWPGDIDMLPVSH
RQLTDEPLVALVATQHPLASRQRVNLQTLSEVPLVDFYSGTGARRQTDRAFQAAGIKRHVSFEIDHIEWLENLVRRGLAA
GIVPISTAQRLSSLVSIPIEDGPRRQVYCVWPQPLSRTAERFLQFSGIAIAE
>Mature_292_residues
MNLKQIRFALAVAEEQSFTRAAQRCHTVQSALSHQIAKLEEELGCTLFERTSRRVRLTTAGQAFIQPAQRLLAAKQALVE
EVVAASGTVSGTLTIGTISTINAIDLTEKLGNFHRHYPAVNIRLYVGMSEALLEDVRQQKTDVAFVGLWPGDIDMLPVSH
RQLTDEPLVALVATQHPLASRQRVNLQTLSEVPLVDFYSGTGARRQTDRAFQAAGIKRHVSFEIDHIEWLENLVRRGLAA
GIVPISTAQRLSSLVSIPIEDGPRRQVYCVWPQPLSRTAERFLQFSGIAIAE

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=30.3448275862069, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI157672245, Length=259, Percent_Identity=31.6602316602317, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=29.8969072164948, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=30.8943089430894, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693105, Length=286, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787530, Length=249, Percent_Identity=26.9076305220884, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787806, Length=255, Percent_Identity=28.2352941176471, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788887, Length=215, Percent_Identity=32.093023255814, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788296, Length=255, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=154, Percent_Identity=30.5194805194805, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=152, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=247, Percent_Identity=27.9352226720648, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367136, Length=259, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=210, Percent_Identity=30.952380952381, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788481, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081904, Length=217, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787949, Length=173, Percent_Identity=27.7456647398844, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=260, Percent_Identity=27.3076923076923, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=165, Percent_Identity=29.6969696969697, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787128, Length=144, Percent_Identity=32.6388888888889, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787589, Length=149, Percent_Identity=30.8724832214765, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786401, Length=136, Percent_Identity=30.1470588235294, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32369; Mature: 32369

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQIRFALAVAEEQSFTRAAQRCHTVQSALSHQIAKLEEELGCTLFERTSRRVRLTTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEC
GQAFIQPAQRLLAAKQALVEEVVAASGTVSGTLTIGTISTINAIDLTEKLGNFHRHYPAV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCEE
NIRLYVGMSEALLEDVRQQKTDVAFVGLWPGDIDMLPVSHRQLTDEPLVALVATQHPLAS
EEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCEEECCCHHHCCCCHHEEEEECCCCCCC
RQRVNLQTLSEVPLVDFYSGTGARRQTDRAFQAAGIKRHVSFEIDHIEWLENLVRRGLAA
CCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHC
GIVPISTAQRLSSLVSIPIEDGPRRQVYCVWPQPLSRTAERFLQFSGIAIAE
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MNLKQIRFALAVAEEQSFTRAAQRCHTVQSALSHQIAKLEEELGCTLFERTSRRVRLTTA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEC
GQAFIQPAQRLLAAKQALVEEVVAASGTVSGTLTIGTISTINAIDLTEKLGNFHRHYPAV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCEE
NIRLYVGMSEALLEDVRQQKTDVAFVGLWPGDIDMLPVSHRQLTDEPLVALVATQHPLAS
EEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCEEECCCHHHCCCCHHEEEEECCCCCCC
RQRVNLQTLSEVPLVDFYSGTGARRQTDRAFQAAGIKRHVSFEIDHIEWLENLVRRGLAA
CCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHC
GIVPISTAQRLSSLVSIPIEDGPRRQVYCVWPQPLSRTAERFLQFSGIAIAE
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]