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The map label for this gene is yajO [H]

Identifier: 157371786

GI number: 157371786

Start: 3923078

End: 3924031

Strand: Reverse

Name: yajO [H]

Synonym: Spro_3551

Alternate gene names: 157371786

Gene position: 3924031-3923078 (Counterclockwise)

Preceding gene: 157371793

Following gene: 157371782

Centisome position: 72.02

GC content: 57.34

Gene sequence:

>954_bases
ATGAGCAACAGAGAACTGGGCCGTTCGGGCATTAAAGTACCGGCATTGACCTTCGGCGGTAACGTGTTTGGTTGGACTGC
CGATCGCGAAACCTCTTTCAGCCTGCTGGATGCGCTGGTGGAGAACCAGCTCAATTTCATCGATACCGCCGACGTGTATT
CCAGTTGGGCGCCGGGCAATCAGGGCGGAGAGTCGGAGACCACCATTGGACAATGGCTGAAAAAAACCGGTAAGCGCGAC
CAGGTCATCATTGCCACCAAAGTGGGCAAGCCGATGGGCGAAGGCAAACAGGGGCTGTCGCCGCGCTATATCCAGCAGGC
GGTTGAGGATTCACTGCGCCGTTTGCAGACCGATTATATCGACCTTTATCAATCGCATGATGACGACCGGGACACGCCAC
TGGCAGAAACTCTGGCGGCGTTTGATGCGCTGATCAAGGCCGGCAAGGTGCGAGCGATAGGCGCTTCCAACTATCAGGCC
GATCGTCTGGAAGAAGCACTGAACGTCAGCGAGCGGGAAGGGTTGGCGCGTTACGAAACCCTGCAGCCGGAATACAACCT
GTATGCGCGAGAAGGCTATGAGCAGGGGCTGGAGGCGGTGGCGCAGCGCCATGGACTGGGCGTGATTAACTTCTTCTCGC
TGGCCAGTGGTTTCCTGACCGGCAAATATCGCAGCGAGCAAGATATCGGCAAGAGCCAGCGTGGCGACAGAGTGATTGGG
CAATATCTTAATCCGCGCGGTTTAAAAATTCTGACGGCGTTGGATAGCGTTGCGGCGAAGCACCAGACTTCACCCGCGCA
GGTTTCATTGGCCTGGCTGATAGCGCGGCCGAGCATTACAGCACCGATCGTCAGCGCAACCTCGTTAACGCAGTTGGATG
AGTTGGTTAGCGCTACCCGTCTGCGGTTGGATGCCGAGGATATCAGCACCCTGAACCAGGCCAGCGCCTGGTAA

Upstream 100 bases:

>100_bases
TAAGAGACTTAATCCGGCTTATAGCCAATACGTTTTGGCCTATTTCTCGGTTTGGCGCTAATAATTACCCTGCGAATCAT
TAATTCCCTTGGAGCATACA

Downstream 100 bases:

>100_bases
TCGGGTTAGCTGCGCACGGTGTTAATCAATGACAGCAACTGCGTCAGGCAGGCTTCAACGGTGCGCCCAGCGGTATCAAT
CGTCACCACCGGTGTGCTCC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSNRELGRSGIKVPALTFGGNVFGWTADRETSFSLLDALVENQLNFIDTADVYSSWAPGNQGGESETTIGQWLKKTGKRD
QVIIATKVGKPMGEGKQGLSPRYIQQAVEDSLRRLQTDYIDLYQSHDDDRDTPLAETLAAFDALIKAGKVRAIGASNYQA
DRLEEALNVSEREGLARYETLQPEYNLYAREGYEQGLEAVAQRHGLGVINFFSLASGFLTGKYRSEQDIGKSQRGDRVIG
QYLNPRGLKILTALDSVAAKHQTSPAQVSLAWLIARPSITAPIVSATSLTQLDELVSATRLRLDAEDISTLNQASAW

Sequences:

>Translated_317_residues
MSNRELGRSGIKVPALTFGGNVFGWTADRETSFSLLDALVENQLNFIDTADVYSSWAPGNQGGESETTIGQWLKKTGKRD
QVIIATKVGKPMGEGKQGLSPRYIQQAVEDSLRRLQTDYIDLYQSHDDDRDTPLAETLAAFDALIKAGKVRAIGASNYQA
DRLEEALNVSEREGLARYETLQPEYNLYAREGYEQGLEAVAQRHGLGVINFFSLASGFLTGKYRSEQDIGKSQRGDRVIG
QYLNPRGLKILTALDSVAAKHQTSPAQVSLAWLIARPSITAPIVSATSLTQLDELVSATRLRLDAEDISTLNQASAW
>Mature_316_residues
SNRELGRSGIKVPALTFGGNVFGWTADRETSFSLLDALVENQLNFIDTADVYSSWAPGNQGGESETTIGQWLKKTGKRDQ
VIIATKVGKPMGEGKQGLSPRYIQQAVEDSLRRLQTDYIDLYQSHDDDRDTPLAETLAAFDALIKAGKVRAIGASNYQAD
RLEEALNVSEREGLARYETLQPEYNLYAREGYEQGLEAVAQRHGLGVINFFSLASGFLTGKYRSEQDIGKSQRGDRVIGQ
YLNPRGLKILTALDSVAAKHQTSPAQVSLAWLIARPSITAPIVSATSLTQLDELVSATRLRLDAEDISTLNQASAW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436966, Length=314, Percent_Identity=28.9808917197452, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=28.9808917197452, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436962, Length=314, Percent_Identity=28.9808917197452, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4504825, Length=311, Percent_Identity=28.9389067524116, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=28.343949044586, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI27436971, Length=311, Percent_Identity=28.9389067524116, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI223718702, Length=332, Percent_Identity=29.8192771084337, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI41152114, Length=332, Percent_Identity=30.421686746988, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI41327764, Length=289, Percent_Identity=30.7958477508651, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223718708, Length=173, Percent_Identity=33.5260115606936, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=34.1692789968652, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1789199, Length=332, Percent_Identity=31.6265060240964, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=30.8868501529052, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788081, Length=316, Percent_Identity=28.4810126582279, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786400, Length=300, Percent_Identity=28, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17550248, Length=320, Percent_Identity=24.375, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=29.4642857142857, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=28.2282282282282, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=27.8523489932886, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=301, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321052, Length=168, Percent_Identity=34.5238095238095, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=244, Percent_Identity=26.6393442622951, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24640980, Length=324, Percent_Identity=24.6913580246914, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45549126, Length=324, Percent_Identity=24.6913580246914, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646155, Length=176, Percent_Identity=33.5227272727273, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646159, Length=232, Percent_Identity=29.7413793103448, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644950, Length=329, Percent_Identity=25.2279635258359, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34770; Mature: 34639

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRELGRSGIKVPALTFGGNVFGWTADRETSFSLLDALVENQLNFIDTADVYSSWAPGN
CCCCHHCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
QGGESETTIGQWLKKTGKRDQVIIATKVGKPMGEGKQGLSPRYIQQAVEDSLRRLQTDYI
CCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLYQSHDDDRDTPLAETLAAFDALIKAGKVRAIGASNYQADRLEEALNVSEREGLARYET
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCHHHHCHHHHHH
LQPEYNLYAREGYEQGLEAVAQRHGLGVINFFSLASGFLTGKYRSEQDIGKSQRGDRVIG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHH
QYLNPRGLKILTALDSVAAKHQTSPAQVSLAWLIARPSITAPIVSATSLTQLDELVSATR
HHCCCCCHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LRLDAEDISTLNQASAW
HHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SNRELGRSGIKVPALTFGGNVFGWTADRETSFSLLDALVENQLNFIDTADVYSSWAPGN
CCCHHCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
QGGESETTIGQWLKKTGKRDQVIIATKVGKPMGEGKQGLSPRYIQQAVEDSLRRLQTDYI
CCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLYQSHDDDRDTPLAETLAAFDALIKAGKVRAIGASNYQADRLEEALNVSEREGLARYET
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCHHHHCHHHHHH
LQPEYNLYAREGYEQGLEAVAQRHGLGVINFFSLASGFLTGKYRSEQDIGKSQRGDRVIG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHH
QYLNPRGLKILTALDSVAAKHQTSPAQVSLAWLIARPSITAPIVSATSLTQLDELVSATR
HHCCCCCHHHHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
LRLDAEDISTLNQASAW
HHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]