| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is entA [H]
Identifier: 157371655
GI number: 157371655
Start: 3782523
End: 3783281
Strand: Reverse
Name: entA [H]
Synonym: Spro_3418
Alternate gene names: 157371655
Gene position: 3783281-3782523 (Counterclockwise)
Preceding gene: 157371656
Following gene: 157371654
Centisome position: 69.43
GC content: 58.63
Gene sequence:
>759_bases ATGGAACAACGGGGCGATTTCGCCGGTAAGCGAGTCTGGGTCACTGGTGCTGGGGCCGGGATTGGTCTGGCAACGGCATT GGCGTTTGTGCAGGCCGGTGCCGAAGTGATTGGCTTTGATAAACATTTTGGCGAGCCGGAATACGCATTCCGCACCGAAG TGCTGGATATTGCCGACAGTGATGCGGTAGATCGGGTTTGCGGACGTTTGCTGGCGGAGCAGGGGGCGTTGGACGTGCTG GTCAACGGTGCCGGAATTTTGCGTATGGGGCTGGCGGATGAAACCAGCACCGCAGATTGGCTGGCTTGCCTGGCCGTCAA TGCCGGTGGGGCATTTAATATGTTCCGCCACGCTTTGCCGGTATTCCGTCGCCAACGACGCGGTGCGATTGTCAGCGTGG CATCTAACGCCGCGCATGTGCCGCGCGTCGGTATGGCGGCCTATTGTGCTTCCAAGGCGGCATTACGCAGCCTGTGCAAC ACCGTAGGGCTGGAGATGGCCCCTTATGGCGTACGTTGCAACCTGGTTTCGCCAGGATCGACCAATACGCCAATGCAGCG CGGCATGTGGCAGGATGAAACCGGTGAGCAGAACACCATTAACGGTTTCCCGGAACAGTTCAAATTGGGCATTCCGCTGG GTAAAATTGCTCAGCCGCAGGAAATCGCCGATGCCATTTTGTTTCTGGCTTCCGATCGCGCCAGCCATATCACCATGCAG GATATTGTGATTGACGGCGGGGCGACGCTGGCGGCCTGA
Upstream 100 bases:
>100_bases CACGTTGGCGTAAAATTCGTGGCGATATTGATTTTATCGCACTGGCCAAGAACCCGACCATCGATGGCTGGTGGACGCTG CTGTCGGAGGGAAAAGCCTG
Downstream 100 bases:
>100_bases TAATCAGGTTCTATCTTCGCAATAGCCACAAGGCGCTGCAAGCAGCGCCTTTATTTTGTAGTGAAATAGTTGTCTTTAAT CCCGAGATACTCGGGCCTAG
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 252; Mature: 252
Protein sequence:
>252_residues MEQRGDFAGKRVWVTGAGAGIGLATALAFVQAGAEVIGFDKHFGEPEYAFRTEVLDIADSDAVDRVCGRLLAEQGALDVL VNGAGILRMGLADETSTADWLACLAVNAGGAFNMFRHALPVFRRQRRGAIVSVASNAAHVPRVGMAAYCASKAALRSLCN TVGLEMAPYGVRCNLVSPGSTNTPMQRGMWQDETGEQNTINGFPEQFKLGIPLGKIAQPQEIADAILFLASDRASHITMQ DIVIDGGATLAA
Sequences:
>Translated_252_residues MEQRGDFAGKRVWVTGAGAGIGLATALAFVQAGAEVIGFDKHFGEPEYAFRTEVLDIADSDAVDRVCGRLLAEQGALDVL VNGAGILRMGLADETSTADWLACLAVNAGGAFNMFRHALPVFRRQRRGAIVSVASNAAHVPRVGMAAYCASKAALRSLCN TVGLEMAPYGVRCNLVSPGSTNTPMQRGMWQDETGEQNTINGFPEQFKLGIPLGKIAQPQEIADAILFLASDRASHITMQ DIVIDGGATLAA >Mature_252_residues MEQRGDFAGKRVWVTGAGAGIGLATALAFVQAGAEVIGFDKHFGEPEYAFRTEVLDIADSDAVDRVCGRLLAEQGALDVL VNGAGILRMGLADETSTADWLACLAVNAGGAFNMFRHALPVFRRQRRGAIVSVASNAAHVPRVGMAAYCASKAALRSLCN TVGLEMAPYGVRCNLVSPGSTNTPMQRGMWQDETGEQNTINGFPEQFKLGIPLGKIAQPQEIADAILFLASDRASHITMQ DIVIDGGATLAA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=31.7460317460317, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=27.5193798449612, Blast_Score=101, Evalue=7e-22, Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=28.8461538461538, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=29.5652173913043, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=29.3436293436293, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI40254992, Length=195, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI4504505, Length=202, Percent_Identity=33.1683168316832, Blast_Score=84, Evalue=8e-17, Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=24.904214559387, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI119392083, Length=217, Percent_Identity=28.110599078341, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=29.7435897435897, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI22507405, Length=240, Percent_Identity=25.8333333333333, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4503817, Length=234, Percent_Identity=26.0683760683761, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7706318, Length=183, Percent_Identity=28.4153005464481, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=24.5059288537549, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=66.3967611336032, Blast_Score=335, Evalue=2e-93, Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=30.5555555555556, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=31.2741312741313, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=27.6, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=24.7058823529412, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=25.8064516129032, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=29.0836653386454, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=32.0158102766798, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=32.2834645669291, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1789378, Length=270, Percent_Identity=27.037037037037, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=28.1746031746032, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=30.1675977653631, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1786701, Length=227, Percent_Identity=25.1101321585903, Blast_Score=65, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=32.7935222672065, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=30.5882352941176, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=31.0483870967742, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=32.8301886792453, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=30.6818181818182, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=32.1969696969697, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=31.9548872180451, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=31.9548872180451, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=31.0606060606061, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=31.3207547169811, Blast_Score=94, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=29.6442687747036, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=30.3703703703704, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=28.5171102661597, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=32.3308270676692, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=29.811320754717, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=29.1512915129151, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=27.6679841897233, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=32.5842696629214, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=30.2238805970149, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=31.3829787234043, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=25.8823529411765, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=29.368029739777, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=27.5590551181102, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17564282, Length=199, Percent_Identity=29.1457286432161, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=28.0769230769231, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=28.6764705882353, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17551412, Length=275, Percent_Identity=27.6363636363636, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193203115, Length=254, Percent_Identity=24.8031496062992, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17508651, Length=200, Percent_Identity=25.5, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17557780, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=26.0204081632653, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI193203117, Length=250, Percent_Identity=24.4, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=26.6917293233083, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17507613, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI32563809, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538182, Length=190, Percent_Identity=27.8947368421053, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=5e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=260, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=35.0393700787402, Blast_Score=110, Evalue=8e-25, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=33.7349397590361, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=31.0077519379845, Blast_Score=103, Evalue=8e-23, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=33.596837944664, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=31.7460317460317, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=31.3492063492063, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI21356301, Length=237, Percent_Identity=31.6455696202532, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=32.9411764705882, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=28.3464566929134, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI18859837, Length=202, Percent_Identity=31.6831683168317, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=27.9187817258883, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281364892, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 26595; Mature: 26595
Theoretical pI: Translated: 5.31; Mature: 5.31
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 5.2 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 5.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEQRGDFAGKRVWVTGAGAGIGLATALAFVQAGAEVIGFDKHFGEPEYAFRTEVLDIADS CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHEEECHHHCCCCCHHHHHHHHHCCCC DAVDRVCGRLLAEQGALDVLVNGAGILRMGLADETSTADWLACLAVNAGGAFNMFRHALP HHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCHHHHEEHEEECCCCHHHHHHHHHH VFRRQRRGAIVSVASNAAHVPRVGMAAYCASKAALRSLCNTVGLEMAPYGVRCNLVSPGS HHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC TNTPMQRGMWQDETGEQNTINGFPEQFKLGIPLGKIAQPQEIADAILFLASDRASHITMQ CCCCHHHCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE DIVIDGGATLAA HEEEECCCCCCC >Mature Secondary Structure MEQRGDFAGKRVWVTGAGAGIGLATALAFVQAGAEVIGFDKHFGEPEYAFRTEVLDIADS CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHEEECHHHCCCCCHHHHHHHHHCCCC DAVDRVCGRLLAEQGALDVLVNGAGILRMGLADETSTADWLACLAVNAGGAFNMFRHALP HHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCHHHHEEHEEECCCCHHHHHHHHHH VFRRQRRGAIVSVASNAAHVPRVGMAAYCASKAALRSLCNTVGLEMAPYGVRCNLVSPGS HHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC TNTPMQRGMWQDETGEQNTINGFPEQFKLGIPLGKIAQPQEIADAILFLASDRASHITMQ CCCCHHHCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE DIVIDGGATLAA HEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]