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The map label for this gene is catB4 [H]

Identifier: 157371582

GI number: 157371582

Start: 3701295

End: 3701924

Strand: Reverse

Name: catB4 [H]

Synonym: Spro_3345

Alternate gene names: 157371582

Gene position: 3701924-3701295 (Counterclockwise)

Preceding gene: 157371583

Following gene: 157371578

Centisome position: 67.94

GC content: 55.24

Gene sequence:

>630_bases
ATGACTGAAAAACACTGGTCAAAAACAGAACTGCTGCACCAAACGGTGACCAACCCCAATATTATCGTCAAAGGGACCCA
CAGCTATTACAGCGACTACCTGGATGACGGTTTTGAGCGCTCCGTGGTGCGTTATTTGCACGGGGACGAGGTCAGCCAAC
AGTGGCAGCCGCTAGGGGCGATAGACCAATTGCTGATCGGCGATTATGTCTGCATTGCCGCCGAGGCCGTGATCCTGATG
GGGGGTAATCATACTCACCGTGCCGATTGGTTCTGCCTGTATCCGATGATGGAAAGCATTCTGGCTTCCTATCAGCCGAG
GGGCGACACCCGGTTAGGGGACGGCTGTTGGATTGGGATGCGGGCGATGCTGATGCCGGGTGTGAGCATTGGGGAAGGGG
CGATAGTGGCTGCAGGCAGTATTGTGACCAAGGATGTTGAACCTTACGCTATCGTGGGCGGCAATCCGGCACGGCCAATC
AAGCTGCGGTTTAGCCCGCAGACCATCGCCCGGTTATTGGCTTTGCGTATTTATGATTTGTCGGCGGAAGATTTTGCCCG
CGTGCAGCCCTTGCTGGCCGATGATGATATTGCGGCCCTGGAACGGGCGATAGCTGAAATTAAGCGTTAA

Upstream 100 bases:

>100_bases
AAACGGGCGTTAATCGCTTAGTCCGGCAGTGTTTTGCGACCAAAAAACACTGCCACAGACTTTAGGCTGTGGCTCTTGCA
ATGAATATAGAGAAAGCGCC

Downstream 100 bases:

>100_bases
GTGAAAAGGGCGGGAATAACCCCGCCCTTTGACTTATTCGGCCTTGGCCGCTTCCACCGTTTGGCGACGTTTGCGCACTA
TGCGCAACACCAGCGGCAGC

Product: hexapaptide repeat-containing transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTEKHWSKTELLHQTVTNPNIIVKGTHSYYSDYLDDGFERSVVRYLHGDEVSQQWQPLGAIDQLLIGDYVCIAAEAVILM
GGNHTHRADWFCLYPMMESILASYQPRGDTRLGDGCWIGMRAMLMPGVSIGEGAIVAAGSIVTKDVEPYAIVGGNPARPI
KLRFSPQTIARLLALRIYDLSAEDFARVQPLLADDDIAALERAIAEIKR

Sequences:

>Translated_209_residues
MTEKHWSKTELLHQTVTNPNIIVKGTHSYYSDYLDDGFERSVVRYLHGDEVSQQWQPLGAIDQLLIGDYVCIAAEAVILM
GGNHTHRADWFCLYPMMESILASYQPRGDTRLGDGCWIGMRAMLMPGVSIGEGAIVAAGSIVTKDVEPYAIVGGNPARPI
KLRFSPQTIARLLALRIYDLSAEDFARVQPLLADDDIAALERAIAEIKR
>Mature_208_residues
TEKHWSKTELLHQTVTNPNIIVKGTHSYYSDYLDDGFERSVVRYLHGDEVSQQWQPLGAIDQLLIGDYVCIAAEAVILMG
GNHTHRADWFCLYPMMESILASYQPRGDTRLGDGCWIGMRAMLMPGVSIGEGAIVAAGSIVTKDVEPYAIVGGNPARPIK
LRFSPQTIARLLALRIYDLSAEDFARVQPLLADDDIAALERAIAEIKR

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=50, Percent_Identity=56, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 23189; Mature: 23058

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKHWSKTELLHQTVTNPNIIVKGTHSYYSDYLDDGFERSVVRYLHGDEVSQQWQPLGA
CCCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCHHH
IDQLLIGDYVCIAAEAVILMGGNHTHRADWFCLYPMMESILASYQPRGDTRLGDGCWIGM
HHHHHHHHHHHHHHCEEEEECCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCHHHHH
RAMLMPGVSIGEGAIVAAGSIVTKDVEPYAIVGGNPARPIKLRFSPQTIARLLALRIYDL
HHHHCCCCCCCCCCEEECCCEEECCCCCEEEECCCCCCEEEEEECHHHHHHHHHHHHHCC
SAEDFARVQPLLADDDIAALERAIAEIKR
CHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEKHWSKTELLHQTVTNPNIIVKGTHSYYSDYLDDGFERSVVRYLHGDEVSQQWQPLGA
CCCCHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCHHH
IDQLLIGDYVCIAAEAVILMGGNHTHRADWFCLYPMMESILASYQPRGDTRLGDGCWIGM
HHHHHHHHHHHHHHCEEEEECCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCHHHHH
RAMLMPGVSIGEGAIVAAGSIVTKDVEPYAIVGGNPARPIKLRFSPQTIARLLALRIYDL
HHHHCCCCCCCCCCEEECCCEEECCCCCEEEECCCCCCEEEEEECHHHHHHHHHHHHHCC
SAEDFARVQPLLADDDIAALERAIAEIKR
CHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7793874 [H]