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The map label for this gene is nuoA

Identifier: 157371545

GI number: 157371545

Start: 3663064

End: 3663504

Strand: Reverse

Name: nuoA

Synonym: Spro_3308

Alternate gene names: 157371545

Gene position: 3663504-3663064 (Counterclockwise)

Preceding gene: 157371546

Following gene: 157371544

Centisome position: 67.23

GC content: 54.88

Gene sequence:

>441_bases
ATGTCAACAACCACTGAAGTTATCGCTCATCACTGGGCGTTCGCCGTATTTTTTGTCGTGGCAATCGGGCTTTGCTGTTT
AATGCTGATGGGCGCGTTCTTCCTGGGTGGGAGAGCCCGTGCGCGCGCCAAACATACCCCGTTTGAATCAGGCATCGACT
CGGTCGGCACGGCGCGCATGCGTCTGTCCGCCAAGTTCTACCTGGTCGCCATGTTCTTCGTTATTTTCGATGTTGAAGCC
TTGTACCTTTACGCCTGGTCGGTCTCCATACGTGAGAGCGGTTGGGTAGGCTTCATCGAAGCCGCCATTTTCATTTTGGT
GTTATTGGCTGGGCTGGTTTATCTGGTGCGTATTGGCGCATTGGATTGGACTCCGGTGCGCTCCAGGCGCCAGAGCAAGC
CAGGCACAATCAAAAACGCCACCAACAGTCACCCGCAGTAG

Upstream 100 bases:

>100_bases
GTGTGGTTTATTTATCCTTCCCTTAAATCGATGTGGTGCACTAACTGCCAGAAACAAGAGCAGAGCGATCGACGCCACTT
TTGATGAGTAAGCATAGAGT

Downstream 100 bases:

>100_bases
TCGGTTAAAAACGAGGCATTAAGATGGACTATACGCTCACCCGCATAGACCCGAACGGTGAGAACGACCGTTACCCCCTG
CAAAAACAGGAGGTCGTCGC

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MSTTTEVIAHHWAFAVFFVVAIGLCCLMLMGAFFLGGRARARAKHTPFESGIDSVGTARMRLSAKFYLVAMFFVIFDVEA
LYLYAWSVSIRESGWVGFIEAAIFILVLLAGLVYLVRIGALDWTPVRSRRQSKPGTIKNATNSHPQ

Sequences:

>Translated_146_residues
MSTTTEVIAHHWAFAVFFVVAIGLCCLMLMGAFFLGGRARARAKHTPFESGIDSVGTARMRLSAKFYLVAMFFVIFDVEA
LYLYAWSVSIRESGWVGFIEAAIFILVLLAGLVYLVRIGALDWTPVRSRRQSKPGTIKNATNSHPQ
>Mature_145_residues
STTTEVIAHHWAFAVFFVVAIGLCCLMLMGAFFLGGRARARAKHTPFESGIDSVGTARMRLSAKFYLVAMFFVIFDVEAL
YLYAWSVSIRESGWVGFIEAAIFILVLLAGLVYLVRIGALDWTPVRSRRQSKPGTIKNATNSHPQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=144, Percent_Identity=79.1666666666667, Blast_Score=238, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_SERP5 (A8GH16)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479534.1
- STRING:   A8GH16
- GeneID:   5603333
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3308
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- ProtClustDB:   PRK06602
- BioCyc:   SPRO399741:SPRO_3308-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 16221; Mature: 16090

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0x10089c68)-; HASH(0x109509c0)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTTEVIAHHWAFAVFFVVAIGLCCLMLMGAFFLGGRARARAKHTPFESGIDSVGTARM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHCCHHHHHHHHH
RLSAKFYLVAMFFVIFDVEALYLYAWSVSIRESGWVGFIEAAIFILVLLAGLVYLVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWTPVRSRRQSKPGTIKNATNSHPQ
CCCCCCHHHHCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
STTTEVIAHHWAFAVFFVVAIGLCCLMLMGAFFLGGRARARAKHTPFESGIDSVGTARM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHCCHHHHHHHHH
RLSAKFYLVAMFFVIFDVEALYLYAWSVSIRESGWVGFIEAAIFILVLLAGLVYLVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWTPVRSRRQSKPGTIKNATNSHPQ
CCCCCCHHHHCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA