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The map label for this gene is gap1 [H]

Identifier: 157371358

GI number: 157371358

Start: 3433741

End: 3434751

Strand: Reverse

Name: gap1 [H]

Synonym: Spro_3119

Alternate gene names: 157371358

Gene position: 3434751-3433741 (Counterclockwise)

Preceding gene: 157371359

Following gene: 157371353

Centisome position: 63.04

GC content: 56.18

Gene sequence:

>1011_bases
ATGGTCAAAGTAGGCATTAATGGATTCGGCAGGATCGGCAGGAACGTGTTGCGCGCAGCGTTAGGTCGCAGCGACTTTCA
GGTTGTGGCAATCAATGATTTGACCGACAGCAAAACCCTGGCGCACCTGCTGAAATACGATTCGCTTTCAGGGACTCTGG
CAGCCAGCGTCGAAGCCGGTGAGAACCAGTTGCTGCTCGATGGTCGGCCGATTCATGTTTTCTCCGAAAGAGATCCGGCT
GCCATCCCATGGAGCAGCGTGGGTGTTGAGGTAGTGATTGAGGCGACGGGCTTCTTCACCGACAAAGCCAAGGCCGAAGT
GCACATCACCCAAGGCGGTGCCAAGCGAGTCATTATCTCGGCACCGGGCAAGGACGATGATATTACGCTGGTGCTGGGCG
TTAACCATCAGCAATACGATCCGGCCAAACATTTTGTGGTCAGCAACGGTAGCTGTACCACTAACGGTCTGGCCCCTGCC
GCCCAGGTATTGCATCAGGCATTTGGTATTGAATACGGTTTGATGAATACCACCCATGCCTACACCAATAGCCAGGCGCT
GCATGACCAACCGGAAAAAGACCTGCGCGGTGCCCGTGCCGCAGCGGAGTCGATTGTGCCTTATTCCAGCGGTGCCGCCA
AAGCGCTCGGCAAGGTGATCCCGGAGCTGGACGGTCGACTGACCGGTTACTCGCTGCGGGTGCCGGTACCGGTAGTGTCT
ATCGTGGACTTAACGGTCACGCTGAAACGTGAAGTGACGGCCGAAGAGATCAACGCGGCTTTCCGCCAGGCTGCCGAATC
CGGCCCTCTCAAGGATATTCTTGGCTACAGCGATGAGCCTTTGGTGTCCAGTGATTATAGAGGCGACCCGCGTTCGTCGG
TAATTGATGGGCTTTCCACGCTGGTGATTGGCGGTAATTTGGTCAAGATCCTCGCCTGGTACGACAACGAGTGGGGCTTC
TCTAACCGGCTGGTGGATCTGGCGGTTCTGATGGAAAAACGCGGTTTGTAA

Upstream 100 bases:

>100_bases
CATTCCCGCATGTTGGCCTAAATTGATCTACAAACGTCATTTACGACACTGACCTCTCCGGTTTAGATTGGTGACAGAGC
CAATAATGAAGGAGTAGATC

Downstream 100 bases:

>100_bases
AAGAGTAGGGGCGCTGCATGCTGCGCCCCTGTAGTGAACCCGGTCAAGTTACAGTTGCGCGATCTGCATTAAATCTTGTT
TGGCCCCTGGCGCGACCGCC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MVKVGINGFGRIGRNVLRAALGRSDFQVVAINDLTDSKTLAHLLKYDSLSGTLAASVEAGENQLLLDGRPIHVFSERDPA
AIPWSSVGVEVVIEATGFFTDKAKAEVHITQGGAKRVIISAPGKDDDITLVLGVNHQQYDPAKHFVVSNGSCTTNGLAPA
AQVLHQAFGIEYGLMNTTHAYTNSQALHDQPEKDLRGARAAAESIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
IVDLTVTLKREVTAEEINAAFRQAAESGPLKDILGYSDEPLVSSDYRGDPRSSVIDGLSTLVIGGNLVKILAWYDNEWGF
SNRLVDLAVLMEKRGL

Sequences:

>Translated_336_residues
MVKVGINGFGRIGRNVLRAALGRSDFQVVAINDLTDSKTLAHLLKYDSLSGTLAASVEAGENQLLLDGRPIHVFSERDPA
AIPWSSVGVEVVIEATGFFTDKAKAEVHITQGGAKRVIISAPGKDDDITLVLGVNHQQYDPAKHFVVSNGSCTTNGLAPA
AQVLHQAFGIEYGLMNTTHAYTNSQALHDQPEKDLRGARAAAESIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
IVDLTVTLKREVTAEEINAAFRQAAESGPLKDILGYSDEPLVSSDYRGDPRSSVIDGLSTLVIGGNLVKILAWYDNEWGF
SNRLVDLAVLMEKRGL
>Mature_336_residues
MVKVGINGFGRIGRNVLRAALGRSDFQVVAINDLTDSKTLAHLLKYDSLSGTLAASVEAGENQLLLDGRPIHVFSERDPA
AIPWSSVGVEVVIEATGFFTDKAKAEVHITQGGAKRVIISAPGKDDDITLVLGVNHQQYDPAKHFVVSNGSCTTNGLAPA
AQVLHQAFGIEYGLMNTTHAYTNSQALHDQPEKDLRGARAAAESIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
IVDLTVTLKREVTAEEINAAFRQAAESGPLKDILGYSDEPLVSSDYRGDPRSSVIDGLSTLVIGGNLVKILAWYDNEWGF
SNRLVDLAVLMEKRGL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=48.955223880597, Blast_Score=317, Evalue=7e-87,
Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=46.5465465465465, Blast_Score=293, Evalue=1e-79,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=50.1501501501502, Blast_Score=328, Evalue=2e-91,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=42.814371257485, Blast_Score=276, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=49.5575221238938, Blast_Score=314, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=49.2625368731563, Blast_Score=313, Evalue=7e-86,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=47.1299093655589, Blast_Score=293, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=47.1299093655589, Blast_Score=293, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=48.0243161094225, Blast_Score=313, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=48.0243161094225, Blast_Score=306, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=48.0243161094225, Blast_Score=304, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17933600, Length=336, Percent_Identity=50.297619047619, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI18110149, Length=336, Percent_Identity=50.297619047619, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI85725000, Length=336, Percent_Identity=50.297619047619, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI22023983, Length=336, Percent_Identity=50.297619047619, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=44.6107784431138, Blast_Score=282, Evalue=2e-76,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35927; Mature: 35927

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVGINGFGRIGRNVLRAALGRSDFQVVAINDLTDSKTLAHLLKYDSLSGTLAASVEAG
CEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECC
ENQLLLDGRPIHVFSERDPAAIPWSSVGVEVVIEATGFFTDKAKAEVHITQGGAKRVIIS
CCEEEECCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEE
APGKDDDITLVLGVNHQQYDPAKHFVVSNGSCTTNGLAPAAQVLHQAFGIEYGLMNTTHA
CCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEECCCCCCCC
YTNSQALHDQPEKDLRGARAAAESIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
CCCCCHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEE
IVDLTVTLKREVTAEEINAAFRQAAESGPLKDILGYSDEPLVSSDYRGDPRSSVIDGLST
EEEEEEEEEHHCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
LVIGGNLVKILAWYDNEWGFSNRLVDLAVLMEKRGL
EEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKVGINGFGRIGRNVLRAALGRSDFQVVAINDLTDSKTLAHLLKYDSLSGTLAASVEAG
CEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECC
ENQLLLDGRPIHVFSERDPAAIPWSSVGVEVVIEATGFFTDKAKAEVHITQGGAKRVIIS
CCEEEECCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEE
APGKDDDITLVLGVNHQQYDPAKHFVVSNGSCTTNGLAPAAQVLHQAFGIEYGLMNTTHA
CCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEECCCCCCCC
YTNSQALHDQPEKDLRGARAAAESIVPYSSGAAKALGKVIPELDGRLTGYSLRVPVPVVS
CCCCCHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEE
IVDLTVTLKREVTAEEINAAFRQAAESGPLKDILGYSDEPLVSSDYRGDPRSSVIDGLST
EEEEEEEEEHHCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
LVIGGNLVKILAWYDNEWGFSNRLVDLAVLMEKRGL
EEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA