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The map label for this gene is kbl [C]

Identifier: 157371268

GI number: 157371268

Start: 3331335

End: 3332558

Strand: Reverse

Name: kbl [C]

Synonym: Spro_3028

Alternate gene names: 157371268

Gene position: 3332558-3331335 (Counterclockwise)

Preceding gene: 157371269

Following gene: 157371267

Centisome position: 61.16

GC content: 55.47

Gene sequence:

>1224_bases
ATGACCAGCCGCAAGAAGATCATGCCAACCAACCAATATCGCAACAACGACAAAGCTATCGGTATTGGTAATCCCTTCTG
GGATATGTCAGAGCAGAACGGACTCGCAGGGATCGTCGCCGGACTCGAAAACGATCTCCTGTCCACCCTGAGTGGTCATC
AATTTGTCAATTTTAGCTGCTGTTCTTACCTGAATCTGGACTCCCATCCCAGGGTGATAGAAGGGGCTATCGACGCGGTA
CGTCGTTACGGCGTGCTGGATCACTGCATCGCCCGTAGCAGGGTCCAGCTTCCGGTGCTCAAAGAGCTGGAGGAATCGCT
CGGTGAACTGTTCCAGGCCGATGTTCTCAGTGGCGTGTCGGCCAGCAGCATCAGTGGGGGGCTGCTACCGCTGATCGCCT
CCGGACATTTGGGTAACGGTGTTCGGCCGTTAATGATCTTCGATAAACATGCTCATGTGTCTTTGGCGGCGGCAAAACCC
GCCTGTGCCGATGAAACCGAGGTCGTCACCTGCAATTACCACGATCTGGAGTTCATCAAGGACTGCTGCAAGAAATACCA
ACGGGTCTGCTACGTGGTTGACGGCAGCGATAGCCTGGGCGGCTATGCGCCGGTTAAAGAGTTGGCCGAACTGCAGGACA
AATACGGCCTGATGGTGTTCTACGATGATTCACATTCTATTTCCGCCTATGGCGAACGTGGGATCGGTTACGTTCGCTCA
CACAGCCCGGCGCTCAATGAGAACACCGTTATGGTGGTCACGCTCAACAAGGCTTTCGGCACCAGCGGGGCGGCGATACT
GCTCAACGGCTATTCACAGCCGATGTTGCGCCTGGTCGAGCGCTTTGGCGGCGGACTCAACTATTCGCAAAATCTGAACA
CTGCGGCCATCGGTGCCAGCCTGGCCTCTGCCGAAATTCACCGCACGGCAGAGCTGCCGATGCTGCAAAAGAAATTGTAC
GACAACATTGCGCTGTTCGATTCCCTGATCCCGACCGAGCAGAGCGGCAACGCCTACCCGATCCGACTGGTGCCGATGAG
CGATGAAACGGTGATCAGCGAAGGGCGTCAGGTGATTGAAGCCGGTTTCTATGTCTCACCGGTATTCTTCCCGATCGTCG
CCAAAGGCACTGCCGGTCTGCGGGTCATGATGCGTGCCGGACAAACAGAAGATCAAATTCGCCGTTTGTGCAAAATACTG
GCTGAAGTAAGGGCTCCCCAATGA

Upstream 100 bases:

>100_bases
GGCCTTATGTTTTGTATTCCGCGCTCTACACGGCTGCCTACCGTAAATTCAAAGGCATTTATAACTATCAACCCGAACCT
GCCAAGAAGGAAGGAATTTG

Downstream 100 bases:

>100_bases
CGGATAACACACGCGCCATTCCGCGCAGCATTCTGTATACGCCCGCCTTGTCGCTCAACCGGGTAGTCAAGGCGCTGACT
TATGACGCCGATGTCCACCT

Product: hypothetical protein

Products: NA

Alternate protein names: AONS/AKB ligase; 7-keto-8-amino-pelargonic acid synthase; 7-KAP synthase; KAPA synthase; 8-amino-7-ketopelargonate synthase; Alpha-oxoamine synthase; L-alanine--pimeloyl-CoA ligase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTSRKKIMPTNQYRNNDKAIGIGNPFWDMSEQNGLAGIVAGLENDLLSTLSGHQFVNFSCCSYLNLDSHPRVIEGAIDAV
RRYGVLDHCIARSRVQLPVLKELEESLGELFQADVLSGVSASSISGGLLPLIASGHLGNGVRPLMIFDKHAHVSLAAAKP
ACADETEVVTCNYHDLEFIKDCCKKYQRVCYVVDGSDSLGGYAPVKELAELQDKYGLMVFYDDSHSISAYGERGIGYVRS
HSPALNENTVMVVTLNKAFGTSGAAILLNGYSQPMLRLVERFGGGLNYSQNLNTAAIGASLASAEIHRTAELPMLQKKLY
DNIALFDSLIPTEQSGNAYPIRLVPMSDETVISEGRQVIEAGFYVSPVFFPIVAKGTAGLRVMMRAGQTEDQIRRLCKIL
AEVRAPQ

Sequences:

>Translated_407_residues
MTSRKKIMPTNQYRNNDKAIGIGNPFWDMSEQNGLAGIVAGLENDLLSTLSGHQFVNFSCCSYLNLDSHPRVIEGAIDAV
RRYGVLDHCIARSRVQLPVLKELEESLGELFQADVLSGVSASSISGGLLPLIASGHLGNGVRPLMIFDKHAHVSLAAAKP
ACADETEVVTCNYHDLEFIKDCCKKYQRVCYVVDGSDSLGGYAPVKELAELQDKYGLMVFYDDSHSISAYGERGIGYVRS
HSPALNENTVMVVTLNKAFGTSGAAILLNGYSQPMLRLVERFGGGLNYSQNLNTAAIGASLASAEIHRTAELPMLQKKLY
DNIALFDSLIPTEQSGNAYPIRLVPMSDETVISEGRQVIEAGFYVSPVFFPIVAKGTAGLRVMMRAGQTEDQIRRLCKIL
AEVRAPQ
>Mature_406_residues
TSRKKIMPTNQYRNNDKAIGIGNPFWDMSEQNGLAGIVAGLENDLLSTLSGHQFVNFSCCSYLNLDSHPRVIEGAIDAVR
RYGVLDHCIARSRVQLPVLKELEESLGELFQADVLSGVSASSISGGLLPLIASGHLGNGVRPLMIFDKHAHVSLAAAKPA
CADETEVVTCNYHDLEFIKDCCKKYQRVCYVVDGSDSLGGYAPVKELAELQDKYGLMVFYDDSHSISAYGERGIGYVRSH
SPALNENTVMVVTLNKAFGTSGAAILLNGYSQPMLRLVERFGGGLNYSQNLNTAAIGASLASAEIHRTAELPMLQKKLYD
NIALFDSLIPTEQSGNAYPIRLVPMSDETVISEGRQVIEAGFYVSPVFFPIVAKGTAGLRVMMRAGQTEDQIRRLCKILA
EVRAPQ

Specific function: Catalyzes the decarboxylative condensation of pimeloyl- CoA and L-alanine to produce 8-amino-7-oxononanoate (AON), coenzyme A and/or converts 2-amino-3-ketobutyrate to glycine and acetyl-CoA [H]

COG id: COG0156

COG function: function code H; 7-keto-8-aminopelargonate synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790046, Length=383, Percent_Identity=25.5874673629243, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786993, Length=360, Percent_Identity=25, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994529, Length=404, Percent_Identity=23.2673267326733, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320438, Length=372, Percent_Identity=24.4623655913978, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR004723
- InterPro:   IPR010962
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.3.1.29; =2.3.1.47 [H]

Molecular weight: Translated: 44314; Mature: 44183

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRKKIMPTNQYRNNDKAIGIGNPFWDMSEQNGLAGIVAGLENDLLSTLSGHQFVNFSC
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEH
CSYLNLDSHPRVIEGAIDAVRRYGVLDHCIARSRVQLPVLKELEESLGELFQADVLSGVS
HEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
ASSISGGLLPLIASGHLGNGVRPLMIFDKHAHVSLAAAKPACADETEVVTCNYHDLEFIK
CCCCCCCCHHHEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEECCCCHHHHH
DCCKKYQRVCYVVDGSDSLGGYAPVKELAELQDKYGLMVFYDDSHSISAYGERGIGYVRS
HHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCEECCCCCCCCEEEC
HSPALNENTVMVVTLNKAFGTSGAAILLNGYSQPMLRLVERFGGGLNYSQNLNTAAIGAS
CCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
LASAEIHRTAELPMLQKKLYDNIALFDSLIPTEQSGNAYPIRLVPMSDETVISEGRQVIE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
AGFYVSPVFFPIVAKGTAGLRVMMRAGQTEDQIRRLCKILAEVRAPQ
CCCCHHHHHHHHHCCCCCCHHHEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSRKKIMPTNQYRNNDKAIGIGNPFWDMSEQNGLAGIVAGLENDLLSTLSGHQFVNFSC
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEH
CSYLNLDSHPRVIEGAIDAVRRYGVLDHCIARSRVQLPVLKELEESLGELFQADVLSGVS
HEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
ASSISGGLLPLIASGHLGNGVRPLMIFDKHAHVSLAAAKPACADETEVVTCNYHDLEFIK
CCCCCCCCHHHEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEECCCCHHHHH
DCCKKYQRVCYVVDGSDSLGGYAPVKELAELQDKYGLMVFYDDSHSISAYGERGIGYVRS
HHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCEECCCCCCCCEEEC
HSPALNENTVMVVTLNKAFGTSGAAILLNGYSQPMLRLVERFGGGLNYSQNLNTAAIGAS
CCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHH
LASAEIHRTAELPMLQKKLYDNIALFDSLIPTEQSGNAYPIRLVPMSDETVISEGRQVIE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHH
AGFYVSPVFFPIVAKGTAGLRVMMRAGQTEDQIRRLCKILAEVRAPQ
CCCCHHHHHHHHHCCCCCCHHHEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA