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The map label for this gene is cmoA

Identifier: 157371026

GI number: 157371026

Start: 3064814

End: 3065557

Strand: Direct

Name: cmoA

Synonym: Spro_2786

Alternate gene names: 157371026

Gene position: 3064814-3065557 (Clockwise)

Preceding gene: 157371025

Following gene: 157371027

Centisome position: 56.25

GC content: 56.32

Gene sequence:

>744_bases
ATGCCAAACCGCGATACTCTTTTTTCTGCCCCAATCGCCAAACTGGGCGACTGGACCTTCGACGAACGCGTCGCTGAAGT
GTTCCCTGACATGATCCAGCGTTCCGTTCCCGGCTATTCCAATATCATTTCGATGATTGGCATGCTGGCCGAACGTTTCG
TTCAGCCCGACAGCCAGGTGTATGACCTCGGCTGTTCACTGGGCGCCGCAACGCTGTCGATGCGAAGGAATATCAAGGTG
GCGGGTTGTAACATCATTGCCGTCGACAATTCCCCGGCGATGGTGGAACGCTGCCGCCGCCATATTGACGCCTTCCGCGC
CGACACCCCGGTAGAAGTGATTGAGGCTGATATTCTCGATATCAAAATCGAAAATGCCTCGATGGTGGTGTTGAACTTCA
CCCTGCAATTCCTGGAGCCGGCCGACCGCCTGCGCCTGCTGGAACAGGTTTATCGCGGGCTGCGTCCGGGCGGCGCACTG
GTGCTGTCGGAGAAATTCAGTTTTGAAGATGCCGACGTCGGCGAGCTGCTGTTCAACATGCACCACGATTTTAAACGCGC
CAACGGCTACAGCGAACTGGAAATCAGCCAGAAGCGCAGCATGCTGGAAAACGTCATGCTGACCGACTCCGTAGCCGCCC
ACAAGACGCGTTTGAAGCAGGCCGGTTTTGAACACGCTGAAGTCTGGTTCCAGTGCTTTAACTTCGGTTCACTGATCGCC
CTGAAATCGGGGGCGGCAGCATGA

Upstream 100 bases:

>100_bases
CCCGCACCACCTCAGGCGGTTACGCCGCCTGCTTCCGCTGCTCTTTCTTGCCATTTTCTGTTAGCATATGCGCCTTCGAA
TTCTGAACTGATTTGCCGCC

Downstream 100 bases:

>100_bases
TTGAGTTTGGTGATTTTTATCAACGCATCGCAAAAGGCAACCTCAGCCATTGGCTCGATACGCTGCCCGCGCAGCTTAGC
GCCTGGCAGCGTGAGTCGCT

Product: putative methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MPNRDTLFSAPIAKLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPDSQVYDLGCSLGAATLSMRRNIKV
AGCNIIAVDNSPAMVERCRRHIDAFRADTPVEVIEADILDIKIENASMVVLNFTLQFLEPADRLRLLEQVYRGLRPGGAL
VLSEKFSFEDADVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVAAHKTRLKQAGFEHAEVWFQCFNFGSLIA
LKSGAAA

Sequences:

>Translated_247_residues
MPNRDTLFSAPIAKLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPDSQVYDLGCSLGAATLSMRRNIKV
AGCNIIAVDNSPAMVERCRRHIDAFRADTPVEVIEADILDIKIENASMVVLNFTLQFLEPADRLRLLEQVYRGLRPGGAL
VLSEKFSFEDADVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVAAHKTRLKQAGFEHAEVWFQCFNFGSLIA
LKSGAAA
>Mature_246_residues
PNRDTLFSAPIAKLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPDSQVYDLGCSLGAATLSMRRNIKVA
GCNIIAVDNSPAMVERCRRHIDAFRADTPVEVIEADILDIKIENASMVVLNFTLQFLEPADRLRLLEQVYRGLRPGGALV
LSEKFSFEDADVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVAAHKTRLKQAGFEHAEVWFQCFNFGSLIAL
KSGAAA

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=247, Percent_Identity=83.4008097165992, Blast_Score=436, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_SERP5 (A8GFJ7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479015.1
- ProteinModelPortal:   A8GFJ7
- SMR:   A8GFJ7
- STRING:   A8GFJ7
- GeneID:   5603948
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2786
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK2519555
- BioCyc:   SPRO399741:SPRO_2786-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27622; Mature: 27491

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: BINDING 39-39 BINDING 89-89 BINDING 132-132 BINDING 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNRDTLFSAPIAKLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPDSQV
CCCCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHH
YDLGCSLGAATLSMRRNIKVAGCNIIAVDNSPAMVERCRRHIDAFRADTPVEVIEADILD
HHHHHHHHHHHHHHHCCEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEE
IKIENASMVVLNFTLQFLEPADRLRLLEQVYRGLRPGGALVLSEKFSFEDADVGELLFNM
EEECCCCEEEEEHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHH
HHDFKRANGYSELEISQKRSMLENVMLTDSVAAHKTRLKQAGFEHAEVWFQCFNFGSLIA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEE
LKSGAAA
ECCCCCC
>Mature Secondary Structure 
PNRDTLFSAPIAKLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPDSQV
CCCCCCHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHH
YDLGCSLGAATLSMRRNIKVAGCNIIAVDNSPAMVERCRRHIDAFRADTPVEVIEADILD
HHHHHHHHHHHHHHHCCEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHEE
IKIENASMVVLNFTLQFLEPADRLRLLEQVYRGLRPGGALVLSEKFSFEDADVGELLFNM
EEECCCCEEEEEHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHH
HHDFKRANGYSELEISQKRSMLENVMLTDSVAAHKTRLKQAGFEHAEVWFQCFNFGSLIA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEE
LKSGAAA
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA