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The map label for this gene is minC

Identifier: 157370996

GI number: 157370996

Start: 3036021

End: 3036722

Strand: Direct

Name: minC

Synonym: Spro_2756

Alternate gene names: 157370996

Gene position: 3036021-3036722 (Clockwise)

Preceding gene: 157370992

Following gene: 157370997

Centisome position: 55.72

GC content: 54.27

Gene sequence:

>702_bases
ATGTCACAATCGCCAATTGAGCTAAAAGGCAGCAGTTTTACCCTATCGGTTGTTCATTTGTATAATTCGGAACCCGAGGT
AATACGTCAGGCGTTACAAGAAAAAGTCGAGCAAGCGCCCGCTTTTTTGAAAAATGCCCCTGTTGTTATCAACGTTGCAA
CGCTGAACGGCGACGCAAACTGGAAAGAACTTCAACAGGCTGTCACGGCAGCAGGGCTGCGCGTTGTGGGTATCAGCGGT
TGCAGAGATGAGCGGCAAAAACGTGCAATAGCCCGTGCCGGGCTGCCGTTATTGAACGAAGGCAAAGGCCAGAAGATGGC
TACCCCGGAACCGGCGCCCGCGCCAGCCCCGGTGGTGGATCCCAACGCCCCCGCCAAGACGCGCATCATCAGTACCCCTG
TTCGTTCCGGCCAACAGATTTATGCCCGCAACAGCGATCTGATCGTGACCAGCAGCGTCAGCGCCGGCGCTGAATTAATT
GCCGATGGCAATATTCACGTTTACGGCATGATGCGCGGTCGTGCGCTGGCTGGTGCTTCAGGTGATACGCAGTGCCAGAT
TTTTTGCACGCACCTGGGTGCTGAGCTAGTCTCTATCGCAGGGCAGTACTGGTTGAGCGACCAAATCCCGTCCGACTTTG
TCGGGCAGGCTGTACGACTCAGCCTGTTGGATAACGCTTTAACCATACAACCTTTAAATTAA

Upstream 100 bases:

>100_bases
TGGATATAACTCTGACTATAACATGCTTATAGTACTTCGGAATATCGCACCCCGATTGGTATTCCGGGGATTTAAAGTTG
CTGAGACTGAGTCAGGATAG

Downstream 100 bases:

>100_bases
GCCCTTTTGACAAGGAATCCATTTCATGGCACGCATTATTGTTGTTACATCGGGTAAAGGGGGCGTTGGCAAGACCACTT
CAAGCGCGGCCATCGCTACC

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSQSPIELKGSSFTLSVVHLYNSEPEVIRQALQEKVEQAPAFLKNAPVVINVATLNGDANWKELQQAVTAAGLRVVGISG
CRDERQKRAIARAGLPLLNEGKGQKMATPEPAPAPAPVVDPNAPAKTRIISTPVRSGQQIYARNSDLIVTSSVSAGAELI
ADGNIHVYGMMRGRALAGASGDTQCQIFCTHLGAELVSIAGQYWLSDQIPSDFVGQAVRLSLLDNALTIQPLN

Sequences:

>Translated_233_residues
MSQSPIELKGSSFTLSVVHLYNSEPEVIRQALQEKVEQAPAFLKNAPVVINVATLNGDANWKELQQAVTAAGLRVVGISG
CRDERQKRAIARAGLPLLNEGKGQKMATPEPAPAPAPVVDPNAPAKTRIISTPVRSGQQIYARNSDLIVTSSVSAGAELI
ADGNIHVYGMMRGRALAGASGDTQCQIFCTHLGAELVSIAGQYWLSDQIPSDFVGQAVRLSLLDNALTIQPLN
>Mature_232_residues
SQSPIELKGSSFTLSVVHLYNSEPEVIRQALQEKVEQAPAFLKNAPVVINVATLNGDANWKELQQAVTAAGLRVVGISGC
RDERQKRAIARAGLPLLNEGKGQKMATPEPAPAPAPVVDPNAPAKTRIISTPVRSGQQIYARNSDLIVTSSVSAGAELIA
DGNIHVYGMMRGRALAGASGDTQCQIFCTHLGAELVSIAGQYWLSDQIPSDFVGQAVRLSLLDNALTIQPLN

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=234, Percent_Identity=66.6666666666667, Blast_Score=320, Evalue=5e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_SERP5 (A8GFG7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478985.1
- ProteinModelPortal:   A8GFG7
- STRING:   A8GFG7
- GeneID:   5607198
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2756
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- OMA:   IFCTHLA
- ProtClustDB:   PRK03511
- BioCyc:   SPRO399741:SPRO_2756-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 24733; Mature: 24601

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSPIELKGSSFTLSVVHLYNSEPEVIRQALQEKVEQAPAFLKNAPVVINVATLNGDAN
CCCCCCEECCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
WKELQQAVTAAGLRVVGISGCRDERQKRAIARAGLPLLNEGKGQKMATPEPAPAPAPVVD
HHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PNAPAKTRIISTPVRSGQQIYARNSDLIVTSSVSAGAELIADGNIHVYGMMRGRALAGAS
CCCCCCEEEEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCCEEEEEEEECCEEECCC
GDTQCQIFCTHLGAELVSIAGQYWLSDQIPSDFVGQAVRLSLLDNALTIQPLN
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEECCCEEEEEECC
>Mature Secondary Structure 
SQSPIELKGSSFTLSVVHLYNSEPEVIRQALQEKVEQAPAFLKNAPVVINVATLNGDAN
CCCCCEECCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
WKELQQAVTAAGLRVVGISGCRDERQKRAIARAGLPLLNEGKGQKMATPEPAPAPAPVVD
HHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PNAPAKTRIISTPVRSGQQIYARNSDLIVTSSVSAGAELIADGNIHVYGMMRGRALAGAS
CCCCCCEEEEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCCEEEEEEEECCEEECCC
GDTQCQIFCTHLGAELVSIAGQYWLSDQIPSDFVGQAVRLSLLDNALTIQPLN
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA