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The map label for this gene is smvA [H]

Identifier: 157370927

GI number: 157370927

Start: 2957421

End: 2958935

Strand: Direct

Name: smvA [H]

Synonym: Spro_2687

Alternate gene names: 157370927

Gene position: 2957421-2958935 (Clockwise)

Preceding gene: 157370925

Following gene: 157370928

Centisome position: 54.28

GC content: 57.1

Gene sequence:

>1515_bases
ATGGCAACGCATCCGCGTCGCCTGCTTTTTTGGAATAATATTATGCACGCAAACAACCGCTGGTTGATCCTGGCAATGAT
CTCCAGCGCGCTATTTTTGATCATTATCGATATGACGGTGCTATACACCGCATTGCCACGGCTGACCCAGGCGCTGGACG
CCAGCGCCTCGCAAAAATTATGGATTGTGAATGCCTACCCGCTAGTGGTCGCCGGTTTACTGCCCGGTGCGGGCATGCTG
AGCGATCGCATTGGTCATAAACGGCTGTTTATGGCCGGATTGCCGGTGTTTGCCGTCGCCTCCCTTTGTGCCGCCTTTTC
TCCTTCAGCCCAATGGCTGATCGCCGCCCGCGTATTCCTCGCGGTAGGTGCAGCGATGATGATGCCTGCAACCCTGTCCA
TTGTCCGCCATGTGTTTACCGACGAACGTGAACGCGCCCTGGCGATTGGCATTTGGGCCGCAGTCGCGTCCGGTGGTGCC
GCTATCGGCCCGGTGGTCGGTGGAGTCTTGCTGGAGTATTTCTGGTGGGGATCGGTATTTTTGATCAACGTCCCTGTCGT
CATGGTGGTGCTGCCGCTGGCCTGGCGATTGATACCGCACTGCGGTGGGGAAAATAAACGCCCTTACGATATCATCGGGT
CAGTGCAGATCATGGCCGGTCTGGTGGGTAGCATCTATGCCCTGAAGGAGCTGAGCAAAACAACGCCCTCCATTTCTGCG
CTGGCAATCGCCGCCACCATTGGCATTTTGTCGCTCTGGCTGTTTGTTCGTCGACAGCGTCGGGCCCGTTATCCGATGAT
CGACTTCTCACTATTTCAGAATCGGCTGTTTGCCGGCGGCGTCGGCGTGGCTCTGGTGTCGATGGTTGCGTTAGTCGGTG
TGGAACTGGTACTGACTCAACGCCTGCAACTGGTGCTTGAGCTGAGTCCATTACAGGCCGCGCTGTTTATTCTGCCGATC
CCGGTGGCCTCCGCACTGGCCGGTCCGCTGGCCGGTTTACTGCTGCCGCGTTACGGCGAGCGCAACATGATATTCGGTGG
ATTGTTCCTGACCGGCCTGGGCATTGCCGGGCTGGCCCTGCTTTACCAGAACAGCCTGATGTCGCAGTTGGTTTGTCTGT
TTATCGCCGGTTTTGGCATCGGTGGTGCCATTACCGCCGCGTCAACCGCCATCATGCTCAACGCTCCGGAAGAAAAATCC
GGTATGGCTGCCTCGATCGAGGATGTGTCCTATGAGCTGGGTGGCGTGCTCGGTATTACCTTGCTGGGTGGATTGATGAC
CGCCATCTATAGCCACAGCCTGGTGTTACCCGACAATCTGCCGGTGGGCGATGTCGCTTACGACAGCATTGATGAAGCCC
TGCGGCTGGCTGCCAATCTGGCTGTCGAACAGGCTGAACAACTGAGAAAACTGGCTCGGCTGGCTTTCGACCGAGCATTT
ATCGCGGTGTTGATTGCAGCAGCATTACTGATGGCGCTAAGCGCCGGCGTGGCAAAATTGGTCTTACGCAAGTAA

Upstream 100 bases:

>100_bases
ATGCTCCGTTGACGTCCCATTGAGAAACCCTCTTTTCAATACATACGTATGGATATATATTACGCCAGTATACCACCCGG
CGCGTTCGGGTGGTGACCTT

Downstream 100 bases:

>100_bases
TGATACCAAGCCGCTGTTGTTGTTAACGCATTCTGCTTACACTGAATGGGCAATTTGCTTGTCGGATTTATCGTTATCGG
TTTCAGCAATTGCATTGATG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MATHPRRLLFWNNIMHANNRWLILAMISSALFLIIIDMTVLYTALPRLTQALDASASQKLWIVNAYPLVVAGLLPGAGML
SDRIGHKRLFMAGLPVFAVASLCAAFSPSAQWLIAARVFLAVGAAMMMPATLSIVRHVFTDERERALAIGIWAAVASGGA
AIGPVVGGVLLEYFWWGSVFLINVPVVMVVLPLAWRLIPHCGGENKRPYDIIGSVQIMAGLVGSIYALKELSKTTPSISA
LAIAATIGILSLWLFVRRQRRARYPMIDFSLFQNRLFAGGVGVALVSMVALVGVELVLTQRLQLVLELSPLQAALFILPI
PVASALAGPLAGLLLPRYGERNMIFGGLFLTGLGIAGLALLYQNSLMSQLVCLFIAGFGIGGAITAASTAIMLNAPEEKS
GMAASIEDVSYELGGVLGITLLGGLMTAIYSHSLVLPDNLPVGDVAYDSIDEALRLAANLAVEQAEQLRKLARLAFDRAF
IAVLIAAALLMALSAGVAKLVLRK

Sequences:

>Translated_504_residues
MATHPRRLLFWNNIMHANNRWLILAMISSALFLIIIDMTVLYTALPRLTQALDASASQKLWIVNAYPLVVAGLLPGAGML
SDRIGHKRLFMAGLPVFAVASLCAAFSPSAQWLIAARVFLAVGAAMMMPATLSIVRHVFTDERERALAIGIWAAVASGGA
AIGPVVGGVLLEYFWWGSVFLINVPVVMVVLPLAWRLIPHCGGENKRPYDIIGSVQIMAGLVGSIYALKELSKTTPSISA
LAIAATIGILSLWLFVRRQRRARYPMIDFSLFQNRLFAGGVGVALVSMVALVGVELVLTQRLQLVLELSPLQAALFILPI
PVASALAGPLAGLLLPRYGERNMIFGGLFLTGLGIAGLALLYQNSLMSQLVCLFIAGFGIGGAITAASTAIMLNAPEEKS
GMAASIEDVSYELGGVLGITLLGGLMTAIYSHSLVLPDNLPVGDVAYDSIDEALRLAANLAVEQAEQLRKLARLAFDRAF
IAVLIAAALLMALSAGVAKLVLRK
>Mature_503_residues
ATHPRRLLFWNNIMHANNRWLILAMISSALFLIIIDMTVLYTALPRLTQALDASASQKLWIVNAYPLVVAGLLPGAGMLS
DRIGHKRLFMAGLPVFAVASLCAAFSPSAQWLIAARVFLAVGAAMMMPATLSIVRHVFTDERERALAIGIWAAVASGGAA
IGPVVGGVLLEYFWWGSVFLINVPVVMVVLPLAWRLIPHCGGENKRPYDIIGSVQIMAGLVGSIYALKELSKTTPSISAL
AIAATIGILSLWLFVRRQRRARYPMIDFSLFQNRLFAGGVGVALVSMVALVGVELVLTQRLQLVLELSPLQAALFILPIP
VASALAGPLAGLLLPRYGERNMIFGGLFLTGLGIAGLALLYQNSLMSQLVCLFIAGFGIGGAITAASTAIMLNAPEEKSG
MAASIEDVSYELGGVLGITLLGGLMTAIYSHSLVLPDNLPVGDVAYDSIDEALRLAANLAVEQAEQLRKLARLAFDRAFI
AVLIAAALLMALSAGVAKLVLRK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=385, Percent_Identity=27.7922077922078, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1790195, Length=399, Percent_Identity=29.8245614035088, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788710, Length=495, Percent_Identity=23.4343434343434, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789042, Length=406, Percent_Identity=23.3990147783251, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788392, Length=413, Percent_Identity=25.4237288135593, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324954, Length=383, Percent_Identity=24.2819843342037, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6322958, Length=473, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=337, Percent_Identity=24.9258160237389, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53661; Mature: 53530

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATHPRRLLFWNNIMHANNRWLILAMISSALFLIIIDMTVLYTALPRLTQALDASASQKL
CCCCCCHHHEECCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
WIVNAYPLVVAGLLPGAGMLSDRIGHKRLFMAGLPVFAVASLCAAFSPSAQWLIAARVFL
EEEECHHHHHHHHCCCCCHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHH
AVGAAMMMPATLSIVRHVFTDERERALAIGIWAAVASGGAAIGPVVGGVLLEYFWWGSVF
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
LINVPVVMVVLPLAWRLIPHCGGENKRPYDIIGSVQIMAGLVGSIYALKELSKTTPSISA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAIAATIGILSLWLFVRRQRRARYPMIDFSLFQNRLFAGGVGVALVSMVALVGVELVLTQ
HHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RLQLVLELSPLQAALFILPIPVASALAGPLAGLLLPRYGERNMIFGGLFLTGLGIAGLAL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
LYQNSLMSQLVCLFIAGFGIGGAITAASTAIMLNAPEEKSGMAASIEDVSYELGGVLGIT
HHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHH
LLGGLMTAIYSHSLVLPDNLPVGDVAYDSIDEALRLAANLAVEQAEQLRKLARLAFDRAF
HHHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVLIAAALLMALSAGVAKLVLRK
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATHPRRLLFWNNIMHANNRWLILAMISSALFLIIIDMTVLYTALPRLTQALDASASQKL
CCCCCHHHEECCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE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HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7926834; 11677609 [H]