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The map label for this gene is trpD

Identifier: 157370909

GI number: 157370909

Start: 2938902

End: 2939900

Strand: Direct

Name: trpD

Synonym: Spro_2669

Alternate gene names: 157370909

Gene position: 2938902-2939900 (Clockwise)

Preceding gene: 157370908

Following gene: 157370910

Centisome position: 53.94

GC content: 59.96

Gene sequence:

>999_bases
ATGCAAACTATTCTTGAAAAACTGTACCGTTCAGAGTCGATGAACCAGCAGGAGAGCCAGCAGTTATTCAGCGCCATCGT
GCGCGGTGAACTGGAGCCAAGCCAACTGGCCGCCGCACTGATCAGCATGAAGATCCGCGGCGAACACCCGGAAGAGATCG
CCGGTGCAGCCAAAGCGCTGCTGGCCGATGCCCTGCCGTTCCCGCGCCCGGATTACCCCTTTGCCGATATCGTCGGCACC
GGGGGTGACGGCACCAACAGTATTAATATCTCCACCGCCAGCGCCTTTGTGGCGGCGGCGTGTGGCGCCAAAGTGGCCAA
ACACGGCAACCGTAGCGTTTCCAGCCGCTCGGGTTCATCGGATCTGCTGGCAGCATTTGGCATTCGCCTGGATTTGCCGG
CAGAAGAAGCACGTAAGGCACTGGACGAACTGGGCGTGTGCTTCCTGTTCGCCCCGCAGTACCACACCGGTTTCCGCCAT
GCGATGCCGGTACGCCAGCAGTTGAAAACCCGCACGGTGTTCAACGTGCTCGGCCCGTTGATCAACCCGGCACGTCCACC
GCTGGCGCTGATCGGCGTTTACAGCCCGGAACTGGTGTTGCCGATTGCCGAAACCCTGCGCGTACTGGGTTATCAACGGG
CGGCCGTGGTGCACGGCGGCGGTATGGACGAAGTGGCGATCCATGCAACGACCCACGTGGCCGAGCTGAACAACGGCGAA
ATTGAAAGCTATCAGTTGACGCCTCAGTCCTTCGGATTGCAAAGCTATCCGCTGGAAGCCCTGCTGGGCGGCTCACCGGA
AGAAAATCGTGACATTCTGGCAAGGTTGTTACAAGGTAAAGGTGACCCGGCGCACGCCGCTGCGGTAGCCGCTAATGTGG
CGCTGCTGCTGAAGTTATTCGGGCATGAAGACCTGCGCCAAAATGCGCAGCAGGCACTGGACATGATTCACAGCGGGCAG
GCTTACGAGCGTGTCACCGCACTGGCAGCAAGAGGATAA

Upstream 100 bases:

>100_bases
TTTCCAGTTCCATCCGGAATCGATCCTGACCACCCATGGCGCGCGTTTGCTTGAGCAGACTCTGGCCTGGGCGCTGGCGA
AATAACGAGGGGAAACGACG

Downstream 100 bases:

>100_bases
ATGATGCAGGAAACCGTGCTCAACAAGATTGTTCGTGACAAAGCGCAATGGGTCGCGGCACGACAGCAACAACAGCCACT
GGCCAGTTTTCAAAATGAAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQTILEKLYRSESMNQQESQQLFSAIVRGELEPSQLAAALISMKIRGEHPEEIAGAAKALLADALPFPRPDYPFADIVGT
GGDGTNSINISTASAFVAAACGAKVAKHGNRSVSSRSGSSDLLAAFGIRLDLPAEEARKALDELGVCFLFAPQYHTGFRH
AMPVRQQLKTRTVFNVLGPLINPARPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHGGGMDEVAIHATTHVAELNNGE
IESYQLTPQSFGLQSYPLEALLGGSPEENRDILARLLQGKGDPAHAAAVAANVALLLKLFGHEDLRQNAQQALDMIHSGQ
AYERVTALAARG

Sequences:

>Translated_332_residues
MQTILEKLYRSESMNQQESQQLFSAIVRGELEPSQLAAALISMKIRGEHPEEIAGAAKALLADALPFPRPDYPFADIVGT
GGDGTNSINISTASAFVAAACGAKVAKHGNRSVSSRSGSSDLLAAFGIRLDLPAEEARKALDELGVCFLFAPQYHTGFRH
AMPVRQQLKTRTVFNVLGPLINPARPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHGGGMDEVAIHATTHVAELNNGE
IESYQLTPQSFGLQSYPLEALLGGSPEENRDILARLLQGKGDPAHAAAVAANVALLLKLFGHEDLRQNAQQALDMIHSGQ
AYERVTALAARG
>Mature_332_residues
MQTILEKLYRSESMNQQESQQLFSAIVRGELEPSQLAAALISMKIRGEHPEEIAGAAKALLADALPFPRPDYPFADIVGT
GGDGTNSINISTASAFVAAACGAKVAKHGNRSVSSRSGSSDLLAAFGIRLDLPAEEARKALDELGVCFLFAPQYHTGFRH
AMPVRQQLKTRTVFNVLGPLINPARPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHGGGMDEVAIHATTHVAELNNGE
IESYQLTPQSFGLQSYPLEALLGGSPEENRDILARLLQGKGDPAHAAAVAANVALLLKLFGHEDLRQNAQQALDMIHSGQ
AYERVTALAARG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=332, Percent_Identity=79.8192771084337, Blast_Score=505, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6320561, Length=356, Percent_Identity=33.1460674157303, Blast_Score=139, Evalue=8e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_SERP5 (A8GF80)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478898.1
- ProteinModelPortal:   A8GF80
- SMR:   A8GF80
- STRING:   A8GF80
- GeneID:   5605971
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2669
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   SPRO399741:SPRO_2669-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35442; Mature: 35442

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTILEKLYRSESMNQQESQQLFSAIVRGELEPSQLAAALISMKIRGEHPEEIAGAAKAL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LADALPFPRPDYPFADIVGTGGDGTNSINISTASAFVAAACGAKVAKHGNRSVSSRSGSS
HHHCCCCCCCCCCHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DLLAAFGIRLDLPAEEARKALDELGVCFLFAPQYHTGFRHAMPVRQQLKTRTVFNVLGPL
HHHHHHCCEEECCHHHHHHHHHHCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
INPARPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHGGGMDEVAIHATTHVAELNNGE
CCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEEHHHHEECCCCC
IESYQLTPQSFGLQSYPLEALLGGSPEENRDILARLLQGKGDPAHAAAVAANVALLLKLF
CEEEEECHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GHEDLRQNAQQALDMIHSGQAYERVTALAARG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQTILEKLYRSESMNQQESQQLFSAIVRGELEPSQLAAALISMKIRGEHPEEIAGAAKAL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LADALPFPRPDYPFADIVGTGGDGTNSINISTASAFVAAACGAKVAKHGNRSVSSRSGSS
HHHCCCCCCCCCCHHHEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
DLLAAFGIRLDLPAEEARKALDELGVCFLFAPQYHTGFRHAMPVRQQLKTRTVFNVLGPL
HHHHHHCCEEECCHHHHHHHHHHCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHH
INPARPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHGGGMDEVAIHATTHVAELNNGE
CCCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHEEEECCCCCCEEEEEHHHHEECCCCC
IESYQLTPQSFGLQSYPLEALLGGSPEENRDILARLLQGKGDPAHAAAVAANVALLLKLF
CEEEEECHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GHEDLRQNAQQALDMIHSGQAYERVTALAARG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA