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The map label for this gene is sapB [H]

Identifier: 157370870

GI number: 157370870

Start: 2894293

End: 2895258

Strand: Direct

Name: sapB [H]

Synonym: Spro_2630

Alternate gene names: 157370870

Gene position: 2894293-2895258 (Clockwise)

Preceding gene: 157370869

Following gene: 157370871

Centisome position: 53.12

GC content: 57.76

Gene sequence:

>966_bases
GTGATTATCTTTACCTTACGCCGTTGCCTGCTGCTGCTGATCACGCTGTTCTTCCTGACGCTGGTCAGCTTTAGCCTGAG
CTATTTCACACCGCGCGCTCCGCTGAACGGTGCCGCCCTGCTGGATGCCTACCAGTTTTACTTTGTCAGCCTGTTGCACT
GGGATTTTGGCGTTTCCAGCATTAACGGTCAGGCCATCAGCGAACAACTTCGTGAAGTGTTCCCGGCGACCATGGAGCTG
TGCATTCTGGCGTTCACCATGGCGTTATTTATCGGCATTCCCCTGGGGATTATTGCCGGCGTGATGCGCGGCAAATGGCA
GGACACCGCCATCAGTACCTTTGCGCTGCTCGGTTTCTCGATGCCGGTGTTCTGGCTGGCGCTGCTGCTGATGCTGTTTT
TCTCGCTGCACCTCGGCTGGCTGCCGGTTTCCGGCCGTTTCGATCTGCTGTATCAGGTTAAGCCGATCACCGGCTTTGCC
CTGATTGACGCCTGGCTGTCCGATTCGCCCTATCGCAGCGAAATGATTGGCAGCGCGCTACGCCATATGATCCTGCCGAT
TGCCGCGCTGGCAGTGGCACCTACCACCGAGGTGGTGCGACTGATGCGTATCAGCACCGACGATGTGCTCAACCAGAACT
ACATTAAGGCCGCCGCGACCCGTGGGCTTTCCCGTTTCACCATTATCCGTCGCCACGTGCTGCACAATGCACTGCCACCG
ATCGTGCCCAAACTGGGCCTGCAGTTCTCCACCATGCTGACGCTGGCGATGATCACCGAAGTGGTGTTCAGTTGGCCGGG
CCTCGGGCGCTGGATGATTAACGCCATCCGCCAGCAGGATTACGCGGCGATCTCCGCCGGTGTAATGGTGGTGGGCACGC
TGGTGATCACCATTAACGTGCTGGCCGATATCTTGGGCGCTGCCACCAACCCACTGAAACATAAGGAATGGTATGCCCTT
AGATAA

Upstream 100 bases:

>100_bases
TGCAGGCCTATCGTTACGACATTAAGGGACTGGTTCTGAGCCCGTTCGGCAATGCGTCATTTGCCGGCGTGTTCCGTGAA
TCTGCCCAGGGGCCGAAAAA

Downstream 100 bases:

>100_bases
CGTATACCGCGAAAAGAAAATGCCGAGTCCGCTGCTCTACACCTGGCGGATTTTTTACGGTGATGCGCTGGCGATGATTG
GTTTCTACGGCGTGATAGCG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIIFTLRRCLLLLITLFFLTLVSFSLSYFTPRAPLNGAALLDAYQFYFVSLLHWDFGVSSINGQAISEQLREVFPATMEL
CILAFTMALFIGIPLGIIAGVMRGKWQDTAISTFALLGFSMPVFWLALLLMLFFSLHLGWLPVSGRFDLLYQVKPITGFA
LIDAWLSDSPYRSEMIGSALRHMILPIAALAVAPTTEVVRLMRISTDDVLNQNYIKAAATRGLSRFTIIRRHVLHNALPP
IVPKLGLQFSTMLTLAMITEVVFSWPGLGRWMINAIRQQDYAAISAGVMVVGTLVITINVLADILGAATNPLKHKEWYAL
R

Sequences:

>Translated_321_residues
MIIFTLRRCLLLLITLFFLTLVSFSLSYFTPRAPLNGAALLDAYQFYFVSLLHWDFGVSSINGQAISEQLREVFPATMEL
CILAFTMALFIGIPLGIIAGVMRGKWQDTAISTFALLGFSMPVFWLALLLMLFFSLHLGWLPVSGRFDLLYQVKPITGFA
LIDAWLSDSPYRSEMIGSALRHMILPIAALAVAPTTEVVRLMRISTDDVLNQNYIKAAATRGLSRFTIIRRHVLHNALPP
IVPKLGLQFSTMLTLAMITEVVFSWPGLGRWMINAIRQQDYAAISAGVMVVGTLVITINVLADILGAATNPLKHKEWYAL
R
>Mature_321_residues
MIIFTLRRCLLLLITLFFLTLVSFSLSYFTPRAPLNGAALLDAYQFYFVSLLHWDFGVSSINGQAISEQLREVFPATMEL
CILAFTMALFIGIPLGIIAGVMRGKWQDTAISTFALLGFSMPVFWLALLLMLFFSLHLGWLPVSGRFDLLYQVKPITGFA
LIDAWLSDSPYRSEMIGSALRHMILPIAALAVAPTTEVVRLMRISTDDVLNQNYIKAAATRGLSRFTIIRRHVLHNALPP
IVPKLGLQFSTMLTLAMITEVVFSWPGLGRWMINAIRQQDYAAISAGVMVVGTLVITINVLADILGAATNPLKHKEWYAL
R

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=321, Percent_Identity=79.1277258566978, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1789965, Length=344, Percent_Identity=36.3372093023256, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787053, Length=337, Percent_Identity=30.2670623145401, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787761, Length=307, Percent_Identity=36.4820846905537, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789888, Length=278, Percent_Identity=31.6546762589928, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787497, Length=331, Percent_Identity=29.3051359516616, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788504, Length=261, Percent_Identity=25.6704980842912, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35784; Mature: 35784

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFTLRRCLLLLITLFFLTLVSFSLSYFTPRAPLNGAALLDAYQFYFVSLLHWDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
INGQAISEQLREVFPATMELCILAFTMALFIGIPLGIIAGVMRGKWQDTAISTFALLGFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MPVFWLALLLMLFFSLHLGWLPVSGRFDLLYQVKPITGFALIDAWLSDSPYRSEMIGSAL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHH
RHMILPIAALAVAPTTEVVRLMRISTDDVLNQNYIKAAATRGLSRFTIIRRHVLHNALPP
HHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
IVPKLGLQFSTMLTLAMITEVVFSWPGLGRWMINAIRQQDYAAISAGVMVVGTLVITINV
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADILGAATNPLKHKEWYALR
HHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIIFTLRRCLLLLITLFFLTLVSFSLSYFTPRAPLNGAALLDAYQFYFVSLLHWDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
INGQAISEQLREVFPATMELCILAFTMALFIGIPLGIIAGVMRGKWQDTAISTFALLGFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MPVFWLALLLMLFFSLHLGWLPVSGRFDLLYQVKPITGFALIDAWLSDSPYRSEMIGSAL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHH
RHMILPIAALAVAPTTEVVRLMRISTDDVLNQNYIKAAATRGLSRFTIIRRHVLHNALPP
HHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
IVPKLGLQFSTMLTLAMITEVVFSWPGLGRWMINAIRQQDYAAISAGVMVVGTLVITINV
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADILGAATNPLKHKEWYALR
HHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]