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The map label for this gene is umuD [H]

Identifier: 157370845

GI number: 157370845

Start: 2868535

End: 2868957

Strand: Direct

Name: umuD [H]

Synonym: Spro_2605

Alternate gene names: 157370845

Gene position: 2868535-2868957 (Clockwise)

Preceding gene: 157370844

Following gene: 157370846

Centisome position: 52.64

GC content: 55.79

Gene sequence:

>423_bases
ATGAAACACTTTTTCCCCACGCCAACCCCAGAGAAACAGTTCATTCCGCTTTACGCCGATAACGTCCCGGCGGGCTTTCC
CAGCCCGGCGCAAGACTATATACACGCGCGAATCGACCTCAACGAGTACTGCATTAGCCACCCTTCGGCGACTTACTTTC
TGATCGCTTCAGGAGAAAGCATGATCGAAGCCGGGATCACCGACGGCTCCATGCTGGTGGTCGATCGCAGTATTGGCGCC
TGTCACGGCGATATCGTGATCGCCAGCATCGCAGGCGAGTTCACGGTTAAGCGCCTGTGCCTGCATCCTGTCAAACAGCT
TGAGCCGATGAACCCGACATTCAGGCCGATACCGCTCCCGGATGATGGTGCTGAACTGGACATTGTCGGCGTGGTGGTTT
CAACCATCACCAGGCTGAAATAA

Upstream 100 bases:

>100_bases
AGGGGATAGCTGTGGATCCTCTCGCCCCTGACTTTCTTTATGGTTGTAATGGCTAAAACTCGCTTATACTGTATATAAAA
ACAGTATAGAGAAATGCACC

Downstream 100 bases:

>100_bases
TGTACGCCCTGGCCGATGTAAACAACTTCTATGCAAGTTGTGAAACGCTGTGGCGTCCGGATCTGCGTGGCCGCCCGATT
GTTGTTCTGTCGAACAACGA

Product: peptidase S24/S26 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKHFFPTPTPEKQFIPLYADNVPAGFPSPAQDYIHARIDLNEYCISHPSATYFLIASGESMIEAGITDGSMLVVDRSIGA
CHGDIVIASIAGEFTVKRLCLHPVKQLEPMNPTFRPIPLPDDGAELDIVGVVVSTITRLK

Sequences:

>Translated_140_residues
MKHFFPTPTPEKQFIPLYADNVPAGFPSPAQDYIHARIDLNEYCISHPSATYFLIASGESMIEAGITDGSMLVVDRSIGA
CHGDIVIASIAGEFTVKRLCLHPVKQLEPMNPTFRPIPLPDDGAELDIVGVVVSTITRLK
>Mature_140_residues
MKHFFPTPTPEKQFIPLYADNVPAGFPSPAQDYIHARIDLNEYCISHPSATYFLIASGESMIEAGITDGSMLVVDRSIGA
CHGDIVIASIAGEFTVKRLCLHPVKQLEPMNPTFRPIPLPDDGAELDIVGVVVSTITRLK

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=139, Percent_Identity=50.3597122302158, Blast_Score=143, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15264; Mature: 15264

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFFPTPTPEKQFIPLYADNVPAGFPSPAQDYIHARIDLNEYCISHPSATYFLIASGES
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHEEEEECCHHHHHCCCCCEEEEEECCCH
MIEAGITDGSMLVVDRSIGACHGDIVIASIAGEFTVKRLCLHPVKQLEPMNPTFRPIPLP
HEECCCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DDGAELDIVGVVVSTITRLK
CCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKHFFPTPTPEKQFIPLYADNVPAGFPSPAQDYIHARIDLNEYCISHPSATYFLIASGES
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHEEEEECCHHHHHCCCCCEEEEEECCCH
MIEAGITDGSMLVVDRSIGACHGDIVIASIAGEFTVKRLCLHPVKQLEPMNPTFRPIPLP
HEECCCCCCEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DDGAELDIVGVVVSTITRLK
CCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609; 1910151 [H]