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The map label for this gene is moeB [H]

Identifier: 157369789

GI number: 157369789

Start: 1684870

End: 1685625

Strand: Reverse

Name: moeB [H]

Synonym: Spro_1546

Alternate gene names: 157369789

Gene position: 1685625-1684870 (Counterclockwise)

Preceding gene: 157369790

Following gene: 157369787

Centisome position: 30.94

GC content: 58.99

Gene sequence:

>756_bases
ATGCTGCCGGAATTAACCGATGCCGAAACATTGCGCTATAACCGCCAGATTATCCTGCGTGGTTTCGACTTCGACGGTCA
GGAAAAGCTGAAAGCCGCACGGGTAATGATTGTTGGCCTGGGTGGCTTGGGTTGCGCCGCCGCGCCCTATTTGGCTGCCG
CAGGGGTGGGTCATCTGACGCTGGTTGATTTCGACACCGTTTCGCTCTCCAACCTGCAACGCCAGATCCTGCACCGCGAC
GCGCGCATTGGCATGGCGAAGGTTGATTCGGCGCGTATCGAACTGAGCGCCATCAATCCGCATATCCATATTGATGCCGT
TGACCGGCAACTGGACGATGAACAGATGGCGGCACAGATTGCCGCCAACGATCTGGTGCTGGACTGTACCGACAACGTGG
CAACGCGCGATCTGCTCAACCGCCTGTGCCATGCGCAGCGCAAACCGCTGGTGTCCGGCGCGGCGATCCGTATGGAAGGG
CAACTCAGCGTCTTCACTTACCAGGCCAATGAACCTTGCTACCGCTGCCTGAGCCGGTTATTCGGTGATAACGCCCTGAC
CTGCGTCGAGGCCGGTGTGATGGCACCGCTGGTGGGCACCATCGGCACTCTGCAGGCTATCGAGGCTATCAAACTGCTGA
CGCAATACGGCCAGCCGCTTACCGGCAAACTGCTGATGTTTGACGCCATGACGATGCAGTTCCGTGAGATGAAGCTGCCG
AAGGATCCGCAGTGCGAGGTGTGTGGCGGGGAATAG

Upstream 100 bases:

>100_bases
AGGGTAACTGTTTTATCGTACTGGAGCGCGATCGCGGTTCCGTAGCGGTGGGTGAAAAGGTGGAAATTGAGCCTTTCAAC
GCCCTGCTGAGGAGCTAAGC

Downstream 100 bases:

>100_bases
CAGACACAAAAAAGGCGGGAATATTCGCTCCCGCCTTTTTAATGCCGTAACAGAAGTTACACGATACCCTGGCTACGCAG
ATAGTCTTCGTAGTTGCCGG

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLPELTDAETLRYNRQIILRGFDFDGQEKLKAARVMIVGLGGLGCAAAPYLAAAGVGHLTLVDFDTVSLSNLQRQILHRD
ARIGMAKVDSARIELSAINPHIHIDAVDRQLDDEQMAAQIAANDLVLDCTDNVATRDLLNRLCHAQRKPLVSGAAIRMEG
QLSVFTYQANEPCYRCLSRLFGDNALTCVEAGVMAPLVGTIGTLQAIEAIKLLTQYGQPLTGKLLMFDAMTMQFREMKLP
KDPQCEVCGGE

Sequences:

>Translated_251_residues
MLPELTDAETLRYNRQIILRGFDFDGQEKLKAARVMIVGLGGLGCAAAPYLAAAGVGHLTLVDFDTVSLSNLQRQILHRD
ARIGMAKVDSARIELSAINPHIHIDAVDRQLDDEQMAAQIAANDLVLDCTDNVATRDLLNRLCHAQRKPLVSGAAIRMEG
QLSVFTYQANEPCYRCLSRLFGDNALTCVEAGVMAPLVGTIGTLQAIEAIKLLTQYGQPLTGKLLMFDAMTMQFREMKLP
KDPQCEVCGGE
>Mature_251_residues
MLPELTDAETLRYNRQIILRGFDFDGQEKLKAARVMIVGLGGLGCAAAPYLAAAGVGHLTLVDFDTVSLSNLQRQILHRD
ARIGMAKVDSARIELSAINPHIHIDAVDRQLDDEQMAAQIAANDLVLDCTDNVATRDLLNRLCHAQRKPLVSGAAIRMEG
QLSVFTYQANEPCYRCLSRLFGDNALTCVEAGVMAPLVGTIGTLQAIEAIKLLTQYGQPLTGKLLMFDAMTMQFREMKLP
KDPQCEVCGGE

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=232, Percent_Identity=42.2413793103448, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI4885649, Length=158, Percent_Identity=31.0126582278481, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI23510338, Length=162, Percent_Identity=30.8641975308642, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI23510340, Length=162, Percent_Identity=30.8641975308642, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=72.1774193548387, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI87082356, Length=247, Percent_Identity=44.9392712550607, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1789177, Length=121, Percent_Identity=32.2314049586777, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17540406, Length=246, Percent_Identity=43.9024390243902, Blast_Score=203, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI193203301, Length=156, Percent_Identity=30.1282051282051, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI86565433, Length=162, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI86565431, Length=162, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=252, Percent_Identity=36.9047619047619, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6322639, Length=171, Percent_Identity=29.8245614035088, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6325438, Length=156, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=251, Percent_Identity=49.003984063745, Blast_Score=230, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24660640, Length=154, Percent_Identity=31.1688311688312, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641311, Length=267, Percent_Identity=28.8389513108614, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573937, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27416; Mature: 27416

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPELTDAETLRYNRQIILRGFDFDGQEKLKAARVMIVGLGGLGCAAAPYLAAAGVGHLT
CCCCCCCHHHHHCCCEEEEEECCCCCHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCEEE
LVDFDTVSLSNLQRQILHRDARIGMAKVDSARIELSAINPHIHIDAVDRQLDDEQMAAQI
EEEECCCCHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCEEEEEECCCCCCHHHHHHHH
AANDLVLDCTDNVATRDLLNRLCHAQRKPLVSGAAIRMEGQLSVFTYQANEPCYRCLSRL
HHCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCHHHHHHHHH
FGDNALTCVEAGVMAPLVGTIGTLQAIEAIKLLTQYGQPLTGKLLMFDAMTMQFREMKLP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCC
KDPQCEVCGGE
CCCCCCCCCCC
>Mature Secondary Structure
MLPELTDAETLRYNRQIILRGFDFDGQEKLKAARVMIVGLGGLGCAAAPYLAAAGVGHLT
CCCCCCCHHHHHCCCEEEEEECCCCCHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCEEE
LVDFDTVSLSNLQRQILHRDARIGMAKVDSARIELSAINPHIHIDAVDRQLDDEQMAAQI
EEEECCCCHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCEEEEEECCCCCCHHHHHHHH
AANDLVLDCTDNVATRDLLNRLCHAQRKPLVSGAAIRMEGQLSVFTYQANEPCYRCLSRL
HHCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCHHHHHHHHH
FGDNALTCVEAGVMAPLVGTIGTLQAIEAIKLLTQYGQPLTGKLLMFDAMTMQFREMKLP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCC
KDPQCEVCGGE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]