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The map label for this gene is ygbJ [H]

Identifier: 157369735

GI number: 157369735

Start: 1626480

End: 1627394

Strand: Reverse

Name: ygbJ [H]

Synonym: Spro_1492

Alternate gene names: 157369735

Gene position: 1627394-1626480 (Counterclockwise)

Preceding gene: 157369737

Following gene: 157369734

Centisome position: 29.87

GC content: 59.02

Gene sequence:

>915_bases
ATGACACAGCCAGCGGATTTTGCAGTTTGCATCGTAGGATTAGGTTCAATGGGCATGGGAGCGGCGAAGTCGTGCATTAA
TGCCGGACTGACTACTTACGGTGTCGATCTTAACCCGCAGGCGCTGGCCTCCTTGCAACAGGCCGGAGCAAAACAGGCGG
CTACCCGCGCAGACGACTTTGCAGCCGAACTCGATGCCTTGTTGCTGCTGGTGGTCAACGCCGCGCAGGTGAAACAGATC
CTGTTTGGTGACAACGGCCTGGCCGCGAAGCTGAAGCCAAATACGCCGGTGATGGTGTCTTCCACCATTTCCGCGGCCGA
TGCCAAACAGATCGAACAGCAGTTACTGGCCCTGGGTCTGAACATGTTGGACGCCCCGGTTTCCGGTGGTGCAGCCAAGG
CTGCCGAGGGCCAGATGACGGTGATGGCCTCCGGTGCCGAATCCACTTTCCGGCAGTTGCAACCGGTGCTGGACGCCATT
GCCGGCAAGGTCTATCGCATTGGCGAAGAGATTGGCCTGGGGGCTACGGTGAAAATCATCCATCAACTGCTGGCCGGGGT
ACATATCGCCGCCGGGGCCGAGGCCATGGCGCTGGCCGCCCGTGCCGGCATCCCGCTGGACGTTATGTACGATGTCGTCA
CCCACGCCGCCGGTAACTCATGGATGTTCGAGAACCGCATGCGCCACGTGGTCGACGGTGACTATGCACCTAAATCGGCG
GTTGATATCTTCGTGAAGGATCTGGGGTTGGTGGCGGATACTGCCAAAGCGCTGCATTTCCCACTGCCGCTGGCCTCAAC
CGCCTTCAATATGTTCACCGCCGCCAGTAATGCCGGTTTCGGTAAAGAGGACGACAGTGCGGTGATCAAGATCTTCGCCG
GTATCGACCTGCCGCAAAAGAAGGAGAACGCATAA

Upstream 100 bases:

>100_bases
CTGTTAATAATTGTGACAACGATCGCTGATGACACACGACAAAGCGCTTATATTTAACATAACAAAACAAATTATCACTA
AAATTAACAGGAGGTGCGCT

Downstream 100 bases:

>100_bases
TGCTGCTCGGCGTCATTGCAGATGATTTTACCGGAGCCACCGATATTGCCAGCTTTCTGGTAGAAAACGGCCTGCCGACG
GTGCAGTTGAACGGCGTGCC

Product: 2-hydroxy-3-oxopropionate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTQPADFAVCIVGLGSMGMGAAKSCINAGLTTYGVDLNPQALASLQQAGAKQAATRADDFAAELDALLLLVVNAAQVKQI
LFGDNGLAAKLKPNTPVMVSSTISAADAKQIEQQLLALGLNMLDAPVSGGAAKAAEGQMTVMASGAESTFRQLQPVLDAI
AGKVYRIGEEIGLGATVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMRHVVDGDYAPKSA
VDIFVKDLGLVADTAKALHFPLPLASTAFNMFTAASNAGFGKEDDSAVIKIFAGIDLPQKKENA

Sequences:

>Translated_304_residues
MTQPADFAVCIVGLGSMGMGAAKSCINAGLTTYGVDLNPQALASLQQAGAKQAATRADDFAAELDALLLLVVNAAQVKQI
LFGDNGLAAKLKPNTPVMVSSTISAADAKQIEQQLLALGLNMLDAPVSGGAAKAAEGQMTVMASGAESTFRQLQPVLDAI
AGKVYRIGEEIGLGATVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMRHVVDGDYAPKSA
VDIFVKDLGLVADTAKALHFPLPLASTAFNMFTAASNAGFGKEDDSAVIKIFAGIDLPQKKENA
>Mature_303_residues
TQPADFAVCIVGLGSMGMGAAKSCINAGLTTYGVDLNPQALASLQQAGAKQAATRADDFAAELDALLLLVVNAAQVKQIL
FGDNGLAAKLKPNTPVMVSSTISAADAKQIEQQLLALGLNMLDAPVSGGAAKAAEGQMTVMASGAESTFRQLQPVLDAIA
GKVYRIGEEIGLGATVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMRHVVDGDYAPKSAV
DIFVKDLGLVADTAKALHFPLPLASTAFNMFTAASNAGFGKEDDSAVIKIFAGIDLPQKKENA

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI23308751, Length=291, Percent_Identity=28.8659793814433, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI40556376, Length=289, Percent_Identity=22.8373702422145, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1789092, Length=302, Percent_Identity=74.5033112582781, Blast_Score=419, Evalue=1e-119,
Organism=Escherichia coli, GI145693186, Length=280, Percent_Identity=33.9285714285714, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790315, Length=284, Percent_Identity=29.9295774647887, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786719, Length=280, Percent_Identity=30.3571428571429, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17557316, Length=270, Percent_Identity=27.037037037037, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655230, Length=289, Percent_Identity=29.0657439446367, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19922568, Length=289, Percent_Identity=29.0657439446367, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28574115, Length=287, Percent_Identity=27.1777003484321, Blast_Score=94, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 31378; Mature: 31246

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00895 3_HYDROXYISOBUT_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPADFAVCIVGLGSMGMGAAKSCINAGLTTYGVDLNPQALASLQQAGAKQAATRADDF
CCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH
AAELDALLLLVVNAAQVKQILFGDNGLAAKLKPNTPVMVSSTISAADAKQIEQQLLALGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHH
NMLDAPVSGGAAKAAEGQMTVMASGAESTFRQLQPVLDAIAGKVYRIGEEIGLGATVKII
HHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMRHVVDGDYAPKSA
HHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHH
VDIFVKDLGLVADTAKALHFPLPLASTAFNMFTAASNAGFGKEDDSAVIKIFAGIDLPQK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCC
KENA
CCCC
>Mature Secondary Structure 
TQPADFAVCIVGLGSMGMGAAKSCINAGLTTYGVDLNPQALASLQQAGAKQAATRADDF
CCCCCCEEEEEECCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH
AAELDALLLLVVNAAQVKQILFGDNGLAAKLKPNTPVMVSSTISAADAKQIEQQLLALGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHH
NMLDAPVSGGAAKAAEGQMTVMASGAESTFRQLQPVLDAIAGKVYRIGEEIGLGATVKII
HHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMRHVVDGDYAPKSA
HHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHH
VDIFVKDLGLVADTAKALHFPLPLASTAFNMFTAASNAGFGKEDDSAVIKIFAGIDLPQK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCC
KENA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]