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The map label for this gene is lrp [C]

Identifier: 157369705

GI number: 157369705

Start: 1594491

End: 1594925

Strand: Reverse

Name: lrp [C]

Synonym: Spro_1462

Alternate gene names: 157369705

Gene position: 1594925-1594491 (Counterclockwise)

Preceding gene: 157369707

Following gene: 157369701

Centisome position: 29.27

GC content: 58.39

Gene sequence:

>435_bases
ATGGATGATATCGATCGCCAAATACTGACCCTGCTGGCGGAGGACGCACGGGTGTCACTGAAAACGCTCAGCGCCAGAGC
CGGGCTGTCTTCACCCAGTACTTCAGAGCGCCTGCGGCGGCTGGAAGAAAATGGTGTGATCCAGGGTTATACCCTGAACG
TCAACTTACAGGCATTGGGCTACGCTTTTCAGTCGCTGGTGCGCATCAAACCGCTGCCGGGCATGCTCAAGAAGGTCGAA
CAGTTGATCCAGGATATCCCGGAGGTGATTGAGTGTGACAAGGTGACCGGCGAGGACTGTTTTATCGTGCGGTTGGTGGC
GCACTCGATGGAGCAACTCGACCAGATCCTCGATCGGCTGGCCGAGCGCGCGCAGAGCAACACTTCCATCGTCAAAACCA
CGCCGGTGAAGCGCCGCCTGCCCCCGCTGCTTTGA

Upstream 100 bases:

>100_bases
GCGACTTTCTCGTGCCGGTTTCTATGGCATAAAAAAGGCCAACATGCTTAACTGCCTTTTTATTTAAGGCATAAATCCAA
ATTAACCTAATGGGGAACTT

Downstream 100 bases:

>100_bases
TTAACGCGTACGTCGGCGGGCGAACGGACTCTTGCGCTTTTTGTCTTTTTTCTCCGCCGCAGCGGCAGATTTAATGGCGG
CCAGGTGTGCCTTGTCGGCC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MDDIDRQILTLLAEDARVSLKTLSARAGLSSPSTSERLRRLEENGVIQGYTLNVNLQALGYAFQSLVRIKPLPGMLKKVE
QLIQDIPEVIECDKVTGEDCFIVRLVAHSMEQLDQILDRLAERAQSNTSIVKTTPVKRRLPPLL

Sequences:

>Translated_144_residues
MDDIDRQILTLLAEDARVSLKTLSARAGLSSPSTSERLRRLEENGVIQGYTLNVNLQALGYAFQSLVRIKPLPGMLKKVE
QLIQDIPEVIECDKVTGEDCFIVRLVAHSMEQLDQILDRLAERAQSNTSIVKTTPVKRRLPPLL
>Mature_144_residues
MDDIDRQILTLLAEDARVSLKTLSARAGLSSPSTSERLRRLEENGVIQGYTLNVNLQALGYAFQSLVRIKPLPGMLKKVE
QLIQDIPEVIECDKVTGEDCFIVRLVAHSMEQLDQILDRLAERAQSNTSIVKTTPVKRRLPPLL

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 16137; Mature: 16137

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDIDRQILTLLAEDARVSLKTLSARAGLSSPSTSERLRRLEENGVIQGYTLNVNLQALG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEEEHHHHH
YAFQSLVRIKPLPGMLKKVEQLIQDIPEVIECDKVTGEDCFIVRLVAHSMEQLDQILDRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AERAQSNTSIVKTTPVKRRLPPLL
HHHHCCCCCEEECCCHHHCCCCCC
>Mature Secondary Structure
MDDIDRQILTLLAEDARVSLKTLSARAGLSSPSTSERLRRLEENGVIQGYTLNVNLQALG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEEEHHHHH
YAFQSLVRIKPLPGMLKKVEQLIQDIPEVIECDKVTGEDCFIVRLVAHSMEQLDQILDRL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AERAQSNTSIVKTTPVKRRLPPLL
HHHHCCCCCEEECCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA