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The map label for this gene is rhtC [H]

Identifier: 157368962

GI number: 157368962

Start: 795078

End: 795692

Strand: Reverse

Name: rhtC [H]

Synonym: Spro_0717

Alternate gene names: 157368962

Gene position: 795692-795078 (Counterclockwise)

Preceding gene: 157368967

Following gene: 157368956

Centisome position: 14.6

GC content: 55.45

Gene sequence:

>615_bases
ATGCTTGAAACTTCGCTGTTCGTTGCCGGTATTGCTACCCTGGGTATGCTGTCGCCCGGCCCGGATTTTTTCATGGTGAT
CAAGAATGCCACCCGCTACCCGCGCCTGGCCGCCATGATGACCGCTTTCGGCGTGATCTGCGGCGTCGCGACCCATATGT
CTTACTGCGTTGCCGGACTGGCGGTAGTGATCACCACCACCCCATGGCTGTTTAACGTACTGAAATACGCCGGTGCGGTC
TATCTGGTCTGGATTGGCATTCAGGCGCTGTTGTCACGCGGCGGCAGTAAAATGAACGTCAGTAATGTGCCACAGCAGCA
GGTGAGTCTGAAAAGTGCCTTTGTGCAGGGCTATCTGTGTAATCTGCTCAATCCGAAGGCCACGTTGTTCTTCCTGGCGG
TATTCACTCAGGTATTGCAGATCGACTCCGGGTTGGGTGAAAAACTGTGGTATGCGGGGATTATCCTTGGCCTGTCCGTC
CTGTGGTGGCCGGTGCTGGTGCTCCTGATCCAAAGTGGTCCGGTGCGTCGCGGGCTGGAAAAGACCCAGAAGATAGTTGA
TAAATTGCTGGGCGGCATGTTGATTGCCCTGGGCATCAAAGTCGCACTGAGCTAA

Upstream 100 bases:

>100_bases
TTCATCATAGTGCTACACATTACCTCATTGGGTTGATGCGTATCAGGGGAAGTGGCGTTATTATCAGCGCAATTAGGCCT
TTTGTGCAGAGAGTCAAATC

Downstream 100 bases:

>100_bases
CTCTTCCAGAATGGGGCGCAGCACCGTGCTGCGCCCATCGGGTTTACCCCTTGGCTTCCACTACCTCATCCTCTGGTGCC
TTGCCGTCAATACTGCCACG

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLETSLFVAGIATLGMLSPGPDFFMVIKNATRYPRLAAMMTAFGVICGVATHMSYCVAGLAVVITTTPWLFNVLKYAGAV
YLVWIGIQALLSRGGSKMNVSNVPQQQVSLKSAFVQGYLCNLLNPKATLFFLAVFTQVLQIDSGLGEKLWYAGIILGLSV
LWWPVLVLLIQSGPVRRGLEKTQKIVDKLLGGMLIALGIKVALS

Sequences:

>Translated_204_residues
MLETSLFVAGIATLGMLSPGPDFFMVIKNATRYPRLAAMMTAFGVICGVATHMSYCVAGLAVVITTTPWLFNVLKYAGAV
YLVWIGIQALLSRGGSKMNVSNVPQQQVSLKSAFVQGYLCNLLNPKATLFFLAVFTQVLQIDSGLGEKLWYAGIILGLSV
LWWPVLVLLIQSGPVRRGLEKTQKIVDKLLGGMLIALGIKVALS
>Mature_204_residues
MLETSLFVAGIATLGMLSPGPDFFMVIKNATRYPRLAAMMTAFGVICGVATHMSYCVAGLAVVITTTPWLFNVLKYAGAV
YLVWIGIQALLSRGGSKMNVSNVPQQQVSLKSAFVQGYLCNLLNPKATLFFLAVFTQVLQIDSGLGEKLWYAGIILGLSV
LWWPVLVLLIQSGPVRRGLEKTQKIVDKLLGGMLIALGIKVALS

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=207, Percent_Identity=32.3671497584541, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788099, Length=194, Percent_Identity=30.9278350515464, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786522, Length=195, Percent_Identity=25.1282051282051, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI48994979, Length=123, Percent_Identity=30.0813008130081, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22010; Mature: 22010

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETSLFVAGIATLGMLSPGPDFFMVIKNATRYPRLAAMMTAFGVICGVATHMSYCVAGL
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVITTTPWLFNVLKYAGAVYLVWIGIQALLSRGGSKMNVSNVPQQQVSLKSAFVQGYLC
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NLLNPKATLFFLAVFTQVLQIDSGLGEKLWYAGIILGLSVLWWPVLVLLIQSGPVRRGLE
HHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KTQKIVDKLLGGMLIALGIKVALS
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLETSLFVAGIATLGMLSPGPDFFMVIKNATRYPRLAAMMTAFGVICGVATHMSYCVAGL
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVITTTPWLFNVLKYAGAVYLVWIGIQALLSRGGSKMNVSNVPQQQVSLKSAFVQGYLC
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NLLNPKATLFFLAVFTQVLQIDSGLGEKLWYAGIILGLSVLWWPVLVLLIQSGPVRRGLE
HHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KTQKIVDKLLGGMLIALGIKVALS
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]