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The map label for this gene is dgoR [H]

Identifier: 157368956

GI number: 157368956

Start: 785718

End: 786449

Strand: Reverse

Name: dgoR [H]

Synonym: Spro_0711

Alternate gene names: 157368956

Gene position: 786449-785718 (Counterclockwise)

Preceding gene: 157368962

Following gene: 157368955

Centisome position: 14.43

GC content: 54.37

Gene sequence:

>732_bases
ATGAAAACCGCACCCACGACCCTATCGGAAACCCTGACGCAAGATTTGGCACGCCGTATTATCAGAGGCGATTTGCCGCC
CGGGCTGTCGTTGCCGGGGGAAAATGAGCTGGCACAGCAGTACGAGGTTTCACGCACCTCGGTACGCAATGCCTTGCAGG
TACTGGCCGCAAAAGGGCTGATTTCCATCCAGGCCAAGAAGCGCAGTACGGTTAACTCACGCCAGCAGTGGAGCTTTTTG
GATACCGATGTTCTGGCCTGGCTGGCAGAAGACAGCCTCGATCCGTTGTTGATTGAACAGCTAATGGTCACTCGTTTGAT
CTTTGAACCCAATATCGCCGCGCTGGCGGCGGTTAATGCCACCGGTCATGATTTAGCGGCGCTCGAAGATGCCTGCAAGT
TGATGGCGCAAGGGCAGCAACAAGCCAGCCGCGAACTGTTCGAACAGGGCGATATGGCATTTCATCTCGCTTTACTGGGG
GCCAGCCATAACCCCTTTTTACATTCATTAGGCAGTGCGCTGTCTGCCGCAATGGCCCTCTCTTTTCAGCAAACGCTGGA
AGAGGACGTACGCCTGGCCCAAAAAGCCGTAGAAGAACACCAACAGCTGCTGGAGGCTATCCGCTTCAAGCAGGTGGAGA
ATGCGCGCCAATGCATGCGTGTCATTCTGCTCAACGCGGCCAGAAAGAATAATTGGCATAAACAGCCGGAAATGTTCGCT
CATATCCTCTAA

Upstream 100 bases:

>100_bases
AAACCCTCATTTCATTCACTAAAACCGGCATGGGTACCACCAATCAGCCGCTTAGCTTAGTATATGGCGTAACTGCCGCT
TTATTGCCTGAGAGCCACGG

Downstream 100 bases:

>100_bases
AAACCCTCCTTTGCTGTAATTTCGATCAATCTCACAGTTCCCGAGTGCTTTTGGCTCTAGCATTCTTGTATTACAAGATT
GATAGTTTTGTATTACCTGA

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKTAPTTLSETLTQDLARRIIRGDLPPGLSLPGENELAQQYEVSRTSVRNALQVLAAKGLISIQAKKRSTVNSRQQWSFL
DTDVLAWLAEDSLDPLLIEQLMVTRLIFEPNIAALAAVNATGHDLAALEDACKLMAQGQQQASRELFEQGDMAFHLALLG
ASHNPFLHSLGSALSAAMALSFQQTLEEDVRLAQKAVEEHQQLLEAIRFKQVENARQCMRVILLNAARKNNWHKQPEMFA
HIL

Sequences:

>Translated_243_residues
MKTAPTTLSETLTQDLARRIIRGDLPPGLSLPGENELAQQYEVSRTSVRNALQVLAAKGLISIQAKKRSTVNSRQQWSFL
DTDVLAWLAEDSLDPLLIEQLMVTRLIFEPNIAALAAVNATGHDLAALEDACKLMAQGQQQASRELFEQGDMAFHLALLG
ASHNPFLHSLGSALSAAMALSFQQTLEEDVRLAQKAVEEHQQLLEAIRFKQVENARQCMRVILLNAARKNNWHKQPEMFA
HIL
>Mature_243_residues
MKTAPTTLSETLTQDLARRIIRGDLPPGLSLPGENELAQQYEVSRTSVRNALQVLAAKGLISIQAKKRSTVNSRQQWSFL
DTDVLAWLAEDSLDPLLIEQLMVTRLIFEPNIAALAAVNATGHDLAALEDACKLMAQGQQQASRELFEQGDMAFHLALLG
ASHNPFLHSLGSALSAAMALSFQQTLEEDVRLAQKAVEEHQQLLEAIRFKQVENARQCMRVILLNAARKNNWHKQPEMFA
HIL

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=214, Percent_Identity=35.5140186915888, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI48994961, Length=204, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790780, Length=207, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786303, Length=220, Percent_Identity=30.4545454545455, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789621, Length=235, Percent_Identity=28.0851063829787, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1789353, Length=170, Percent_Identity=31.7647058823529, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26983; Mature: 26983

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAPTTLSETLTQDLARRIIRGDLPPGLSLPGENELAQQYEVSRTSVRNALQVLAAKGL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISIQAKKRSTVNSRQQWSFLDTDVLAWLAEDSLDPLLIEQLMVTRLIFEPNIAALAAVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHEECC
TGHDLAALEDACKLMAQGQQQASRELFEQGDMAFHLALLGASHNPFLHSLGSALSAAMAL
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SFQQTLEEDVRLAQKAVEEHQQLLEAIRFKQVENARQCMRVILLNAARKNNWHKQPEMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
HIL
HCC
>Mature Secondary Structure
MKTAPTTLSETLTQDLARRIIRGDLPPGLSLPGENELAQQYEVSRTSVRNALQVLAAKGL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISIQAKKRSTVNSRQQWSFLDTDVLAWLAEDSLDPLLIEQLMVTRLIFEPNIAALAAVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHEECC
TGHDLAALEDACKLMAQGQQQASRELFEQGDMAFHLALLGASHNPFLHSLGSALSAAMAL
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SFQQTLEEDVRLAQKAVEEHQQLLEAIRFKQVENARQCMRVILLNAARKNNWHKQPEMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
HIL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]