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The map label for this gene is rsmC

Identifier: 157368894

GI number: 157368894

Start: 714386

End: 715429

Strand: Reverse

Name: rsmC

Synonym: Spro_0649

Alternate gene names: 157368894

Gene position: 715429-714386 (Counterclockwise)

Preceding gene: 157368910

Following gene: 157368892

Centisome position: 13.13

GC content: 58.43

Gene sequence:

>1044_bases
ATGTCTGCATTAACCCCCGCCAGTGAAGTCATGCTGCGCCACAGTGATGAGTTTATCGAACGCCGCGTTCTGTTCGCCGG
TGACCTGCAGGACGCCCTGCCGGCCCAATTTGAGGCCGCGGATGTGCGTGTCCATACCCAGCAATACCATCACTGGCAGT
TACTGAACCGGGCGATGGGTGACAACGTGCAGTACGGCCTGACCGTAGACGCTGCGTTCGTCGCCGAGTGCGATACGCTG
ATCTACTACTGGCCGAAGAGCAAACAGGAAGCGCAATTCCAGCTGTGCAACATTCTGGCACTGCTGCCGGTAGGCACTGA
CGTGTTCGTAGTCGGTGAGAACCGCAGCGGCGTGCGCAGCGCCGATCAGATGGTGGAAGATTACGCCACACTGGTGAAAA
TCGACAGCGCCCGCCGCTGTGGCCTGTATCACGGTCGCCTGGACACCCAGACCGAATTCAACCTGGAAGACTGGTGGGAA
AGCTATCAGTTGCACGATCTGGAAGTGAAAACCCTGCCGGGCGTGTTCAGCCGCGACGGACTGGATGTCGGTAGCTCACT
GCTGCTGTCGACGCTGGATAAACACATGAAAGGCAAAGTGCTGGACGTGGGTTGTGGTGCCGGTGTGATGGCCTCGGTGC
TGTCCAAACTGTCGCCAAAAATGAAGCTGACCCTCAGCGATGTCAACGCCGCAGCCATTGAGTCCAGCCGCGCAACGCTG
GCCGCTAACGGCATTGAAGGTGAAGTGATTGTCAGTAACGTCTATTCCGACATTACCGGCCGTTTCGATCTGATCATCTC
CAACCCACCGTTCCATGATGGGCTGCAAACCAGCCTGACGGCGGCGGAAACCCTGATCCGCGGTGCGTTGAAGCACTTAG
GCGTCGGCGGTAAACTGCGCATCGTGGCCAACGCCTTCCTGCCGTACCCGGACATTCTGGACGCCACCTTCGGCAGCCAT
GAAGTGCTGGCGCAAAACGGCCGCTTCAAGGTGTACCAGGCAACCGTTGCCCGTGCACCACGCGATGCCAAGAAGAAGAA
ATAA

Upstream 100 bases:

>100_bases
CTATGCTAACAAACCCGCGCGGCCTGCGCCAACAAACCCGTCGAACATATCGCCACAAAGCTCTATAATCCCCGGTCTAA
TTTCTAGGAGCCAAAACCTG

Downstream 100 bases:

>100_bases
GTAACGCCGCCCGCAAATAGCGGGGATCAGGGCGCAGCGTTCACACGCCGCGCCCTTTTTTTATCCGTTGATATAGGTCA
TCGACTCTGCGCCATAGCGT

Product: 16S ribosomal RNA m2G1207 methyltransferase

Products: NA

Alternate protein names: 16S rRNA m2G1207 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rsmC

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSALTPASEVMLRHSDEFIERRVLFAGDLQDALPAQFEAADVRVHTQQYHHWQLLNRAMGDNVQYGLTVDAAFVAECDTL
IYYWPKSKQEAQFQLCNILALLPVGTDVFVVGENRSGVRSADQMVEDYATLVKIDSARRCGLYHGRLDTQTEFNLEDWWE
SYQLHDLEVKTLPGVFSRDGLDVGSSLLLSTLDKHMKGKVLDVGCGAGVMASVLSKLSPKMKLTLSDVNAAAIESSRATL
AANGIEGEVIVSNVYSDITGRFDLIISNPPFHDGLQTSLTAAETLIRGALKHLGVGGKLRIVANAFLPYPDILDATFGSH
EVLAQNGRFKVYQATVARAPRDAKKKK

Sequences:

>Translated_347_residues
MSALTPASEVMLRHSDEFIERRVLFAGDLQDALPAQFEAADVRVHTQQYHHWQLLNRAMGDNVQYGLTVDAAFVAECDTL
IYYWPKSKQEAQFQLCNILALLPVGTDVFVVGENRSGVRSADQMVEDYATLVKIDSARRCGLYHGRLDTQTEFNLEDWWE
SYQLHDLEVKTLPGVFSRDGLDVGSSLLLSTLDKHMKGKVLDVGCGAGVMASVLSKLSPKMKLTLSDVNAAAIESSRATL
AANGIEGEVIVSNVYSDITGRFDLIISNPPFHDGLQTSLTAAETLIRGALKHLGVGGKLRIVANAFLPYPDILDATFGSH
EVLAQNGRFKVYQATVARAPRDAKKKK
>Mature_346_residues
SALTPASEVMLRHSDEFIERRVLFAGDLQDALPAQFEAADVRVHTQQYHHWQLLNRAMGDNVQYGLTVDAAFVAECDTLI
YYWPKSKQEAQFQLCNILALLPVGTDVFVVGENRSGVRSADQMVEDYATLVKIDSARRCGLYHGRLDTQTEFNLEDWWES
YQLHDLEVKTLPGVFSRDGLDVGSSLLLSTLDKHMKGKVLDVGCGAGVMASVLSKLSPKMKLTLSDVNAAAIESSRATLA
ANGIEGEVIVSNVYSDITGRFDLIISNPPFHDGLQTSLTAAETLIRGALKHLGVGGKLRIVANAFLPYPDILDATFGSHE
VLAQNGRFKVYQATVARAPRDAKKKK

Specific function: Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmC family

Homologues:

Organism=Escherichia coli, GI1790830, Length=338, Percent_Identity=70.1183431952663, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI87082206, Length=174, Percent_Identity=32.183908045977, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMC_SERP5 (A8G9G5)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476883.1
- ProteinModelPortal:   A8G9G5
- SMR:   A8G9G5
- STRING:   A8G9G5
- GeneID:   5605798
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0649
- eggNOG:   COG2813
- HOGENOM:   HBG296757
- OMA:   TGKFKVY
- ProtClustDB:   PRK09489
- BioCyc:   SPRO399741:SPRO_0649-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01862
- InterPro:   IPR002052
- InterPro:   IPR013675
- InterPro:   IPR007848

Pfam domain/function: PF05175 MTS; PF08468 MTS_N

EC number: =2.1.1.172

Molecular weight: Translated: 38140; Mature: 38009

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALTPASEVMLRHSDEFIERRVLFAGDLQDALPAQFEAADVRVHTQQYHHWQLLNRAMG
CCCCCCHHHHHHHCCHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHC
DNVQYGLTVDAAFVAECDTLIYYWPKSKQEAQFQLCNILALLPVGTDVFVVGENRSGVRS
CCCEEEEEECHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCHH
ADQMVEDYATLVKIDSARRCGLYHGRLDTQTEFNLEDWWESYQLHDLEVKTLPGVFSRDG
HHHHHHHHHHHHEECCCCCCCEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCC
LDVGSSLLLSTLDKHMKGKVLDVGCGAGVMASVLSKLSPKMKLTLSDVNAAAIESSRATL
CCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCEE
AANGIEGEVIVSNVYSDITGRFDLIISNPPFHDGLQTSLTAAETLIRGALKHLGVGGKLR
EECCCCCEEEEEHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IVANAFLPYPDILDATFGSHEVLAQNGRFKVYQATVARAPRDAKKKK
EEEECCCCCCHHHHCCCCCCHHHHCCCCEEEEEEHHHCCCCHHCCCC
>Mature Secondary Structure 
SALTPASEVMLRHSDEFIERRVLFAGDLQDALPAQFEAADVRVHTQQYHHWQLLNRAMG
CCCCCHHHHHHHCCHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHC
DNVQYGLTVDAAFVAECDTLIYYWPKSKQEAQFQLCNILALLPVGTDVFVVGENRSGVRS
CCCEEEEEECHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEECCCEEEEEECCCCCCHH
ADQMVEDYATLVKIDSARRCGLYHGRLDTQTEFNLEDWWESYQLHDLEVKTLPGVFSRDG
HHHHHHHHHHHHEECCCCCCCEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCCCC
LDVGSSLLLSTLDKHMKGKVLDVGCGAGVMASVLSKLSPKMKLTLSDVNAAAIESSRATL
CCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCEE
AANGIEGEVIVSNVYSDITGRFDLIISNPPFHDGLQTSLTAAETLIRGALKHLGVGGKLR
EECCCCCEEEEEHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
IVANAFLPYPDILDATFGSHEVLAQNGRFKVYQATVARAPRDAKKKK
EEEECCCCCCHHHHCCCCCCHHHHCCCCEEEEEEHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA