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The map label for this gene is ybhD [H]

Identifier: 157368834

GI number: 157368834

Start: 653756

End: 654649

Strand: Reverse

Name: ybhD [H]

Synonym: Spro_0589

Alternate gene names: 157368834

Gene position: 654649-653756 (Counterclockwise)

Preceding gene: 157368841

Following gene: 157368833

Centisome position: 12.01

GC content: 60.85

Gene sequence:

>894_bases
ATGAGCATCAAACAGTTACGCGCGTTTTTAGCGGTAGCTCACACTCTTAACTTCGCCCAGGCGAGCGAACGGCTGAATAT
TTCGCAGCCGGCGCTGAGTCTCGCCATTCGCGGACTGGAAGAGGTGTTGGGGGGACAGTTGCTGCTGCGTACCACCCGAC
GTGTGGCGCTGACGCCGGAAGGGGAAAGCTTCTTCCCGATGGCGCGCCAACTGTTGGCGGACTGGGACAATGCGGAAGAG
GCGATGCGTCAGCGTTTTACCCTGCAACTGGGCAAAGTGGCGATCGCTGCCATGCCTTCGTTCGCTGCCAACCCGCTGCC
GCCGATCCTGAAAGTGTTTCGCGATCACTACGCCGGGATCAACGTGGCGGTGCACGACGTGATTAACGAGCAGGTGTTCG
AGATGATCCGCGAAGGCCGGGTGGAAATGGGCATTGCCTTCGAGCCGGAGCCCAGCGATACCCTGCACTTCACCCCGTTG
TGCAACGATCGCTTTGTGGCGGTGGTGCCAAAGCATTCACCGCTGGCGAGCCGGGCGCAGGTGAGCTGGAAAGAGTTGTT
GACGCTGGACTTTATTACCCTGCAGCGCCCTTCTGCGGTGCGTCTGTTGCTGGAACAAACGCTGGCCAAAAGCGGCAGAA
CGCTGGAGGTGGCGTTTGAAAGCCACCAGTTGGTGACGGTCGGCCGCATGGTGGCTAACGGACTGGGCGCCAGCGCGGTA
CCGGCGCTGTGTGAACAACAGATGGGCGAGTTAGGTGCAACCTGCGTGCCGTTATTCGGCCCGGTGATTGAACGCCGGGT
CGGACTGATCCGCCTCGCCCAGCACCGTCTGTCTTCGGCGGCTCAGGCGCTGGCCGGGGTGATTGAACGGGAAATGGCGA
TGAGTGGAGTTTAA

Upstream 100 bases:

>100_bases
TGATTTGTTAATTTTGTTTTTGTGCCCCATTGATTTAAAATTTTTATTAATAAATTGTTAATTACTGTTTTCAAAAGAGT
TAAATAATTCAAAAATGAAA

Downstream 100 bases:

>100_bases
TATAGAGTAATTATTTATCCTTATTAAAATTCGATAAATATAAAAGGATTGTAAAATGCAAGAAAAAAACAACTCAGATA
TCATGCATAAAATCAAAAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSIKQLRAFLAVAHTLNFAQASERLNISQPALSLAIRGLEEVLGGQLLLRTTRRVALTPEGESFFPMARQLLADWDNAEE
AMRQRFTLQLGKVAIAAMPSFAANPLPPILKVFRDHYAGINVAVHDVINEQVFEMIREGRVEMGIAFEPEPSDTLHFTPL
CNDRFVAVVPKHSPLASRAQVSWKELLTLDFITLQRPSAVRLLLEQTLAKSGRTLEVAFESHQLVTVGRMVANGLGASAV
PALCEQQMGELGATCVPLFGPVIERRVGLIRLAQHRLSSAAQALAGVIEREMAMSGV

Sequences:

>Translated_297_residues
MSIKQLRAFLAVAHTLNFAQASERLNISQPALSLAIRGLEEVLGGQLLLRTTRRVALTPEGESFFPMARQLLADWDNAEE
AMRQRFTLQLGKVAIAAMPSFAANPLPPILKVFRDHYAGINVAVHDVINEQVFEMIREGRVEMGIAFEPEPSDTLHFTPL
CNDRFVAVVPKHSPLASRAQVSWKELLTLDFITLQRPSAVRLLLEQTLAKSGRTLEVAFESHQLVTVGRMVANGLGASAV
PALCEQQMGELGATCVPLFGPVIERRVGLIRLAQHRLSSAAQALAGVIEREMAMSGV
>Mature_296_residues
SIKQLRAFLAVAHTLNFAQASERLNISQPALSLAIRGLEEVLGGQLLLRTTRRVALTPEGESFFPMARQLLADWDNAEEA
MRQRFTLQLGKVAIAAMPSFAANPLPPILKVFRDHYAGINVAVHDVINEQVFEMIREGRVEMGIAFEPEPSDTLHFTPLC
NDRFVAVVPKHSPLASRAQVSWKELLTLDFITLQRPSAVRLLLEQTLAKSGRTLEVAFESHQLVTVGRMVANGLGASAVP
ALCEQQMGELGATCVPLFGPVIERRVGLIRLAQHRLSSAAQALAGVIEREMAMSGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=280, Percent_Identity=33.2142857142857, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788748, Length=293, Percent_Identity=32.7645051194539, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI157672245, Length=284, Percent_Identity=29.5774647887324, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=30.6122448979592, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787879, Length=259, Percent_Identity=30.1158301158301, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=25.5972696245734, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787601, Length=268, Percent_Identity=28.7313432835821, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367136, Length=258, Percent_Identity=27.1317829457364, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788297, Length=263, Percent_Identity=25.0950570342205, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788481, Length=283, Percent_Identity=27.5618374558304, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789204, Length=300, Percent_Identity=26.3333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789173, Length=276, Percent_Identity=26.4492753623188, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081904, Length=175, Percent_Identity=28, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786401, Length=170, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693193, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=143, Percent_Identity=31.4685314685315, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790208, Length=194, Percent_Identity=27.319587628866, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32534; Mature: 32403

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKQLRAFLAVAHTLNFAQASERLNISQPALSLAIRGLEEVLGGQLLLRTTRRVALTPE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHEEHHCCEEEECCC
GESFFPMARQLLADWDNAEEAMRQRFTLQLGKVAIAAMPSFAANPLPPILKVFRDHYAGI
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
NVAVHDVINEQVFEMIREGRVEMGIAFEPEPSDTLHFTPLCNDRFVAVVPKHSPLASRAQ
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCCEEEEECCCCCCHHHHH
VSWKELLTLDFITLQRPSAVRLLLEQTLAKSGRTLEVAFESHQLVTVGRMVANGLGASAV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCHHH
PALCEQQMGELGATCVPLFGPVIERRVGLIRLAQHRLSSAAQALAGVIEREMAMSGV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIKQLRAFLAVAHTLNFAQASERLNISQPALSLAIRGLEEVLGGQLLLRTTRRVALTPE
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHEEHHCCEEEECCC
GESFFPMARQLLADWDNAEEAMRQRFTLQLGKVAIAAMPSFAANPLPPILKVFRDHYAGI
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCC
NVAVHDVINEQVFEMIREGRVEMGIAFEPEPSDTLHFTPLCNDRFVAVVPKHSPLASRAQ
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCCEEEEECCCCCCHHHHH
VSWKELLTLDFITLQRPSAVRLLLEQTLAKSGRTLEVAFESHQLVTVGRMVANGLGASAV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCHHH
PALCEQQMGELGATCVPLFGPVIERRVGLIRLAQHRLSSAAQALAGVIEREMAMSGV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]