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The map label for this gene is nrdD [H]

Identifier: 157368772

GI number: 157368772

Start: 576256

End: 578394

Strand: Reverse

Name: nrdD [H]

Synonym: Spro_0525

Alternate gene names: 157368772

Gene position: 578394-576256 (Counterclockwise)

Preceding gene: 157368773

Following gene: 157368771

Centisome position: 10.61

GC content: 58.35

Gene sequence:

>2139_bases
GTGAAACCAGTAGTGATTAAACGGGACGGTTGTCAGGTACCTTTTGACGAGGCACGTATTGGGCAGGCTATCGAGCGCGC
CGCGCTGGCCGTCGGTATTGTCAATGCCGACTACTGCGCTACCGTCGCCCGCGTAGTCGCTCAACGGATGTCACAGCAGC
AGCGCGTTGATATCCATGAAATTCAGCAGGCGGTAGAAAATCAGTTGATGGCCGGCGAATACAAGCAACTGGCCCGCGCC
TATATTGAATATCGCCACGATCGCGACGTAGCGCGTGAACTGCGCGGGCGGCTGAACCAGGAGATCCGTGGCCTGGTGGA
GCAAAGCAACATGGCGCTGCTAAACGAAAACGCCAACAAGGACAGCAAAGTGATCCCCACCCAGCGCGATCTGCTGGCCG
GGATCGTCGCCAAGCATTATGCCAAGCAACACATCCTGCCGCGTGACGTAGTGCTGGCCCACGAGCGCGGCGAGATCCAC
TACCACGATCTCGATTACTCGCCGTTCTTCCCGATGTTCAACTGCATGTTGATCGACCTGAAAGGCATGCTGACCAACGG
CTTCAAGATGGGCAACGCCGAGATCGAACCGCCGAAGTCGATCTCCACCGCCACTGCAGTCACCGCCCAGATCATCGCGC
AGGTTGCCAGCCATATTTATGGCGGCACCACCATTAACCGCATCGACGAGATCCTGGCCCCGTTCGTCAGCGAAAGCTTC
AACAAGCATCGGCAGGTCGCCGAACAGTGGCAGATCCCGGACGCACAAGGCTACGCCATGGCACGCACCGAGAAAGAGTG
TTACGACGCCTTCCAGTCGCTGGAATATGAGGTCAACACCCTGCACACCGCCAACGGCCAGACGCCGTTCGTGACCTTCG
GTTTTGGCCTGGGCACCTGCTGGGAATCACGGATGATCCAGCGTTCAATCCTGCAAAATCGCATCGCCGGGCTGGGCAAG
AACCGTAAGACGGCGGTGTTCCCCAAACTGGTGTTCGCCATCCGCGACGGCCTTAATCACCAGTACGGCGATCCGAACTA
CGATATCAAACAGCTGGCGCTGGAGTGCGCCAGCAAGCGCATGTACCCGGACATCCTCAATTACGATCAGGTGGTGAAAG
TCACCGGCTCGTTCAAAACCCCGATGGGGTGCCGCAGCTTCCTCGGTACCTATGAAGAAAATGGCGAACTGGTGCACGAC
GGCCGCAACAATATCGGCGTGATCAGCCTGAATCTACCGCGCATTGCGCTGGAGGCGGTCGGCGATGAAAACCGCTTCTG
GCAACTGCTTGACCAGCGTTTGCTGTTGGCGAAAAAGGCGCTGATGACGCGCATTGCCCGGCTGGAAGGCATCAAGGCCC
GGGTCGCGCCAATTTTGTATATGGAAGGCGCCTGCGGTGTACGCCTGAAGGCGGACGACAATATCGCCGACATTTTCAAG
AATGGCCGTGCGTCGATCTCACTGGGTTATATCGGCCTGCATGAGACCATCAACGCGCTGTTCGGTGACCAACGGCACGT
CTACGACGACGAAGCGCTGCGCGCCAAGGCGGTTGCCATTGTTGCCCGCCTGCGGGCCGCCACCGACAGTTGGAAGGAAG
AAACCGGTTATGGCTTCAGCCTGTACAGCACGCCGAGCGAGAACCTGTGCGACCGCTTCTGCCGGTTGGATACCGCCGAT
TTCGGCGTGGTACCGGGCGTCACCGACAAAGGCTATTACACCAACAGCTTCCACCTCGACGTGGAGAAAAAGGTCAATCC
TTACGACAAACTGGATTTTGAAGCGCCTTATCCCCCGTTGGCCAACGGCGGTTTCATCTGTTATGGCGAATACCCGAACC
TGCAGCACAACCTGAAAGCGCTGGAAGACGTGTGGGATTACAGCTACAGCCGCGTACCTTATTACGGCACCAATACGCCG
ATCGATGAGTGCTACGAGTGCGGCTTCACCGGCGAGTTTGCCTGTACCAGCAAGGGCTTCACCTGCCCGAAATGCGGCAA
CCACGAGCCGTCCAAGGTGTCCGTCACCCGTCGGGTGTGTGGTTACCTCGGCAGCCCGGACGCCAGGCCGTTCAACGCCG
GTAAGCAGGAAGAAGTGAAACGCCGGGTGAAACACCTGGGGAATGGGCAAATCGGCTAA

Upstream 100 bases:

>100_bases
CTGCGGCATTGCCCTGTGGATAAGCCGAAATCATACCGATACCCAACGGCTTTTAGCCTGCCGGGCATCAGCGCTCCCTC
GGGGAACAAGGAGTAACAAC

Downstream 100 bases:

>100_bases
CGCCGGGCCGCTCTGCATCAGGGCTCAGCATGCTGAGCCCCTACCATCAGAAAGCGAAATATGAACTACCACCAGTATTA
TCCCATCGACGTGGTCAACG

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MKPVVIKRDGCQVPFDEARIGQAIERAALAVGIVNADYCATVARVVAQRMSQQQRVDIHEIQQAVENQLMAGEYKQLARA
YIEYRHDRDVARELRGRLNQEIRGLVEQSNMALLNENANKDSKVIPTQRDLLAGIVAKHYAKQHILPRDVVLAHERGEIH
YHDLDYSPFFPMFNCMLIDLKGMLTNGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEILAPFVSESF
NKHRQVAEQWQIPDAQGYAMARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTCWESRMIQRSILQNRIAGLGK
NRKTAVFPKLVFAIRDGLNHQYGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGTYEENGELVHD
GRNNIGVISLNLPRIALEAVGDENRFWQLLDQRLLLAKKALMTRIARLEGIKARVAPILYMEGACGVRLKADDNIADIFK
NGRASISLGYIGLHETINALFGDQRHVYDDEALRAKAVAIVARLRAATDSWKEETGYGFSLYSTPSENLCDRFCRLDTAD
FGVVPGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPLANGGFICYGEYPNLQHNLKALEDVWDYSYSRVPYYGTNTP
IDECYECGFTGEFACTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG

Sequences:

>Translated_712_residues
MKPVVIKRDGCQVPFDEARIGQAIERAALAVGIVNADYCATVARVVAQRMSQQQRVDIHEIQQAVENQLMAGEYKQLARA
YIEYRHDRDVARELRGRLNQEIRGLVEQSNMALLNENANKDSKVIPTQRDLLAGIVAKHYAKQHILPRDVVLAHERGEIH
YHDLDYSPFFPMFNCMLIDLKGMLTNGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEILAPFVSESF
NKHRQVAEQWQIPDAQGYAMARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTCWESRMIQRSILQNRIAGLGK
NRKTAVFPKLVFAIRDGLNHQYGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGTYEENGELVHD
GRNNIGVISLNLPRIALEAVGDENRFWQLLDQRLLLAKKALMTRIARLEGIKARVAPILYMEGACGVRLKADDNIADIFK
NGRASISLGYIGLHETINALFGDQRHVYDDEALRAKAVAIVARLRAATDSWKEETGYGFSLYSTPSENLCDRFCRLDTAD
FGVVPGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPLANGGFICYGEYPNLQHNLKALEDVWDYSYSRVPYYGTNTP
IDECYECGFTGEFACTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
>Mature_712_residues
MKPVVIKRDGCQVPFDEARIGQAIERAALAVGIVNADYCATVARVVAQRMSQQQRVDIHEIQQAVENQLMAGEYKQLARA
YIEYRHDRDVARELRGRLNQEIRGLVEQSNMALLNENANKDSKVIPTQRDLLAGIVAKHYAKQHILPRDVVLAHERGEIH
YHDLDYSPFFPMFNCMLIDLKGMLTNGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEILAPFVSESF
NKHRQVAEQWQIPDAQGYAMARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTCWESRMIQRSILQNRIAGLGK
NRKTAVFPKLVFAIRDGLNHQYGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGTYEENGELVHD
GRNNIGVISLNLPRIALEAVGDENRFWQLLDQRLLLAKKALMTRIARLEGIKARVAPILYMEGACGVRLKADDNIADIFK
NGRASISLGYIGLHETINALFGDQRHVYDDEALRAKAVAIVARLRAATDSWKEETGYGFSLYSTPSENLCDRFCRLDTAD
FGVVPGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPLANGGFICYGEYPNLQHNLKALEDVWDYSYSRVPYYGTNTP
IDECYECGFTGEFACTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=713, Percent_Identity=86.2552594670407, Blast_Score=1305, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 79913; Mature: 79913

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVVIKRDGCQVPFDEARIGQAIERAALAVGIVNADYCATVARVVAQRMSQQQRVDIHE
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
IQQAVENQLMAGEYKQLARAYIEYRHDRDVARELRGRLNQEIRGLVEQSNMALLNENANK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
DSKVIPTQRDLLAGIVAKHYAKQHILPRDVVLAHERGEIHYHDLDYSPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEECCCCCCCHHHHHHHHHHH
KGMLTNGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEILAPFVSESF
HHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NKHRQVAEQWQIPDAQGYAMARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTC
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEECCCCCCEEEECCCHHHH
WESRMIQRSILQNRIAGLGKNRKTAVFPKLVFAIRDGLNHQYGDPNYDIKQLALECASKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
MYPDILNYDQVVKVTGSFKTPMGCRSFLGTYEENGELVHDGRNNIGVISLNLPRIALEAV
CCHHHCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCEEHHHC
GDENRFWQLLDQRLLLAKKALMTRIARLEGIKARVAPILYMEGACGVRLKADDNIADIFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHHC
NGRASISLGYIGLHETINALFGDQRHVYDDEALRAKAVAIVARLRAATDSWKEETGYGFS
CCCCEEEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LYSTPSENLCDRFCRLDTADFGVVPGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPL
EECCCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNLQHNLKALEDVWDYSYSRVPYYGTNTPIDECYECGFTGEFACTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCC
TCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPVVIKRDGCQVPFDEARIGQAIERAALAVGIVNADYCATVARVVAQRMSQQQRVDIHE
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
IQQAVENQLMAGEYKQLARAYIEYRHDRDVARELRGRLNQEIRGLVEQSNMALLNENANK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
DSKVIPTQRDLLAGIVAKHYAKQHILPRDVVLAHERGEIHYHDLDYSPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCEEEECCCCCCCHHHHHHHHHHH
KGMLTNGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEILAPFVSESF
HHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NKHRQVAEQWQIPDAQGYAMARTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTC
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEECCCCCCEEEECCCHHHH
WESRMIQRSILQNRIAGLGKNRKTAVFPKLVFAIRDGLNHQYGDPNYDIKQLALECASKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
MYPDILNYDQVVKVTGSFKTPMGCRSFLGTYEENGELVHDGRNNIGVISLNLPRIALEAV
CCHHHCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCEEHHHC
GDENRFWQLLDQRLLLAKKALMTRIARLEGIKARVAPILYMEGACGVRLKADDNIADIFK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHHC
NGRASISLGYIGLHETINALFGDQRHVYDDEALRAKAVAIVARLRAATDSWKEETGYGFS
CCCCEEEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LYSTPSENLCDRFCRLDTADFGVVPGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPL
EECCCCHHHHHHHHCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNLQHNLKALEDVWDYSYSRVPYYGTNTPIDECYECGFTGEFACTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCC
TCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]