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The map label for this gene is murB [H]

Identifier: 157368516

GI number: 157368516

Start: 304136

End: 305173

Strand: Direct

Name: murB [H]

Synonym: Spro_0267

Alternate gene names: 157368516

Gene position: 304136-305173 (Clockwise)

Preceding gene: 157368515

Following gene: 157368517

Centisome position: 5.58

GC content: 49.33

Gene sequence:

>1038_bases
ATGTCTACTGAAAGCGCGTCATTAAAAAAACACAATACTTTTGCGCTCCCGGTCAACGCAGCGCATCTGGTCATTGCAGA
AACAATCGAATTAATGATCAAGGTTTGGCAGAAAACACAGAAGCGTCAAGAGCCGCTACTGGTACTTGGAGAAGGGAGTA
ACGTCCTGTTTCTTGATGATTTTTCCGGTACGGTAATGATCAATCAATTAAAAGGTATCGACATCCGAGAAGAGAAAGAT
GCCTGGTTTCTTCACGTTAGCTCTGGTGAGAATTGGCATGGTTTGGTTTGTCGCACTCTGGAAATCGGCATTCCCGGGCT
GGAAAACCTGGCGTTAATCCCCGGCCTGGTCGGCTCTGCACCTATTCAGAACATCGGTGCCTATGGTATCGAACTCAAGA
GCGTATGTGACTACGTTGATCTATTGGATCTGACTACGGGTGCCATCGATCGCATTGCCGCATCTGACTGTGGCTTTGGT
TACCGAGAAAGTATTTTTAAACATCATTTTCAGAAGGGGCATATCATTGTTGGTGTGGGCCTGCGTCTTAGCAAGCAATG
GGATCCGATGCTGAATTATGGCGATCTGACAAAGCTGGACCCTGAAACGGTGACACCACGTCAGGTATTTGACTCTGTAT
GTGCAATGCGCCGCAGCAAATTGCCCGACCCTAAAGTGACGGGTAATGCAGGCAGCTTCTTCAAAAACCCACTGGTTGGT
AGTGAAAAAGCCGCTGAGTTGACCACCGAATATCCTGGCATACCGCATTATCCGCAGCAGGATGGTCAGGTGAAGCTGGC
TGCAGGCTGGTTGATCGATCAGTGTGGGCTGAAAGGACACCAAATTGGCGGTGCGGCGGTACATAATCAACAGGCGCTTG
TGCTGGTTAATGCGGATAATGCCGCCAGTCAGGACGTGGTGGCGCTGGCACGGCATGTACGTAATACCGTAGCGAAAAAA
TTCGACGTATGGCTTGAGCCGGAAGTTCGCTTTATCGGTGCGGTTGGTGAGTTGAATGCCGTAGAGGTTCTTTCATGA

Upstream 100 bases:

>100_bases
TCTCCAGATAAAAACCCTATCGATGAAAACAAATATTAGCCTGGCGTGCCGAATCGAGTAGACTAGGTGCAGGTTCATTT
CCGTATAGGTATTTATCGTT

Downstream 100 bases:

>100_bases
AGGACACCAAAGTTCCCCTTAAGCTCATTTCTATACTGGCTGATGGCGATTTCCATTCTGGTGAGCATCTTGGCGAGTTG
CTGGGCATGAGTCGTGCCGC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSTESASLKKHNTFALPVNAAHLVIAETIELMIKVWQKTQKRQEPLLVLGEGSNVLFLDDFSGTVMINQLKGIDIREEKD
AWFLHVSSGENWHGLVCRTLEIGIPGLENLALIPGLVGSAPIQNIGAYGIELKSVCDYVDLLDLTTGAIDRIAASDCGFG
YRESIFKHHFQKGHIIVGVGLRLSKQWDPMLNYGDLTKLDPETVTPRQVFDSVCAMRRSKLPDPKVTGNAGSFFKNPLVG
SEKAAELTTEYPGIPHYPQQDGQVKLAAGWLIDQCGLKGHQIGGAAVHNQQALVLVNADNAASQDVVALARHVRNTVAKK
FDVWLEPEVRFIGAVGELNAVEVLS

Sequences:

>Translated_345_residues
MSTESASLKKHNTFALPVNAAHLVIAETIELMIKVWQKTQKRQEPLLVLGEGSNVLFLDDFSGTVMINQLKGIDIREEKD
AWFLHVSSGENWHGLVCRTLEIGIPGLENLALIPGLVGSAPIQNIGAYGIELKSVCDYVDLLDLTTGAIDRIAASDCGFG
YRESIFKHHFQKGHIIVGVGLRLSKQWDPMLNYGDLTKLDPETVTPRQVFDSVCAMRRSKLPDPKVTGNAGSFFKNPLVG
SEKAAELTTEYPGIPHYPQQDGQVKLAAGWLIDQCGLKGHQIGGAAVHNQQALVLVNADNAASQDVVALARHVRNTVAKK
FDVWLEPEVRFIGAVGELNAVEVLS
>Mature_344_residues
STESASLKKHNTFALPVNAAHLVIAETIELMIKVWQKTQKRQEPLLVLGEGSNVLFLDDFSGTVMINQLKGIDIREEKDA
WFLHVSSGENWHGLVCRTLEIGIPGLENLALIPGLVGSAPIQNIGAYGIELKSVCDYVDLLDLTTGAIDRIAASDCGFGY
RESIFKHHFQKGHIIVGVGLRLSKQWDPMLNYGDLTKLDPETVTPRQVFDSVCAMRRSKLPDPKVTGNAGSFFKNPLVGS
EKAAELTTEYPGIPHYPQQDGQVKLAAGWLIDQCGLKGHQIGGAAVHNQQALVLVNADNAASQDVVALARHVRNTVAKKF
DVWLEPEVRFIGAVGELNAVEVLS

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=339, Percent_Identity=64.8967551622419, Blast_Score=467, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37650; Mature: 37518

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTESASLKKHNTFALPVNAAHLVIAETIELMIKVWQKTQKRQEPLLVLGEGSNVLFLDD
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEC
FSGTVMINQLKGIDIREEKDAWFLHVSSGENWHGLVCRTLEIGIPGLENLALIPGLVGSA
CCCEEEEEEECCCCEEECCCEEEEEECCCCCCCEEEEEEEEECCCCCCCHHHHCCCCCCC
PIQNIGAYGIELKSVCDYVDLLDLTTGAIDRIAASDCGFGYRESIFKHHFQKGHIIVGVG
CHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEC
LRLSKQWDPMLNYGDLTKLDPETVTPRQVFDSVCAMRRSKLPDPKVTGNAGSFFKNPLVG
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCC
SEKAAELTTEYPGIPHYPQQDGQVKLAAGWLIDQCGLKGHQIGGAAVHNQQALVLVNADN
CCHHHHHHHCCCCCCCCCCCCCCEEEEECEEHHHCCCCCCCCCCEEEECCCEEEEEECCC
AASQDVVALARHVRNTVAKKFDVWLEPEVRFIGAVGELNAVEVLS
CCHHHHHHHHHHHHHHHHHHHCEEECCCEEEEEECCCCCEEEECC
>Mature Secondary Structure 
STESASLKKHNTFALPVNAAHLVIAETIELMIKVWQKTQKRQEPLLVLGEGSNVLFLDD
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEC
FSGTVMINQLKGIDIREEKDAWFLHVSSGENWHGLVCRTLEIGIPGLENLALIPGLVGSA
CCCEEEEEEECCCCEEECCCEEEEEECCCCCCCEEEEEEEEECCCCCCCHHHHCCCCCCC
PIQNIGAYGIELKSVCDYVDLLDLTTGAIDRIAASDCGFGYRESIFKHHFQKGHIIVGVG
CHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEC
LRLSKQWDPMLNYGDLTKLDPETVTPRQVFDSVCAMRRSKLPDPKVTGNAGSFFKNPLVG
EEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCC
SEKAAELTTEYPGIPHYPQQDGQVKLAAGWLIDQCGLKGHQIGGAAVHNQQALVLVNADN
CCHHHHHHHCCCCCCCCCCCCCCEEEEECEEHHHCCCCCCCCCCEEEECCCEEEEEECCC
AASQDVVALARHVRNTVAKKFDVWLEPEVRFIGAVGELNAVEVLS
CCHHHHHHHHHHHHHHHHHHHCEEECCCEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA