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The map label for this gene is fimA [H]

Identifier: 157163758

GI number: 157163758

Start: 4548117

End: 4548671

Strand: Direct

Name: fimA [H]

Synonym: EcHS_A4540

Alternate gene names: 157163758

Gene position: 4548117-4548671 (Clockwise)

Preceding gene: 157163757

Following gene: 157163759

Centisome position: 97.95

GC content: 51.89

Gene sequence:

>555_bases
ATGAAAATTAAAACTCTGGCAATTGTTGTTCTGTCGGCTCTGTCCCTGAGTTCTACAGCGGCTCTGGCTGAAACTACACC
CACGACGGTAAATGGTGGGACCGTTCACTTTAAAGGGGAAGTTGTTAACGCCGCTTGCGCAGTTGATGCAGGCTCTGTTG
ATCAAACCGTTCAGTTGGGCCAGGTTCGTACCGCTAGTCTGAAGCAGACTGGAGCAACCAGCTCTGCTGTCGGTTTTAAC
ATTCAGCTGAATGATTGCGATACCAGTGTTGCCACAAAAGCCGCTGTTGCCTTCTTGGGGACTGCGATTGACAGTGCTCA
TCCTAAAGTACTGGCTCTGCAGAGTTCAGCTGCGGGTAGCGCAACAAACGTTGGTGTGCAGATCCTGGACAGAACGGGTG
CTGCGCTGGCGCTGGACGGTGCGACATTTAGTTCAGAAACAACCCTGAATAACGGAACCAACACCATTCCGTTCCAGGCG
CGTTATTTTGCAACCGGTGCCGCAACCCCGGGTGCTGCTAATGCGGATGCGACCTTCAAGGTTCAGTATCAATAA

Upstream 100 bases:

>100_bases
AAAACTGTGCAGTGTTGGCAGTCAAACTCGTTGACAAAACAAAGTGTACAGAACGACTGCCCATGTCGATTTAGAAATAG
TTTTTTTAAAGGAAAGCAGT

Downstream 100 bases:

>100_bases
CCTACCCAGGTTCAGGGACGTCATTACGGGCAGGGATGCCCACCCTTGTGCGATAAAAATAACGATGAAAAGGAAGAGAT
TATTTCTATTAGCGTCGTTG

Product: type-1 fimbrial protein

Products: NA

Alternate protein names: Type-1A pilin [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKIKTLAIVVLSALSLSSTAALAETTPTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLKQTGATSSAVGFN
IQLNDCDTSVATKAAVAFLGTAIDSAHPKVLALQSSAAGSATNVGVQILDRTGAALALDGATFSSETTLNNGTNTIPFQA
RYFATGAATPGAANADATFKVQYQ

Sequences:

>Translated_184_residues
MKIKTLAIVVLSALSLSSTAALAETTPTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLKQTGATSSAVGFN
IQLNDCDTSVATKAAVAFLGTAIDSAHPKVLALQSSAAGSATNVGVQILDRTGAALALDGATFSSETTLNNGTNTIPFQA
RYFATGAATPGAANADATFKVQYQ
>Mature_184_residues
MKIKTLAIVVLSALSLSSTAALAETTPTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLKQTGATSSAVGFN
IQLNDCDTSVATKAAVAFLGTAIDSAHPKVLALQSSAAGSATNVGVQILDRTGAALALDGATFSSETTLNNGTNTIPFQA
RYFATGAATPGAANADATFKVQYQ

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI1790769, Length=184, Percent_Identity=91.8478260869565, Blast_Score=279, Evalue=7e-77,
Organism=Escherichia coli, GI87081753, Length=157, Percent_Identity=51.5923566878981, Blast_Score=127, Evalue=3e-31,
Organism=Escherichia coli, GI87082421, Length=186, Percent_Identity=34.9462365591398, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87081804, Length=155, Percent_Identity=34.8387096774194, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786938, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=5e-13,
Organism=Escherichia coli, GI1789422, Length=161, Percent_Identity=35.4037267080745, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1786746, Length=170, Percent_Identity=30.5882352941176, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790773, Length=154, Percent_Identity=35.0649350649351, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787174, Length=191, Percent_Identity=31.413612565445, Blast_Score=60, Evalue=9e-11,
Organism=Escherichia coli, GI1787781, Length=153, Percent_Identity=29.4117647058824, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 18424; Mature: 18424

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKTLAIVVLSALSLSSTAALAETTPTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLG
CCCHHHHHHHHHHHCCCCCEEEECCCCCEECCCEEEEECEEEEEEEEECCCCCCCEEEEC
QVRTASLKQTGATSSAVGFNIQLNDCDTSVATKAAVAFLGTAIDSAHPKVLALQSSAAGS
CEEECHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
ATNVGVQILDRTGAALALDGATFSSETTLNNGTNTIPFQARYFATGAATPGAANADATFK
CCCCEEEEEECCCCEEEECCCCCCCCCEECCCCCCCCEEEEEEEECCCCCCCCCCCEEEE
VQYQ
EEEC
>Mature Secondary Structure
MKIKTLAIVVLSALSLSSTAALAETTPTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLG
CCCHHHHHHHHHHHCCCCCEEEECCCCCEECCCEEEEECEEEEEEEEECCCCCCCEEEEC
QVRTASLKQTGATSSAVGFNIQLNDCDTSVATKAAVAFLGTAIDSAHPKVLALQSSAAGS
CEEECHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
ATNVGVQILDRTGAALALDGATFSSETTLNNGTNTIPFQARYFATGAATPGAANADATFK
CCCCEEEEEECCCCEEEECCCCCCCCCEECCCCCCCCEEEEEEEECCCCCCCCCCCEEEE
VQYQ
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8636962; 11251843; 12657207 [H]