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The map label for this gene is idnR [H]

Identifier: 157163739

GI number: 157163739

Start: 4526267

End: 4527265

Strand: Reverse

Name: idnR [H]

Synonym: EcHS_A4520

Alternate gene names: 157163739

Gene position: 4527265-4526267 (Counterclockwise)

Preceding gene: 157163740

Following gene: 157163738

Centisome position: 97.5

GC content: 46.85

Gene sequence:

>999_bases
ATGCGCAATCACAGAATTTCTTTACAGGATATCGCTACGCTGGCTGGCGTAACAAAAATGACCGTGAGTCGTTATATCCG
CTCGCCGAAAAAGGTGGCAAAGGAAACAGGCGAGCGCATCGCCAAAATTATGGAAGAGATCAATTATATCCCTAATCGCG
CTCCCGGCATGTTGTTGAATGCACAAAGTTATACCCTTGGTATCTTGATTCCGTCATTTCAAAATCAACTCTTCGCTGAC
ATTCTCGCGGGAATAGAATCCGTCACCTCTGAGCATAATTATCAGACCCTTATTGCTAATTACAATTACGATCGCGATTC
CGAAGAAGAGTCGGTGATTAACCTGCTCTCTTATAACATTGACGGGATTATACTTTCGGAAAAATATCACACCATCAGGA
CGGTGAAATTTCTGCGTTCAGCCACCATTCCGGTCGTGGAATTGATGGATGTACAGGGAGAACGGCTGGATATGGAGGTC
GGTTTTGATAATCGGCAGGCCGCTTTTGACATGGTGTGTACCATGCTGGAGAAGCGAGTCAGGCACAAAATTCTGTATCT
CGGTTCCAAAGATGACACCCGCGATGAACAGCGTTATCAGGGGTATTGCGATGCGATGATGCTGCATAATCTTTCCCCAT
TACGCATGAATCCACGCGCCATCTCATCCATTCATTTAGGAATGCAGTTAATGCGTGATGCCCTTAGCGCAAACCCGGAT
TTAGACGGTGTATTTTGCACCAATGACGATATTGCGATGGGTGCGCTTCTGCTGTGCCGCGAGCGAAACCTCGCCGTGCC
AGAACAAATTTCCATTGCGGGTTTTCATGGGCTGGAGATTGGCAGGCAAATGATCCCAAGCCTCGCCAGCGTAATTACTC
CCCGTTTTGATATTGGTCGGATGGCCGCCCAAATGTTGCTGAGCAAAATTAAAAATAACGATCACAACCACAACACTGTT
GACCTCGGGTATCAGATTTATCAAGGCAACACGCTTTAG

Upstream 100 bases:

>100_bases
GGGCGTGTTAGCCATTAACGCCGTATTGCACTGAAAGAATAAAATATTGTGATGTAGTTTCGGGGGAAGATTGAAGATTC
CCCCGACGTTGGGAGAAGTT

Downstream 100 bases:

>100_bases
GTTATTTTCTCTTCATTACACGTATTCTCTTTGCCGGACGTTGCCTATACTCCAGGCAGGAAACTGGAGGAAATCTCATG
AGCGAACCCCTGTTAATTGC

Product: transcriptional regulator IdnR

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFAD
ILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV
GFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTV
DLGYQIYQGNTL

Sequences:

>Translated_332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFAD
ILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV
GFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTV
DLGYQIYQGNTL
>Mature_332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFAD
ILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV
GFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTV
DLGYQIYQGNTL

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=99.6987951807229, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI48994940, Length=332, Percent_Identity=46.0843373493976, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=26.517571884984, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789068, Length=295, Percent_Identity=25.4237288135593, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790194, Length=308, Percent_Identity=26.2987012987013, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788474, Length=312, Percent_Identity=26.2820512820513, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789202, Length=315, Percent_Identity=25.7142857142857, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787948, Length=320, Percent_Identity=23.75, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=25.3731343283582, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786268, Length=284, Percent_Identity=26.056338028169, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=20.9375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786540, Length=291, Percent_Identity=22.680412371134, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37559; Mature: 37559

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNI
CCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCC
DGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRV
CEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
HHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
MAAQMLLSKIKNNDHNHNTVDLGYQIYQGNTL
HHHHHHHHHHHCCCCCCCEEEECEEEECCCCC
>Mature Secondary Structure
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNI
CCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCC
DGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRV
CEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
HHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
MAAQMLLSKIKNNDHNHNTVDLGYQIYQGNTL
HHHHHHHHHHHCCCCCCCEEEECEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]