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The map label for this gene is rraB

Identifier: 157163730

GI number: 157163730

Start: 4514757

End: 4515173

Strand: Direct

Name: rraB

Synonym: EcHS_A4511

Alternate gene names: 157163730

Gene position: 4514757-4515173 (Clockwise)

Preceding gene: 157163728

Following gene: 157163732

Centisome position: 97.23

GC content: 49.4

Gene sequence:

>417_bases
ATGGCAAACCCGGAACAACTGGAAGAACAGCGTGAAGAAACACGTTTGATTATTGAAGAATTACTGGAAGATGGCAGCGA
TCCGGACGCGCTGTACACCATCGAACACCATCTTTCCGCAGACGATCTGGAAACCCTGGAAAAAGCAGCAGTTGAAGCGT
TTAAACTCGGTTACGAAGTGACCGATCCAGAAGAGCTGGAAGTTGAAGATGGTGATATCGTGATTTGCTGCGACATCCTC
AGCGAGTGCGCGTTGAATGCCGATCTGATCGATGCCCAGGTTGAACAACTGATGACGCTGGCGGAGAAATTTGACGTTGA
GTACGACGGTTGGGGCACTTACTTTGAAGATCCCAATGGCGAAGACGGCGACGATGAAGATTTTGTCGATGAAGACGATG
ACGGTGTTCGCCACTAA

Upstream 100 bases:

>100_bases
ATTTGCAAGTCTAAAGCATAAATCTTTGTCACAAAGGTGGAGGCAATGTCAGTGGTGTGTGACAATAAGAGTATCGGCAG
GACATTAAGAGGAATGAGCC

Downstream 100 bases:

>100_bases
TTAATTGATTAAAATGCCCGATAGCACACACTAGCGGGCATTTTTTTAGAGTTCGCGTAGCATCCGCACTTCACAATCGA
CATGGCCCGTGCAGCCAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDIL
SECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH

Sequences:

>Translated_138_residues
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDIL
SECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>Mature_137_residues
ANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILS
ECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH

Specific function: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome

COG id: COG3076

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraB family

Homologues:

Organism=Escherichia coli, GI1790704, Length=138, Percent_Identity=100, Blast_Score=271, Evalue=8e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RRAB_ECO57 (P0AF91)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B86124
- PIR:   H91282
- RefSeq:   NP_290888.1
- RefSeq:   NP_313259.1
- ProteinModelPortal:   P0AF91
- SMR:   P0AF91
- MINT:   MINT-1243790
- EnsemblBacteria:   EBESCT00000026130
- EnsemblBacteria:   EBESCT00000059554
- GeneID:   913392
- GeneID:   959782
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5867
- KEGG:   ecs:ECs5232
- GeneTree:   EBGT00050000009936
- HOGENOM:   HBG297993
- OMA:   YTIEHHF
- ProtClustDB:   PRK11191
- BioCyc:   ECOL83334:ECS5232-MONOMER
- HAMAP:   MF_01888
- InterPro:   IPR009671
- InterPro:   IPR016716
- Gene3D:   G3DSA:3.30.70.970
- PIRSF:   PIRSF018193

Pfam domain/function: PF06877 DUF1260; SSF89946 DUF1260

EC number: NA

Molecular weight: Translated: 15603; Mature: 15472

Theoretical pI: Translated: 3.41; Mature: 3.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCC
TDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNG
CCCCCEEECCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EDGDDEDFVDEDDDGVRH
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCC
TDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNG
CCCCCEEECCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EDGDDEDFVDEDDDGVRH
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796