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The map label for this gene is yhjC [H]

Identifier: 157163000

GI number: 157163000

Start: 3713726

End: 3714625

Strand: Direct

Name: yhjC [H]

Synonym: EcHS_A3724

Alternate gene names: 157163000

Gene position: 3713726-3714625 (Clockwise)

Preceding gene: 157162998

Following gene: 157163001

Centisome position: 79.98

GC content: 53.0

Gene sequence:

>900_bases
ATGGATAAAATTCACGCAATGCAGTTGTTCATCAAAGTCGCGGAGCTGGAAAGTTTTTCCCGCGCGGCGGATTTCTTTGC
TTTGCCAAAGGGAAGTGTTTCGCGCCAGATACAGGCACTGGAACATCAACTTGGCACCCAGCTTCTCCAGCGCACTACGC
GACGGGTCAAACTCACGCCAGAAGGCATGACCTATTATCAACGGGCAAAAGATGTGTTGAGTAATCTCAGCGAACTGGAC
GGTCTGTTTCAACAGGATGCCACCAGTATCAGCGGTAAATTACGCATCGACATCCCGTCAGGAATCGCGAAAAACCTGTT
ACTGCCGCGTCTGTCGGAATTTCTCTATCAGCATCCGGGAATTGAGCTGGAACTGAGTAGCCATAACCGTCCGGTAGATA
TTCTTCATGATGGTTTTGATTGCGTGATACGCACTGGCGCGTTACCGGAAGATGGCGTTATCGCCCGTCCCCTCGGCAAA
CTGACCATGGTCAACTGTGCCAGTCCGCACTATCTGACGCGCTTTGGTTATCCGCAAAGCCCCGATGATCTGACTTCACA
CGCAATAGTGCGTTATACACCGCATCTGGGTGTACATCCGTTAGGTTTTGAGGTTGCCAGCGTTAATGGCGTCCAGTGGT
TTAAGTCTGGCGGCATGTTGACGGTAAACAGTAGCGAAAACTATCTCGCCGCCGGTCTTGCCGGTCTGGGGATTATTCAG
ATCCCGCGCATTGCCGTGCGCGAAGCCCTGCGTGCCGGGCGGCTTATTGAAGTATTACCTGGCTACCGTGCCGAGCCGCT
CTCCCTTTCGCTGGTTTATCCGCAGCGTCGGGAGCTTTCCCGGCGTGTAAACCTGTTTATGCAGTGGCTGGCTGGCGTAA
TGAAAGAGTACCTGGACTGA

Upstream 100 bases:

>100_bases
ATGACAACATTGTGAAACCCGGCATTAGATGTTAGAAAAAACAATAAACAATGCGATATGCGCGTTACTGTTTCGCTGTG
AACAACAATCGGTCAAAGAA

Downstream 100 bases:

>100_bases
CCGACTATACTTTTTAAGAATGACCACGACAGAAGGACAAAAGAGCGGATGACGCAGGAAAACGAGATCAAACGTCCCAT
CCAGGATCTGGAGCACGAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELD
GLFQQDATSISGKLRIDIPSGIAKNLLLPRLSEFLYQHPGIELELSSHNRPVDILHDGFDCVIRTGALPEDGVIARPLGK
LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLAAGLAGLGIIQ
IPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMKEYLD

Sequences:

>Translated_299_residues
MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELD
GLFQQDATSISGKLRIDIPSGIAKNLLLPRLSEFLYQHPGIELELSSHNRPVDILHDGFDCVIRTGALPEDGVIARPLGK
LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLAAGLAGLGIIQ
IPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMKEYLD
>Mature_299_residues
MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELD
GLFQQDATSISGKLRIDIPSGIAKNLLLPRLSEFLYQHPGIELELSSHNRPVDILHDGFDCVIRTGALPEDGVIARPLGK
LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLAAGLAGLGIIQ
IPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMKEYLD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=98.3277591973244, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=31.438127090301, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=29.3515358361775, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=28.4246575342466, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=28.0141843971631, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=28.7625418060201, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=28.0936454849498, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789173, Length=296, Percent_Identity=26.6891891891892, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1786448, Length=282, Percent_Identity=25.177304964539, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790011, Length=294, Percent_Identity=23.1292517006803, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790399, Length=160, Percent_Identity=30.625, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=26.643598615917, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33331; Mature: 33331

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECC
EGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPSGIAKNLLLPRLSEFLYQHPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
IELELSSHNRPVDILHDGFDCVIRTGALPEDGVIARPLGKLTMVNCASPHYLTRFGYPQS
CEEEECCCCCCCHHHCCCHHHEEECCCCCCCCEEECCCCCEEEEECCCCCHHHHCCCCCC
PDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLAAGLAGLGIIQ
CHHHHHCEEEEECCCCCCCCCCEEEEECCCCHHCCCCCEEEECCCCCEEHHHHHHCCHHH
IPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMKEYLD
CCHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECC
EGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPSGIAKNLLLPRLSEFLYQHPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
IELELSSHNRPVDILHDGFDCVIRTGALPEDGVIARPLGKLTMVNCASPHYLTRFGYPQS
CEEEECCCCCCCHHHCCCHHHEEECCCCCCCCEEECCCCCEEEEECCCCCHHHHCCCCCC
PDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLAAGLAGLGIIQ
CHHHHHCEEEEECCCCCCCCCCEEEEECCCCHHCCCCCEEEECCCCCEEHHHHHHCCHHH
IPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMKEYLD
CCHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]