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The map label for this gene is ugpQ [H]

Identifier: 157162925

GI number: 157162925

Start: 3633628

End: 3634371

Strand: Reverse

Name: ugpQ [H]

Synonym: EcHS_A3646

Alternate gene names: 157162925

Gene position: 3634371-3633628 (Counterclockwise)

Preceding gene: 157162926

Following gene: 157162923

Centisome position: 78.27

GC content: 56.45

Gene sequence:

>744_bases
ATGAGTAACTGGCCTTATCCCCGCATCGTCGCTCATCGTGGCGGCGGTAAGCTGGCCCCGGAAAACACCCTGGCGGCAAT
CGACGTCGGGGCAAAATACGGTCATAAGATGATCGAATTTGACGCGAAGTTATCGAAAGATGGCGAGATCTTCCTGCTCC
ATGACGACAATCTCGAACGCACCAGCAACGGCTGGGGCGTCGCGGGTGAACTGAACTGGCAGGATTTACTGCGCGTGGAT
GCGGGCAGTTGGTACAGCAAAGCGTTTAAAGGTGAGCCGCTGCCGTTGCTTTCGCAGGTGGCGGAACGCTGTCGTGAACA
CGGGATGATGGCGAATATCGAAATCAAACCCACCATTGGCACTGGACCATTAACGGGCAAAATGGTGGCGCTGGCGGCAC
GCCAACTGTGGGCCGGTATGACGCCGCCGCTGCTGTCATCGTTTGAGATTGATGCTTTAGAAGCCGCACAACAGGCAGTA
CCGGAACTGCCGCGCGGTTTGTTGCTGGATGAGTGGCGCGACGACTGGCGCGAACTGACCGCGCGGCTGGGCTGCGTCTC
TATTCATCTCAATCATAAGTTACTCGATAAAGTGCGAGTGATGCAGTTGAAAGACGCCGGACTGCGGATTCTGGTTTATA
CCGTCAATAAACCCCAGCGCGCGGCAGAGTTGCTGCGCTGGGGCGTGGATTGCATCTGTACCGATGCGATTGACGTGATT
GGTCCGAACTTTACGGCCCAATAG

Upstream 100 bases:

>100_bases
GACTGGCGCATCAGGAGCGCCCGACGGCAGGCAGCACGCTGTGGCTGCATCTGGCGGAAAATCAGCTGCATCTTTTTGAT
GGTGAAACAGGACAACGAGT

Downstream 100 bases:

>100_bases
TTTTCAACGGAATGTCAGGCTGCGGCGTGCTGGGCTGATTCAGCATGTCGCCGTTTCTCCTCTCCGGCAGCATATGCTGC
TGATTCAACGAACTATCCGG

Product: cytoplasmic glycerophosphodiester phosphodiesterase

Products: NA

Alternate protein names: Glycerophosphodiester phosphodiesterase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVD
AGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTIGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQQAV
PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
GPNFTAQ

Sequences:

>Translated_247_residues
MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVD
AGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTIGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQQAV
PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
GPNFTAQ
>Mature_246_residues
SNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDA
GSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTIGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQQAVP
ELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVIG
PNFTAQ

Specific function: Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols [H]

COG id: COG0584

COG function: function code C; Glycerophosphoryl diester phosphodiesterase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family [H]

Homologues:

Organism=Homo sapiens, GI284055245, Length=89, Percent_Identity=40.4494382022472, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI284055240, Length=89, Percent_Identity=40.4494382022472, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI284055242, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI7706617, Length=116, Percent_Identity=34.4827586206897, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI21361649, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1789858, Length=247, Percent_Identity=97.165991902834, Blast_Score=497, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004129
- InterPro:   IPR017946 [H]

Pfam domain/function: PF03009 GDPD [H]

EC number: =3.1.4.46 [H]

Molecular weight: Translated: 27402; Mature: 27271

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLER
CCCCCCCEEEEECCCCCCCCCCCEEEEECCHHHCCEEEEECCCCCCCCCEEEEECCCCCC
TSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTIG
CCCCCCEEEECCHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
TGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQQAVPELPRGLLLDEWRDDWRELT
CCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
HHHCEEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEHHHHHHH
GPNFTAQ
CCCCCCC
>Mature Secondary Structure 
SNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLER
CCCCCCEEEEECCCCCCCCCCCEEEEECCHHHCCEEEEECCCCCCCCCEEEEECCCCCC
TSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAERCREHGMMANIEIKPTIG
CCCCCCEEEECCHHHHHEECCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCCC
TGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQQAVPELPRGLLLDEWRDDWRELT
CCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
HHHCEEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEHHHHHHH
GPNFTAQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2541415; 1851953; 8041620; 9278503; 3062310 [H]