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The map label for this gene is fic [H]

Identifier: 157162838

GI number: 157162838

Start: 3535204

End: 3535806

Strand: Reverse

Name: fic [H]

Synonym: EcHS_A3558

Alternate gene names: 157162838

Gene position: 3535806-3535204 (Counterclockwise)

Preceding gene: 157162839

Following gene: 157162837

Centisome position: 76.14

GC content: 53.4

Gene sequence:

>603_bases
ATGAGCGATAAATTCGGCGAAGGGCGCGATCCGTATCTTTATCCTGGCCTTGATATCATGCGTAACCGGCTGAACATCCA
CCAGCAGCAGCGGCTGGAACAGGCCGCTTACGAAATGACGGCGCTGCGTGCTGCGACCATTGAGCTTGGTCCGCTGGTGC
GCGGTTTACCGCATTTGCGCACTATCCATCGCCAGCTGTATCAGGATATTTTCGACTGGGCGGGGCAACTGCGTGAAGTT
GATATTTATCAGGGCGATACGCCGTTCTGCCACTTTGCTTATATCGAAAAAGAGGGCAATGCCCTGATGCAGGATCTGGA
GGAAGAAGGTTATCTGGTTGGCCTGGAGAAAGCGAAGTTCGTCGAGCGGCTGGCGCATTACTATTGTGAAATCAACGTGC
TGCATCCCTTCCGTGTGGGAAGCGGACTGGCACAGCGGATCTTCTTCGAGCAACTGGCGATTCATGCCGGATATCAACTG
AGCTGGCAGGGTATCGAAAAAGAAGCCTGGAATCAGGCAAATCAGAGTGGGGCAATGGGGGATCTCACCGCGCTGCAGAT
GATATTTAGCAAAGTGGTAAGCGAAGCCGGGGAATCTGAGTAA

Upstream 100 bases:

>100_bases
AATTTCCAGGCCAGTCGCCGTCTTGAAGGCGTCGAGATGCCTTTAGTCACTCTTACTGCCGCAGAGGCTTTAGCGCGCCT
TGAAGAGCTGAGGAGGCACT

Downstream 100 bases:

>100_bases
AATAGCGTGGTTCTTTCGTACCGGAGCCGCCATGATCCTGCTTATAGATAACTACGATTCTTTTACCTGGAACCTCTACC
AGTACTTTTGTGAACTGGGG

Product: cell filamentation protein Fic

Products: NA

Alternate protein names: Cell filamentation protein fic [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSDKFGEGRDPYLYPGLDIMRNRLNIHQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREV
DIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE

Sequences:

>Translated_200_residues
MSDKFGEGRDPYLYPGLDIMRNRLNIHQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREV
DIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE
>Mature_199_residues
SDKFGEGRDPYLYPGLDIMRNRLNIHQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVD
IYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLS
WQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE

Specific function: Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Involved in cell filamentation induced by cyclic AMP. May have some role in cell division [H]

COG id: COG2184

COG function: function code D; Protein involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fido domain [H]

Homologues:

Organism=Escherichia coli, GI1789761, Length=200, Percent_Identity=99.5, Blast_Score=412, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003812 [H]

Pfam domain/function: PF02661 Fic [H]

EC number: NA

Molecular weight: Translated: 22941; Mature: 22810

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKFGEGRDPYLYPGLDIMRNRLNIHQQQRLEQAAYEMTALRAATIELGPLVRGLPHLR
CCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKF
HHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEEHHHHHH
VERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLSWQGIEKEAWNQANQSGAMG
HHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCH
DLTALQMIFSKVVSEAGESE
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDKFGEGRDPYLYPGLDIMRNRLNIHQQQRLEQAAYEMTALRAATIELGPLVRGLPHLR
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKF
HHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEEHHHHHH
VERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLSWQGIEKEAWNQANQSGAMG
HHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCH
DLTALQMIFSKVVSEAGESE
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2546924; 2403545; 9278503; 7549107; 2007139 [H]