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The map label for this gene is lptC

Identifier: 157162683

GI number: 157162683

Start: 3393763

End: 3394338

Strand: Direct

Name: lptC

Synonym: EcHS_A3392

Alternate gene names: 157162683

Gene position: 3393763-3394338 (Clockwise)

Preceding gene: 157162682

Following gene: 157162684

Centisome position: 73.09

GC content: 46.53

Gene sequence:

>576_bases
ATGAGTAAAGCCAGACGTTGGGTTATCATTGTGCTATCACTGGCGGTTCTGGTGATGATCGGCATTAATATGGCCGAAAA
AGACGATACCGCCCAGGTGGTCGTCAACAACAATGATCCCACCTATAAAAGCGAGCATACGGACACGCTCGTCTATAACC
CAGAAGGGGCACTAAGCTATCGATTGATTGCTCAACACGTTGAATATTATTCCGATCAGGCCGTTTCGTGGTTTACGCAG
CCGGTACTTACCACGTTTGATAAGGATAAAATCCCGACATGGTCCGTAAAAGCAGATAAAGCCAAGCTGACCAATGACCG
GATGCTCTATTTATATGGACACGTTGAAGTCAACGCACTTGTGCCGGACTCTCAACTTCGCAGAATCACGACGGATAACG
CGCAGATCAATCTGGTGACGCAGGATGTTACCTCTGAAGACCTCGTCACGTTATACGGAACAACATTTAACTCCAGCGGT
CTGAAAATGCGCGGCAACTTACGCAGCAAGAACGCCGAGCTGATTGAAAAGGTTAGAACATCCTATGAAATTCAAAACAA
ACAAACTCAGCCTTAA

Upstream 100 bases:

>100_bases
ACGTGACGCGCATTGCTGGCGGTCGTGGCGCAGTGCGCGAAGTTTGCGACTTATTACTCCTGGCGCAGGGCAAACTGGAT
GAAGCCAAAGGGCAATCGAT

Downstream 100 bases:

>100_bases
TCTTGTGCTTGCCAGCTCACTTCTGGCCGCCAGCATTCCGGCATTTGCCGTAACCGGAGACACTGATCAGCCGATCCACA
TTGAATCGGACCAGCAATCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKSEHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQ
PVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP

Sequences:

>Translated_191_residues
MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKSEHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQ
PVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP
>Mature_190_residues
SKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKSEHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQP
VLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSGL
KMRGNLRSKNAELIEKVRTSYEIQNKQTQP

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane

COG id: COG3117

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptC family

Homologues:

Organism=Escherichia coli, GI1789591, Length=191, Percent_Identity=100, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPTC_ECO57 (P0ADW1)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A85984
- PIR:   F91138
- RefSeq:   NP_289773.1
- RefSeq:   NP_312105.1
- ProteinModelPortal:   P0ADW1
- SMR:   P0ADW1
- EnsemblBacteria:   EBESCT00000028946
- EnsemblBacteria:   EBESCT00000058463
- GeneID:   916076
- GeneID:   958638
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4562
- KEGG:   ecs:ECs4078
- GeneTree:   EBGT00050000009327
- HOGENOM:   HBG391182
- OMA:   YWQVQSK
- ProtClustDB:   PRK10893
- BioCyc:   ECOL83334:ECS4078-MONOMER
- InterPro:   IPR010664

Pfam domain/function: PF06835 DUF1239

EC number: NA

Molecular weight: Translated: 21703; Mature: 21572

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17acbde4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKSEHTDTLVYNPEGALSY
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHH
RLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVEVNAL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCCCEEEEEEEEEEEEEE
VPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSGLKMRGNLRSKNAELIEKVRT
CCHHHHHEEECCCCEEEEEECCCCCCCEEEEEECEECCCCCEEECCCCCCCHHHHHHHHH
SYEIQNKQTQP
HHEECCCCCCH
>Mature Secondary Structure 
SKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKSEHTDTLVYNPEGALSY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHH
RLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVEVNAL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEECCCCEEEEEEEEEEEEEE
VPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSGLKMRGNLRSKNAELIEKVRT
CCHHHHHEEECCCCEEEEEECCCCCCCEEEEEECEECCCCCEEECCCCCCCHHHHHHHHH
SYEIQNKQTQP
HHEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796