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The map label for this gene is qseB [H]

Identifier: 157162501

GI number: 157162501

Start: 3214659

End: 3215318

Strand: Direct

Name: qseB [H]

Synonym: EcHS_A3203

Alternate gene names: 157162501

Gene position: 3214659-3215318 (Clockwise)

Preceding gene: 157162491

Following gene: 157162502

Centisome position: 69.23

GC content: 52.12

Gene sequence:

>660_bases
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGACCCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Upstream 100 bases:

>100_bases
TAACAACTTCTTAAGGGAAAAAAATAAAATTTAGTGCTGTACAGAGCGCGTTACAACACGGTTTACTGGCAGCAAATACG
GTTATCGCAGGGATGAAAAA

Downstream 100 bases:

>100_bases
AATTTACCCAACGTCTTAGTCTGCGCGTCAGGCTGACGCTAATCTTTTTAATTCTGGCCTCGGTGACCTGGCTGCTTTCC
AGCTTTGTCGCCTGGAAACA

Product: DNA-binding transcriptional regulator QseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGDPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Sequences:

>Translated_219_residues
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGDPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK
>Mature_219_residues
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGDPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=99.0867579908676, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=45.8333333333333, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=40.3587443946188, Blast_Score=160, Evalue=4e-41,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=37.2727272727273, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=34.4036697247706, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=35.1351351351351, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=33.1818181818182, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.6491228070175, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=30.3964757709251, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=26.9058295964126, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.6943231441048, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.7610619469027, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=34.5794392523364, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=32.7731092436975, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI48994928, Length=128, Percent_Identity=33.59375, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24674; Mature: 24674

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGR
CEEEEEECCEEECCCHHHHHHHHCCCEEHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCH
DILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTN
HHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASNELRHGNVMLDPGKRIATLAGDPLTLKPKEFALLELLMRNAGRVLPRKLIEEKLYT
CCCCCCCCCCCEEECCCCEEEEECCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
WDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGR
CEEEEEECCEEECCCHHHHHHHHCCCEEHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCH
DILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTN
HHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASNELRHGNVMLDPGKRIATLAGDPLTLKPKEFALLELLMRNAGRVLPRKLIEEKLYT
CCCCCCCCCCCEEECCCCEEEEECCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
WDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]