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The map label for this gene is sorE

Identifier: 157162390

GI number: 157162390

Start: 3103690

End: 3104967

Strand: Reverse

Name: sorE

Synonym: EcHS_A3089

Alternate gene names: 157162390

Gene position: 3104967-3103690 (Counterclockwise)

Preceding gene: 157162391

Following gene: 157162389

Centisome position: 66.87

GC content: 50.94

Gene sequence:

>1278_bases
ATGAAAACCAAAGTTGCTGCTATTTATGGCAAGCGGGATGTCCGTCTGCGCGTATTTGAACTGCCAGAAATTACCGATAA
TGAATTACTGGTGAGTGTAATTTCTGACAGCGTCTGTTTATCGACCTGGAAAGCGGCGTTACTCGGTAGTGAACATAAAC
GCGTACCCGACGATTTAGAAAATCATCCGGTCATTACCGGGCATGAATGTGCCGGGGTTATTGTCGAAGTGGGTAAAAAT
CTCACTGGCAAATATAAAAAAGGCCAGCGTTTTGTATTGCAACCGGCGATGGGGTTACCAAGCGGATATTCAGCGGGCTA
CAGCTACGAATATTTTGGCGGCAATGCCACTTATATGATTATTCCCGAAATCGCCATTAATTTGGGCTGCGTATTACCGT
ATCACGGCTCTTATTTTGCTGCGGCGTCGCTGGCAGAGCCTATGTGCTGCATTATTGGTGCTTATCATGCCAATTATCAC
ACCACGCAATATGTTTATGAGCATCGCATGGGCGTCAAACCTGGCGGCAATATTGCACTGCTGGCGTGTGCAGGTCCGAT
GGGCATTGGCGCTATCGATTACGCCATTAACGGCGGCATACAACCGTCGCGGGTGGTGGTGGTCGATATCGACGACAAAC
GTCTGGCGCAGGTACAGAAGCTGCTGCCGGTGGAACTGGCGGCCAGTAAAGGCATTGAGCTGGTGTATGTGAATACCAAA
GGGATGAGCGATCCTGTCCAGATGCTGCGGGCGCTGACAGGAGATGCCGGGTTCGATGACATTTTTGTTTATGCGGCGGT
GCCTGCTGTCGTTGAGATGGCTGATGAATTACTGGCGGAAGATGGCTGTCTGAACTTCTTTGCCGGGCCGACGGATAAAA
ACTTCAAAGTGCCGTTTAATTTCTACAACGTCCATTACAACAGCACGCACGTCGTCGGTACATCTGGCGGTTCAACGGAC
GACATGAAAGAGGCGATTGCCCTTAGCGCCACTGGGCAGTTACAGCCGTCGTTTATGGTGACCCATATCGGTGGCCTGGA
TGCGGTGCCAGAAACCGTGCTCAATCTGCCGGATATCCCTGGCGGTAAAAAACTCATTTATAACGGCGTGACCATGCCGC
TCACTGCCATTGCCGATTTTGCCGAAAAAGGCAAAACCGATCCGCTGTTTAAAGAGTTGGCGCGGCTGGTTGAGGAAACG
CACGGCATCTGGAATGAACAGGCCGAGAAATATCTGCTGGCACAATTTGGCGTTGATATCGGGGAGGCCGCGCAATGA

Upstream 100 bases:

>100_bases
AACCACTGATATTGATTAATAACTATATTGGCGATCCAAAACTCGACACTTTATTTAATCAATTAACCGCCGAACATAAA
CACTGATTACAGAGGTAAAA

Downstream 100 bases:

>100_bases
TGTCCCTGGCGTGGCCATTATTTCGCGTTACGGAACAGGCAGCGTTGGCTGCCTGGCCGCAAACCGGATGTGGCGACAAA
AATAAAATTGATGGCCTGGC

Product: L-sorbose 1-phosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKN
LTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVELAASKGIELVYVNTK
GMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTD
DMKEAIALSATGQLQPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEET
HGIWNEQAEKYLLAQFGVDIGEAAQ

Sequences:

>Translated_425_residues
MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKN
LTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVELAASKGIELVYVNTK
GMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTD
DMKEAIALSATGQLQPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEET
HGIWNEQAEKYLLAQFGVDIGEAAQ
>Mature_425_residues
MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKN
LTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVELAASKGIELVYVNTK
GMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTD
DMKEAIALSATGQLQPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEET
HGIWNEQAEKYLLAQFGVDIGEAAQ

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae sorE

Homologues:

Organism=Escherichia coli, GI48994910, Length=425, Percent_Identity=100, Blast_Score=875, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGGP_ECOLI (P52048)

Other databases:

- EMBL:   U28377
- EMBL:   U28377
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_003489.1
- RefSeq:   YP_026187.1
- ProteinModelPortal:   P52048
- STRING:   P52048
- EnsemblBacteria:   EBESCT00000003742
- EnsemblBacteria:   EBESCT00000015817
- GeneID:   2847686
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5477
- KEGG:   eco:b4465
- EchoBASE:   EB2802
- EcoGene:   EG12976
- eggNOG:   COG1063
- GeneTree:   EBGT00050000009644
- HOGENOM:   HBG305343
- OMA:   HIVGTSG
- ProtClustDB:   CLSK880532
- BioCyc:   EcoCyc:G7520-MONOMER
- Genevestigator:   P52048
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11695

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 45818; Mature: 45818

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLE
CCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCC
NHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMI
CCCEEECCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEEE
IPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYHTTQYVYEHRMGVKPGGNIAL
ECCCEECEEEEECCCCCCHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHCCCCCCCCEEE
LACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVELAASKGIELVYVNTK
EEECCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHCCCEEEEEEECC
GMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFN
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEE
FYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQLQPSFMVTHIGGLDAVPETVLNLPDIP
EEEEEECCEEEEECCCCCCHHHHHHHEEECCCCCCCCEEEEECCCCCHHHHHHHCCCCCC
GGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEETHGIWNEQAEKYLLAQFGVDI
CCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GEAAQ
CCCCC
>Mature Secondary Structure
MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLE
CCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCC
NHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMI
CCCEEECCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEEEE
IPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYHTTQYVYEHRMGVKPGGNIAL
ECCCEECEEEEECCCCCCHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHCCCCCCCCEEE
LACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVELAASKGIELVYVNTK
EEECCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHCCCEEEEEEECC
GMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADELLAEDGCLNFFAGPTDKNFKVPFN
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEE
FYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQLQPSFMVTHIGGLDAVPETVLNLPDIP
EEEEEECCEEEEECCCCCCHHHHHHHEEECCCCCCCCEEEEECCCCCHHHHHHHCCCCCC
GGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEETHGIWNEQAEKYLLAQFGVDI
CCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
GEAAQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503