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The map label for this gene is yfdE

Identifier: 157161844

GI number: 157161844

Start: 2519428

End: 2520573

Strand: Reverse

Name: yfdE

Synonym: EcHS_A2508

Alternate gene names: 157161844

Gene position: 2520573-2519428 (Counterclockwise)

Preceding gene: 157161845

Following gene: 157161841

Centisome position: 54.28

GC content: 45.46

Gene sequence:

>1146_bases
ATGACAAATAATGAAAGCAAAGGCCCGTTTGAAGGCTTATTAGTTATCGATATGACACATGTCCTTAATGGACCTTTCGG
AACTCAACTTCTTTGTAATATGGGCGCAAGGGTAATTAAAGTTGAGCCGCCGGGTCATGGTGATGATACCCGCACATTTG
GTCCCTATGTGGATGGACAGTCACTCTATTACAGTTTTATTAATCATGGCAAAGAGAGTGTGGTTCTTGATTTAAAGAAT
GATCACGATAAAAGTATATTTATAAATATGCTCAAACAAGCTGATGTATTAGCTGAGAATTTTCGCCCAGGTACAATGGA
AAAACTGGGGTTTTCATGGGAAACGCTTCAAGAAATCAACCCGCGCCTCATATATGCTTCATCGTCAGGTTTCGGACATA
CCGGTCCGCTAAAAGATGCTCCTGCCTACGATACCATCATTCAGGCAATGAGCGGGATAATGATGGAAACAGGATATCCT
GATGCTCCGCCAGTGCGCGTTGGTACATCTCTTGCGGATCTATGCGGCGGTGTCTATTTATTCAGCGGAATAGTGAGTGC
ACTTTATGGCCGTGAAAAGAGCCAGAGAGGGGCGCATGTCGATATAGCGATGTTTGATGCCACGCTGAGTTTTCTGGAGC
ATGGTCTGATGGCATATATCGCGACAGGGAAGTCACCACAACGTCTGGGAAATCGCCATCCCTACATGGCACCTTTTGAT
GTTTTCAATACTCAGGATAAGCCGATTACGATTTGTTGTGGTAATGACAAGCTTTTTTCTGCGTTATGCCAGGCACTGGA
GCTTACGGAACTGGTTAATGATCCCCGATTTAGCAGCAATATTTTACGCGTACAAAACCAGGCTATTCTTAAACAATATA
TTGAGCGGACGTTAAAAACGCAGGCAGCTGAAGTTTGGTTAGCCAGAATACATGAAGTTGGTGTACCCGTCGCGCCGTTA
TTAAGTGTGGCTGAGGCCATTAAATTGCCACAAACTCAGGCGAGAAATATGTTGATTGAAGCCGGGGGAATAATGATGCC
GGGTAATCCGATAAAAATCAGCGGCTGCGCGGACCCGCATGTTATGCCGGGAGCGGCAACGCTCGACCAGCATGGGGAAC
AAATTCGCCAGGAGTTCTCATCATAA

Upstream 100 bases:

>100_bases
ATTTATGTCAGTCGACTGGTTTCATAATTAATCATGTTATTGATTTTACATAAATGCCGAAGTGTCTTTTCACCTTCGGC
TTTTTTCAAGGCATAAGCAA

Downstream 100 bases:

>100_bases
ATGTAAGATGTGCTGGTAAATAGCTCCCACATTTGAACATTGTGGGAGCCGCTATTTAGTCATTTTTCTGACAGAAAACA
GCAATCTCCTGGTCCAGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKN
DHDKSIFINMLKQADVLAENFRPGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
VFNTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPL
LSVAEAIKLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS

Sequences:

>Translated_381_residues
MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKN
DHDKSIFINMLKQADVLAENFRPGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
VFNTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPL
LSVAEAIKLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS
>Mature_380_residues
TNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKND
HDKSIFINMLKQADVLAENFRPGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPD
APPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFDV
FNTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPLL
SVAEAIKLPQTQARNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family

Homologues:

Organism=Homo sapiens, GI300863128, Length=376, Percent_Identity=32.9787234042553, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI300863124, Length=324, Percent_Identity=34.5679012345679, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI13376042, Length=324, Percent_Identity=31.1728395061728, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI300863126, Length=376, Percent_Identity=29.7872340425532, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI266458393, Length=200, Percent_Identity=35, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI266458397, Length=200, Percent_Identity=35, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI42794625, Length=200, Percent_Identity=35, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI266456254, Length=200, Percent_Identity=35, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI42822893, Length=143, Percent_Identity=37.7622377622378, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI266458395, Length=143, Percent_Identity=37.7622377622378, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI87082093, Length=381, Percent_Identity=100, Blast_Score=794, Evalue=0.0,
Organism=Escherichia coli, GI1788717, Length=401, Percent_Identity=29.925187032419, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786222, Length=364, Percent_Identity=24.7252747252747, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564160, Length=211, Percent_Identity=28.436018957346, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115535051, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648431, Length=333, Percent_Identity=32.1321321321321, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24585488, Length=335, Percent_Identity=28.6567164179104, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFDE_ECOLI (P76518)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   D14008
- PIR:   H65010
- RefSeq:   AP_002971.1
- RefSeq:   NP_416872.4
- ProteinModelPortal:   P76518
- SMR:   P76518
- DIP:   DIP-11994N
- MINT:   MINT-1289026
- STRING:   P76518
- EnsemblBacteria:   EBESCT00000004970
- EnsemblBacteria:   EBESCT00000016664
- GeneID:   946432
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2368
- KEGG:   eco:b2371
- EchoBASE:   EB3069
- EcoGene:   EG13284
- eggNOG:   COG1804
- GeneTree:   EBGT00050000009654
- HOGENOM:   HBG659028
- OMA:   NIVASQP
- ProtClustDB:   PRK11430
- BioCyc:   EcoCyc:G7234-MONOMER
- Genevestigator:   P76518
- InterPro:   IPR003673
- Gene3D:   G3DSA:3.40.50.10540
- PANTHER:   PTHR11837

Pfam domain/function: PF02515 CoA_transf_3; SSF89796 CoA-Trfase_fam_III

EC number: NA

Molecular weight: Translated: 41671; Mature: 41540

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQ
CCCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCH
SLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRPGTMEKLGFSWETLQEIN
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHCC
PRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPPVRVGTSLADLCGGVYL
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCHHCCHHHHHHHHHHH
FSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
HHHHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCHH
VFNTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKT
HCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAAEVWLARIHEVGVPVAPLLSVAEAIKLPQTQARNMLIEAGGIMMPGNPIKISGCADPH
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCEEECCCCEEEECCCCCC
VMPGAATLDQHGEQIRQEFSS
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQ
CCCCCCCCCCCEEEEEEHHHHCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCH
SLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFRPGTMEKLGFSWETLQEIN
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHCC
PRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPPVRVGTSLADLCGGVYL
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCHHCCHHHHHHHHHHH
FSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRLGNRHPYMAPFD
HHHHHHHHHCCCHHCCCCEEEEHHHHHHHHHHHHHHHEEEECCCCHHHHCCCCCCCCCHH
VFNTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKT
HCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAAEVWLARIHEVGVPVAPLLSVAEAIKLPQTQARNMLIEAGGIMMPGNPIKISGCADPH
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHEEEECCCEEECCCCEEEECCCCCC
VMPGAATLDQHGEQIRQEFSS
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343