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The map label for this gene is yddA [H]

Identifier: 157160972

GI number: 157160972

Start: 1594480

End: 1596165

Strand: Reverse

Name: yddA [H]

Synonym: EcHS_A1581

Alternate gene names: 157160972

Gene position: 1596165-1594480 (Counterclockwise)

Preceding gene: 157160973

Following gene: 157160971

Centisome position: 34.37

GC content: 43.18

Gene sequence:

>1686_bases
ATGATAACCATTCCCATTACGCTTCGTATGTTGATAGCAAAGTATCTCTGTCTGTTGAAGCCCTTTTGGCTGCGTAAGAA
TAATAAAACTTCAGTGTTGTTAATCATTATTATCCTCGCAATGATCCTTGGCGTGGTTAAAATTCAGGTCTGGTTAAACG
ACTGGAATAATGATTTTTTCAATGCGCTAAGCCAGAAAGAAACCGATAAGCTTTGGCAGCTTGTCCTTTGGTTCCCTGCC
TTGCTGGGGATCTTTGTATTAATATCCGTAAACAAAACATGGTTAATTAAACTGCTGACTATTCGCTGGCGCGAATGGTT
AACAGATTACTACCTTAATCGGTGGTTTGCAGATAAAAACTACTACTTCACGCAGATCTACGGCGAGCATAAAAATACAG
ATAACCCTGACCAACGTATCGCTGAAGACATTCTCTTACTGATCAGCAAAACGCTCAGTCTTTCATTTGGCTTCATCCAG
TCACTTAGCATGCTGATCACCTTTACCGTTATTCTTTGGCAAAGCGCGGGTACGCTCTCATTCACTGTTGGTGGAACAGA
ATGGAATATCCAGGGGTATATGGTCTATACCGTCGTGCTCATTGTGATCGGTGGAACTTTATTTACCCATAAGGTGGGTA
AACGTATTCGTCCGCTTAATGTGGAAAAACAACGTAGCGAAGCGACATTTCGAACTAATCTTGTGCAGCATAATAAACAG
GCAGAACTGATTGCGCTAAGCAATGCTGAGTCTCTACAACGCCAGGAGTTGAGCGACAATTTTCATACCATTAAAGAGAA
CTGGCATCGTTTAATGAATCGTCAGCGGTGGCTTGATTACTGGCAAAATATTTATTCGCGCTCGCTTAGCGTTCTTCCCT
ACTTTCTGTTATTGCCGCAGTTTATTAGCGGGCAGATCAATCTGGGCGGACTGATGAAATCGCGCCAGGCATTTATGCTG
GTATCGAACAATTTAAGCTGGTTTATTTATAAATATGACGAACTTGCTGAACTGGCTGCGGTTATCGATCGCTTGTATGA
GTTCCATCAACTCACTGAACAGCGCCCTACGAATAAGCCTAAAAATTGCCAACATGCGGTACAAGTGGCTGATGCGAGTA
TTCGTACGCCTGATAATAAGATCATATTAGAGAACCTAAACTTTCATGTTTCGCCAGGCAAATGGCTATTACTGAAAGGT
TACTCTGGTGCGGGAAAAACCACACTGCTTAAAACATTATCCCACTGCTGGCCGTGGTTTAAAGGTGATATTTCTTCTCC
TGCTGACAGTTGGTATGTGTCACAAACACCGTTAATTAAAACCGGCTTACTGAAAGAGATTATTTGTAAAGCACTTCCTC
TGCCCGTAGACGATAAATCGTTGAGCGAAATACTGCATCAGGTTGGTCTGGGGAAATTGGCTGCGCGTATTCATGACCAC
GATCGCTGGGGAGATATTCTTTCCAGCGGCGAAAAACAACGTATCGCCCTGGCACGATTAATTTTACGACGTCCGAAATG
GATATTTCTTGACGAAACTACCTCTCATCTTGAGGAACAAGAGGCTATCCGCTTACTGCGTTTAGTGCGTGAAAAACTAC
CCACAAGCGGCGTCATTATGGTTACACATCAACCCGGTGTCTGGAACCTGGCCGATGATATTTGTGACATTAGCGCGGTT
TTATAA

Upstream 100 bases:

>100_bases
TATTCCTTTATATTTCATATTGTTAAATGATACTTAAATAAATTTCATCAGTAAATCATTGCCATAGATAATCATTGGAT
GGCACAATCAATTTTCGCTA

Downstream 100 bases:

>100_bases
AAACAATAAAAGCCCTGCTGTACGGAGATATAAATAAATGAAGCGAGTTCTTATTCCTGGCGTCATTTTATGTGGCGCTG
ATGTGGCGCAGGCCGTCGAT

Product: inner membrane ABC transporter ATP-binding protein

Products: NA

Alternate protein names: CDS102 [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MITIPITLRMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPA
LLGIFVLISVNKTWLIKLLTIRWREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
SLSMLITFTVILWQSAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQ
AELIALSNAESLQRQELSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFML
VSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTPDNKIILENLNFHVSPGKWLLLKG
YSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEILHQVGLGKLAARIHDH
DRWGDILSSGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAV
L

Sequences:

>Translated_561_residues
MITIPITLRMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPA
LLGIFVLISVNKTWLIKLLTIRWREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
SLSMLITFTVILWQSAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQ
AELIALSNAESLQRQELSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFML
VSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTPDNKIILENLNFHVSPGKWLLLKG
YSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEILHQVGLGKLAARIHDH
DRWGDILSSGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAV
L
>Mature_561_residues
MITIPITLRMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPA
LLGIFVLISVNKTWLIKLLTIRWREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
SLSMLITFTVILWQSAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQ
AELIALSNAESLQRQELSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFML
VSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTPDNKIILENLNFHVSPGKWLLLKG
YSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEILHQVGLGKLAARIHDH
DRWGDILSSGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAV
L

Specific function: Unknown

COG id: COG4178

COG function: function code R; ABC-type uncharacterized transport system, permease and ATPase components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI4826958, Length=523, Percent_Identity=25.0478011472275, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI9945308, Length=518, Percent_Identity=23.3590733590734, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4506341, Length=532, Percent_Identity=21.9924812030075, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI7262393, Length=555, Percent_Identity=23.2432432432432, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI73747915, Length=249, Percent_Identity=24.4979919678715, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI73747917, Length=249, Percent_Identity=24.4979919678715, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787772, Length=561, Percent_Identity=99.6434937611408, Blast_Score=1143, Evalue=0.0,
Organism=Escherichia coli, GI1786575, Length=333, Percent_Identity=26.1261261261261, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787112, Length=324, Percent_Identity=26.8518518518519, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786653, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000520, Length=542, Percent_Identity=26.9372693726937, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17564250, Length=537, Percent_Identity=26.6294227188082, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17532411, Length=599, Percent_Identity=25.2086811352254, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17532409, Length=505, Percent_Identity=23.960396039604, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI72000518, Length=565, Percent_Identity=24.7787610619469, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17542146, Length=522, Percent_Identity=21.6475095785441, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17558960, Length=184, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320339, Length=241, Percent_Identity=27.3858921161826, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323217, Length=247, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643394, Length=531, Percent_Identity=23.5404896421846, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24638550, Length=544, Percent_Identity=21.3235294117647, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638552, Length=544, Percent_Identity=21.3235294117647, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638554, Length=544, Percent_Identity=21.3235294117647, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638546, Length=544, Percent_Identity=21.3235294117647, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638556, Length=544, Percent_Identity=21.3235294117647, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638548, Length=544, Percent_Identity=21.3235294117647, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638558, Length=544, Percent_Identity=21.1397058823529, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010509
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF06472 ABC_membrane_2; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 64999; Mature: 64999

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIPITLRMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILGVVKIQVWLNDWNNDFF
CEEEHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCHHH
NALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIRWREWLTDYYLNRWFADKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQSLSMLITFTVILWQSAGTLS
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQ
EEECCEEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
AELIALSNAESLQRQELSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQ
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISGQINLGGLMKSRQAFMLVSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKP
HHCCCCCCCHHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KNCQHAVQVADASIRTPDNKIILENLNFHVSPGKWLLLKGYSGAGKTTLLKTLSHCWPWF
CHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCC
KGDISSPADSWYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEILHQVGLGKLAARIHDH
CCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHCC
DRWGDILSSGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIM
HHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VTHQPGVWNLADDICDISAVL
EEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MITIPITLRMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILGVVKIQVWLNDWNNDFF
CEEEHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCHHH
NALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIRWREWLTDYYLNRWFADKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQSLSMLITFTVILWQSAGTLS
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQ
EEECCEEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
AELIALSNAESLQRQELSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQ
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISGQINLGGLMKSRQAFMLVSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKP
HHCCCCCCCHHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KNCQHAVQVADASIRTPDNKIILENLNFHVSPGKWLLLKGYSGAGKTTLLKTLSHCWPWF
CHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCC
KGDISSPADSWYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEILHQVGLGKLAARIHDH
CCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHCC
DRWGDILSSGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIM
HHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VTHQPGVWNLADDICDISAVL
EEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]