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The map label for this gene is yncB [H]

Identifier: 157160928

GI number: 157160928

Start: 1539997

End: 1541034

Strand: Direct

Name: yncB [H]

Synonym: EcHS_A1535

Alternate gene names: 157160928

Gene position: 1539997-1541034 (Clockwise)

Preceding gene: 157160925

Following gene: 157160929

Centisome position: 33.16

GC content: 52.5

Gene sequence:

>1038_bases
ATGGGGCAACAAAAGCAGCGTAATCGACGTTGGGTTCTGGCCTCGCGTCCACATGGCGCACCGGTTCCGGAGAATTTCCG
TCTTGAAGAAGATGATGTCGCCACACCGGGTGAAGGACAGGTGTTACTGCGCACAGTTTATTTGTCCCTGGACCCGTATA
TGCGTGGACGTATGAGCGATGAGCCATCTTATTCACCGCCTGTTGATATTGGCGGCGTGATGGTCGGCGGCACGGTGAGC
CGTGTTGTGGAGTCGAATCATCCTGATTATCAGCCTGGCGACTGGGTGCTGGGCTACAGTGGATGGCAGGACTATGACAT
ATCCAGTGGTGATGATCTGGTGAAACTTGGCGATCATCCGCAAAATCCATCGTGGTCGCTGGGTGTGCTGGGGATGCCAG
GCTTTACCGCTTATATGGGGCTGCTGGATATCGGTCAGCCTAAAGAGGGCGAAACGTTGGTGGTAGCTGCGGCGACAGGT
CCTGTGGGAGCAACGGTGGGGCAAATCGGCAAACTTAAAGGTTGCAGGGTGGTGGGGGTTGCCGGTGGCGCGGAAAAATG
CCGCCATGCTATCGAGGTGCTGGGCTTCGATGTTTGTCTTGATCACCACGCGGATGATTTTGCCGAACAACTGGCGAAAG
CGTGCCCAAAAGGTATTGATATCTATTATGAAAACGTGGGCGGTAAGGTATTTGATGCAGTGCTACCATTACTTAATACA
TCTGCGCGCATTCCCGTTTGTGGCTTAGTGAGCAGCTATAACGCTACAGAGCTACCACCCGGTCCGGATCGTTTACCCCT
GTTGATGGCAACGGTGCTGAAAAAACGTATTCGCTTGCAAGGGTTTATTATCGCTCAGGATTATGGTCACCGCATCCATG
AGTTTCAGAAGGAGATGGGGCAATGGGTGAAAGAGGATAAAATCCACTACCGCGAAGATATTACTGATGGTTTAGAGAAT
GCGCCACAGACGTTTATCGGCCTGCTGAAGGGTAAAAACTTCGGCAAAGTGGTGATCCGCGTGGCGGGTGATGATTAA

Upstream 100 bases:

>100_bases
TTATTGCGTGTTGCAGAGGGGATGTGACGGCTGCAAACAAAACCAATCCCGTGAGCCTGCTACTATTGATGGATTCATGC
CAAAAGCACAGGAGAGCATT

Downstream 100 bases:

>100_bases
AGTTTCAACGGCGGCGTAAGCCGCCATAAAAATCCAGGCAAAAAGCTTATTTTCAGCTTTAATTAACTAACCACGTCATT
GTTCTGCTGCTAATAACAAC

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVS
RVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGVAGGAEKCRHAIEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHRIHEFQKEMGQWVKEDKIHYREDITDGLEN
APQTFIGLLKGKNFGKVVIRVAGDD

Sequences:

>Translated_345_residues
MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVS
RVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGVAGGAEKCRHAIEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHRIHEFQKEMGQWVKEDKIHYREDITDGLEN
APQTFIGLLKGKNFGKVVIRVAGDD
>Mature_344_residues
GQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSR
VVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGP
VGATVGQIGKLKGCRVVGVAGGAEKCRHAIEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNTS
ARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHRIHEFQKEMGQWVKEDKIHYREDITDGLENA
PQTFIGLLKGKNFGKVVIRVAGDD

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=338, Percent_Identity=38.1656804733728, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI226059133, Length=338, Percent_Identity=38.1656804733728, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI226246682, Length=350, Percent_Identity=37.7142857142857, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI226246680, Length=350, Percent_Identity=37.7142857142857, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI22748929, Length=350, Percent_Identity=37.7142857142857, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI226056130, Length=311, Percent_Identity=36.9774919614148, Blast_Score=188, Evalue=6e-48,
Organism=Homo sapiens, GI28557745, Length=341, Percent_Identity=28.4457478005865, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI194239674, Length=239, Percent_Identity=28.8702928870293, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI13236495, Length=239, Percent_Identity=28.8702928870293, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI226510941, Length=345, Percent_Identity=98.8405797101449, Blast_Score=701, Evalue=0.0,
Organism=Caenorhabditis elegans, GI133901710, Length=360, Percent_Identity=32.7777777777778, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI133901712, Length=360, Percent_Identity=32.7777777777778, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6323504, Length=372, Percent_Identity=27.4193548387097, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37590; Mature: 37459

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSD
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCHHHHCCCCC
EPSYSPPVDIGGVMVGGTVSRVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHP
CCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCC
QNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGV
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEE
AGGAEKCRHAIEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHRIHEFQKEMG
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHH
QWVKEDKIHYREDITDGLENAPQTFIGLLKGKNFGKVVIRVAGDD
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEEECCC
>Mature Secondary Structure 
GQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSD
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCHHHHCCCCC
EPSYSPPVDIGGVMVGGTVSRVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHP
CCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCC
QNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGV
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEE
AGGAEKCRHAIEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCC
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHRIHEFQKEMG
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHH
QWVKEDKIHYREDITDGLENAPQTFIGLLKGKNFGKVVIRVAGDD
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]