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The map label for this gene is btuR

Identifier: 157160775

GI number: 157160775

Start: 1374824

End: 1375414

Strand: Reverse

Name: btuR

Synonym: EcHS_A1379

Alternate gene names: 157160775

Gene position: 1375414-1374824 (Counterclockwise)

Preceding gene: 157160776

Following gene: 157160770

Centisome position: 29.62

GC content: 50.25

Gene sequence:

>591_bases
ATGAGTGATGAACGCTACCAACAGCGTCAGCAGCGAGTGAAAGAAAAAGTAGATGCTCGTGTGGCCCAGGCCCAGGATGA
ACGCGGTATTATCATCGTCTTTACCGGCAATGGAAAAGGCAAAACCACCGCGGCATTTGGTACGGCAACACGCGCAGTTG
GTCACGGAAAAAAAGTAGGCGTCGTGCAGTTTATTAAAGGCACCTGGCCTAATGGCGAACGCAATCTGCTGGAGCCACAT
GGCGTTGAGTTTCAGGTGATGGCAACGGGCTTTACCTGGGATACACAAAACCGCGAGTCTGATACCGCCGCCTGCCGCGA
AGTCTGGCAACATGCAAAGCGGATGCTTGCTGATTCCTCACTGGATATGGTTTTGCTTGATGAACTGACGTATATGGTGG
CGTATGACTATTTGCCACTGGAAGAAGTGGTGCAGGCGTTAAATGAACGTCCACATCAACAGACGGTGATTATCACGGGT
CGTGGTTGTCATCGGGATATTCTTGAACTGGCAGATACGGTAAGTGAATTACGCCCCGTCAAACATGCGTTTGATGCCGG
TGTAAAAGCGCAGATAGGGATCGATTATTAA

Upstream 100 bases:

>100_bases
ATATCATGCCGCTCTACCTCTGGCTGATGGGCGATGACAGCCGCCGTAAAACCGGCATGACCTTTGACGCCCAACCGGGC
CGTAAACCAGGAATTTCCCA

Downstream 100 bases:

>100_bases
TCTGTAAAAATGCCGGATATGACGTCCGGCATACTTTGATTAACCGTTATTATTACGTCCGCCAGAACGACGACCGCCGC
TCACCTGACTGTGACGTTTC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPH
GVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
RGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY

Sequences:

>Translated_196_residues
MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPH
GVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
RGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY
>Mature_195_residues
SDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHG
VEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITGR
GCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=100, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BTUR_ECOL6 (P0A9H6)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_753639.1
- ProteinModelPortal:   P0A9H6
- SMR:   P0A9H6
- PRIDE:   P0A9H6
- EnsemblBacteria:   EBESCT00000041644
- GeneID:   1035519
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c1735
- GeneTree:   EBGT00050000010959
- HOGENOM:   HBG286096
- OMA:   MTHVVLT
- ProtClustDB:   PRK05986
- BRENDA:   2.5.1.17
- GO:   GO:0005737
- InterPro:   IPR003724
- PIRSF:   PIRSF015617
- TIGRFAMs:   TIGR00708

Pfam domain/function: PF02572 CobA_CobO_BtuR

EC number: =2.5.1.17

Molecular weight: Translated: 21999; Mature: 21868

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVG
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCC
VVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSS
HHHHEECCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
LDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITGRGCHRDILELADTVSELRPV
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
KHAFDAGVKAQIGIDY
HHHHCCCCEEEEECCC
>Mature Secondary Structure 
SDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHCCCCCCC
VVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSS
HHHHEECCCCCCCCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
LDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITGRGCHRDILELADTVSELRPV
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHH
KHAFDAGVKAQIGIDY
HHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157