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The map label for this gene is hnr

Identifier: 157160741

GI number: 157160741

Start: 1338500

End: 1339513

Strand: Direct

Name: hnr

Synonym: EcHS_A1343

Alternate gene names: 157160741

Gene position: 1338500-1339513 (Clockwise)

Preceding gene: 157160740

Following gene: 157160742

Centisome position: 28.83

GC content: 48.62

Gene sequence:

>1014_bases
ATGACGCAGCCATTGGTCGGAAAACAGATTCTCATTGTTGAAGATGAGCAGGTATTTCGCTCGCTTCTGGATTCATGGTT
TTCCTCATTGGGAGCGACAACGGTACTGGCGGCTGATGGGGTGGATGCCCTTGAGTTGCTGGGAGGTTTCACTCCAGACC
TGATGATATGTGATATCGCGATGCCACGAATGAACGGGCTTAAACTGCTGGAGCATATACGTAACAGAGGCGACCAGACC
CCAGTTCTGGTGATATCTGCCACTGAAAATATGGCAGATATTGCCAAAGCGTTACGTCTGGGCGTTGAAGATGTTTTGCT
GAAACCAGTTAAAGATCTGAATCGCTTGCGCGAGATGGTTTTTGCCTGTCTCTATCCCAGCATGTTTAATTCGCGCGTTG
AGGAAGAGGAAAGGCTTTTTCGCGACTGGGATGCAATGGTTGATAACCCTGCCGCAGCGGCGAAATTATTACAGGAACTA
CAACCGCCGGTTCAGCAGGTGATTTCCCATTGCCGGGTTAATTATCGTCAATTGGTTGCCGCGGACAAACCCGGCCTGGT
GCTTGATATTGCCGCACTTTCGGAAAACGATCTGGCATTTTATTGCCTTGATGTCACCCGAGCTGGACATAATGGCGTAC
TTGCTGCCTTGTTATTACGCGCATTGTTTAACGGATTATTACAGGAACAGCTTGCACACCAAAATCAACGGTTGCCAGAG
TTGGGCGCGTTATTGAAGCAGGTAAACCATTTACTTCGTCAGGCCAATCTGCCGGGGCAGTTTCCGCTATTAGTTGGCTA
TTATCATCGCGAACTGAAAAATCTCATTCTGGTTTCTGCGGGTCTGAATGCGACGTTAAATACCGGCGAACACCAGGTGC
AAATCAGTAATGGTGTTCCGTTAGGCACTTTAGGTAACGCTTATTTGAATCAATTGAGCCAGCGATGCGATGCCTGGCAA
TGCCAAATATGGGGAACCGGTGGTCGACTGCGCTTGATGTTGTCTGCAGAATGA

Upstream 100 bases:

>100_bases
AACATTTGACCAGAATTTTTATCTACACTTAAGTTAATTCTGACAGGCGCAGGTGGCAATAGCATGCCACTATTGAGTAA
AGCCAGTCAGGGGAGAGAAC

Downstream 100 bases:

>100_bases
GCAAACGATAACGCGGGCTAAATTTGCATTACCTGCTAATGTCGGCTGGTGGTACTATCGTCGCCATTCGTATAAGTAAT
TGTCTTAATTATGCTAACTC

Product: response regulator of RpoS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQT
PVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPE
LGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQ
CQIWGTGGRLRLMLSAE

Sequences:

>Translated_337_residues
MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQT
PVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPE
LGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQ
CQIWGTGGRLRLMLSAE
>Mature_336_residues
TQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTP
VLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQELQ
PPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPEL
GALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQC
QIWGTGGRLRLMLSAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1787487, Length=337, Percent_Identity=100, Blast_Score=683, Evalue=0.0,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=37.5, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790299, Length=100, Percent_Identity=33, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=101, Percent_Identity=36.6336633663366, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HNR_ECO57 (P0AEV2)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A90846
- PIR:   H85703
- RefSeq:   NP_287480.1
- RefSeq:   NP_309764.1
- ProteinModelPortal:   P0AEV2
- SMR:   P0AEV2
- EnsemblBacteria:   EBESCT00000024582
- EnsemblBacteria:   EBESCT00000056975
- GeneID:   913115
- GeneID:   960487
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2011
- KEGG:   ecs:ECs1737
- GeneTree:   EBGT00050000008648
- HOGENOM:   HBG416104
- OMA:   NSDISSY
- ProtClustDB:   PRK10693
- BioCyc:   ECOL83334:ECS1737-MONOMER
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001789
- SMART:   SM00448

Pfam domain/function: PF00072 Response_reg; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 37303; Mature: 37172

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIA
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCEEEECC
MPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMV
CCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
FACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQELQPPVQQVISHCRVNYRQLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHH
ADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPE
CCCCCEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVP
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEECCCCEEEEECCCCC
LGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLMLSAE
CCCCCHHHHHHHHHHCCCEEEEEEECCCEEEEEEECC
>Mature Secondary Structure 
TQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIA
CCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCEEEECC
MPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMV
CCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
FACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQELQPPVQQVISHCRVNYRQLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHH
ADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPE
CCCCCEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVP
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEECCCCEEEEECCCCC
LGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLMLSAE
CCCCCHHHHHHHHHHCCCEEEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796