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The map label for this gene is mltE [H]

Identifier: 157160696

GI number: 157160696

Start: 1291505

End: 1292230

Strand: Direct

Name: mltE [H]

Synonym: EcHS_A1295

Alternate gene names: 157160696

Gene position: 1291505-1292230 (Clockwise)

Preceding gene: 157160693

Following gene: 157160698

Centisome position: 27.81

GC content: 50.96

Gene sequence:

>726_bases
GTGAAACAGAGACATGGCAATTCCTTGCTGACAACAGAAACGAAATGTATATCATGCCGCTTAGGTGTGCCGTTGTCACC
TCAACGGCGATTCCAGGCTATAAGGATAGAAGAAGTGAAATTGAGATGGTTTGCCTTTTTGATTGTGTTATTAGCGGGTT
GTTCATCAAAGCATGACTATACGAACCCGCCGTGGAACGCGAAAGTTCCGGTGCAACGTGCGATGCAGTGGATGCCAATA
AGCCAGAAAGCCGGTGCAGCCTGGGGCGTCGATCCACAATTGATCACGGCGATTATCGCTATCGAATCGGGTGGTAATCC
GAACGCGGTGAGTAAATCGAATGCCATTGGTTTGATGCAGTTAAAAGCTTCAACCTCCGGACGTGATGTTTATCGCCGTA
TGGGCTGGAGTGGTGAGCCGACGACCAGCGAGCTGAAAAATCCAGAGCGTAATATTTCAATGGGGGCGGCTTACCTGAAT
ATTCTGGAAACCGGCCCGCTGGCAGGCATTGAAGATCCGAAGGTACTGCAATATGCGCTGGTGGTGTCATACGCTAACGG
GGCAGGTGCGCTGCTACGGACTTTCTCGTCAGATCGGAAAAAGGCGATCAGCAAAATCAACGATTTGGATGCTGACGAGT
TCCTCGAACACGTAGCGCGAAATCACCCTGCGCCGCAGGCTCCGCGCTATATCTACAAACTTGAGCAGGCACTGGACGCG
ATGTAA

Upstream 100 bases:

>100_bases
TAACCTCGACGTTATTGACTTGATGCCCCGCGTCGGTAAGGCGCTGGATACCACGCAGCGCGGCGTGCTGTTTAATGCAG
TAACCCGATGGGGCAATTAA

Downstream 100 bases:

>100_bases
ATCAGTCGCGCACTTTGTCCGCTTTTTCCCGGGCTTCTCGCTCGAGAGAGAAAATAATCCGCTGTAATTGCCGCTCCACC
GTCGGGCTGACGTTAAGAAA

Product: membrane-bound lytic murein transglycosylase E

Products: NA

Alternate protein names: Peptidoglycan lytic endotransglycosylase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKQRHGNSLLTTETKCISCRLGVPLSPQRRFQAIRIEEVKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPI
SQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLN
ILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDA
M

Sequences:

>Translated_241_residues
MKQRHGNSLLTTETKCISCRLGVPLSPQRRFQAIRIEEVKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPI
SQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLN
ILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDA
M
>Mature_241_residues
MKQRHGNSLLTTETKCISCRLGVPLSPQRRFQAIRIEEVKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPI
SQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLN
ILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDA
M

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division (Potential) [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87081855, Length=203, Percent_Identity=99.5073891625616, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI87082191, Length=166, Percent_Identity=40.3614457831325, Blast_Score=137, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 26575; Mature: 26575

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRHGNSLLTTETKCISCRLGVPLSPQRRFQAIRIEEVKLRWFAFLIVLLAGCSSKHDY
CCCCCCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQ
CCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCEEEEE
LKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYAL
EECCCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDA
HEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
M
C
>Mature Secondary Structure
MKQRHGNSLLTTETKCISCRLGVPLSPQRRFQAIRIEEVKLRWFAFLIVLLAGCSSKHDY
CCCCCCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQ
CCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHEEEEEEEECCCCCCCCCCCCCEEEEE
LKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYAL
EECCCCHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDA
HEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
M
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12384590 [H]