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The map label for this gene is ybeM [H]

Identifier: 157160121

GI number: 157160121

Start: 694113

End: 694901

Strand: Direct

Name: ybeM [H]

Synonym: EcHS_A0677

Alternate gene names: 157160121

Gene position: 694113-694901 (Clockwise)

Preceding gene: 157160119

Following gene: 157160122

Centisome position: 14.95

GC content: 54.25

Gene sequence:

>789_bases
ATGCTGGTTGCCGCAGGACAGTTTGCTGTTACATCTGTGTGGGAAAAGAACGCTGAGATTTGTGCCTCGTTGATGGCGCA
GGCGGCGGAAAACGACGTATCGCTGTTCGTCCTGCCGGAAGCATTGCTGGCGCGCGATGATCATGATGCAGGTCTATCGG
TTAAATCAGCACAGCTGCTGGAAGGCGAATTCCTCGGACGTTTACGGCGAGAAAGTAAACGTAACATGATGACGACAATT
CTGACGATTCATGTTCCTTCAACGCCGGGGCGCGCATGGAATATGCTGGTGGCGCTACAGGCAGGAAACATCGTCGCCCG
TTATGCCAAATTGCATCTCTATGATGCATTTGCCATTCAGGAATCACGCCGTGTTGATGCTGGTAATGAAATCGCTCCGT
TACTCGAGGTGGAGGGGATGAAGGTCGGTCTGATGACCTGTTATGACTTACGCTTTCCAGAGCTGGCGCTGGCACAGGCA
TTACAGGGAGCTGAAATCCTGGTACTTCCTGCCGCCTGGGTTCGCGGGCCGCTCAAAGAGCATCACTGGTCAACGTTGCT
TGCCGCTCGTGCGCTGGATACCACCTGTTATATGGTGGCGGCGGGGGAGTGCGGGAACAAAAATATCGGTCAAAGCCGGA
TTATAGATCCCTTTGGAGTCACCATTGCGGCAGCGTCAGAAATGCCTGCACTCATTATGGCGGAAGTGACGCCCGAACGT
GTGCGTCAGGTGCGCGCGCAACTGCCCGTCTTAAACAACCGTCGCTTTGCGCCGCCGCAATTATTATGA

Upstream 100 bases:

>100_bases
TGTAACACTGCAAAATCCTGCTATTTGATTTGTATGAGTGATAAGTGTAACGCCGAATAATCGTCGTTGGCGAATTTTAC
GACTCTGACAGGAGGTGGCA

Downstream 100 bases:

>100_bases
TGTTTTTTTACTCGGCGCTTGATTCACCTTGTTACAGATTGCTATTGTGTGCGCGCGTCGAATGACCGTTAATATTCTCT
GGTTTTTAAGGCGCGTTCTG

Product: carbon-nitrogen family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDAGLSVKSAQLLEGEFLGRLRRESKRNMMTTI
LTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
VRQVRAQLPVLNNRRFAPPQLL

Sequences:

>Translated_262_residues
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDAGLSVKSAQLLEGEFLGRLRRESKRNMMTTI
LTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
VRQVRAQLPVLNNRRFAPPQLL
>Mature_262_residues
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDAGLSVKSAQLLEGEFLGRLRRESKRNMMTTI
LTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
VRQVRAQLPVLNNRRFAPPQLL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=279, Percent_Identity=35.4838709677419, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI297632348, Length=279, Percent_Identity=35.4838709677419, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI297632350, Length=279, Percent_Identity=35.4838709677419, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI9910460, Length=262, Percent_Identity=25.9541984732824, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI297632346, Length=202, Percent_Identity=33.1683168316832, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=272, Percent_Identity=29.7794117647059, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322335, Length=297, Percent_Identity=29.96632996633, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323383, Length=183, Percent_Identity=31.1475409836066, Blast_Score=96, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355835, Length=168, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17933642, Length=264, Percent_Identity=29.1666666666667, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28624; Mature: 28624

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDAGLSVKSAQLL
CEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCCCEECHHHHH
EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ
HHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE
HCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHCCCEEEEECHHHHCCCHHH
HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
HHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHH
VRQVRAQLPVLNNRRFAPPQLL
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDAGLSVKSAQLL
CEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCCCEECHHHHH
EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ
HHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE
HCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHCCCEEEEECHHHHCCCHHH
HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
HHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHH
VRQVRAQLPVLNNRRFAPPQLL
HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]