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The map label for this gene is allR [H]

Identifier: 157160029

GI number: 157160029

Start: 592588

End: 593403

Strand: Direct

Name: allR [H]

Synonym: EcHS_A0580

Alternate gene names: 157160029

Gene position: 592588-593403 (Clockwise)

Preceding gene: 157160028

Following gene: 157160030

Centisome position: 12.76

GC content: 52.57

Gene sequence:

>816_bases
ATGACGGAAGTTAGACGGCGCGGCAGGCCAGGACAGGCGGAGCCTGTGGCACAGAAGGGCGCACAGGCGTTAGAGCGGGG
AATTGCGATTCTGCAATATTTGGAAAAAAGTGGGGGAAGTTCGTCGGTTAGCGATATTTCTCTCAATCTGGATTTGCCGC
TCTCCACGACCTTTCGCTTGCTGAAGGTTTTACAGGCAGCGGATTTTGTCTATCAGGACAGTCAATTAGGCTGGTGGCAT
ATAGGATTAGGTGTCTTTAACGTCGGTGCGGCGTACATCCATAACCGCGATGTCCTCTCCGTCGCCGGGCCGTTTATGCG
CCGCCTGATGTTACTTTCCGGCGAAACGGTCAATGTCGCGATCCGTAACGGCAATGAAGCGGTATTAATTGGTCAGTTAG
AGTGTAAATCGATGGTCAGGATGTGTGCGCCACTGGGCAGTCGTCTGCCACTGCATGCTTCCGGTGCGGGCAAAGCGCTG
CTTTATCCGCTGGCGGAAGAGGAGTTGATGAGCATCATTCTGCAAACCGGTTTGCAGCAGTTTACGCCAACTACGCTTGT
GGATATGCCCACCTTGCTGAAGGACCTGGAACAAGCGCGTGAACTGGGCTATACCGTAGATAAAGAAGAGCATGTTGTAG
GTCTGAATTGCATAGCTTCAGCAATTTACGATGATGTCGGTAGTGTTGTTGCCGCTATCTCCATCTCCGGGCCTTCATCA
AGACTGACAGAAGATCGTTTTGTCAGTCAGGGTGAGCTGGTCAGAGACACCGCCCGCGATATCAGCACGGCGTTGGGACT
GAAAGCACATCCATAA

Upstream 100 bases:

>100_bases
AACAGGAACTCTGTTTTGCGTGACGCCTGCAACCGACTTGCATAAGATAAACTAATTGTTCATTGTTTATGCTCACTTGT
AGGTCGGAGTTAACGTAGGT

Downstream 100 bases:

>100_bases
TGTCTGTCGCATCCCGCTCTGCGGAGCGGGTTTTTTTGACAAAATTTGAAAGTTGGAAAAATTTTCCAATAAATAGAGGT
AGGAATAAAATGGCAAAAAT

Product: DNA-binding transcriptional repressor AllR

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWH
IGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSS
RLTEDRFVSQGELVRDTARDISTALGLKAHP

Sequences:

>Translated_271_residues
MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWH
IGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSS
RLTEDRFVSQGELVRDTARDISTALGLKAHP
>Mature_270_residues
TEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHI
GLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALL
YPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSR
LTEDRFVSQGELVRDTARDISTALGLKAHP

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=271, Percent_Identity=100, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI87082359, Length=264, Percent_Identity=42.4242424242424, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=30.6451612903226, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788131, Length=229, Percent_Identity=30.1310043668122, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789999, Length=251, Percent_Identity=29.8804780876494, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790752, Length=254, Percent_Identity=26.3779527559055, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788581, Length=248, Percent_Identity=28.2258064516129, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29270; Mature: 29139

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHH
LKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVA
HHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQTGLQQ
EECCCCEEEEECHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCHHHHHHHHHHHHHHH
FTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEECCCCCH
RLTEDRFVSQGELVRDTARDISTALGLKAHP
HCCHHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHH
LKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVAGPFMRRLMLLSGETVNVA
HHHHHHHHHHEECCCCCEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQTGLQQ
EECCCCEEEEECHHHHHHHHHHHCCCCCCCEECCCCCCEEEECCCHHHHHHHHHHHHHHH
FTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEECCCCCH
RLTEDRFVSQGELVRDTARDISTALGLKAHP
HCCHHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA