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The map label for this gene is ycgM [C]

Identifier: 157155625

GI number: 157155625

Start: 2414729

End: 2415430

Strand: Reverse

Name: ycgM [C]

Synonym: EcE24377A_2432

Alternate gene names: 157155625

Gene position: 2415430-2414729 (Counterclockwise)

Preceding gene: 157155116

Following gene: 157156465

Centisome position: 48.51

GC content: 55.41

Gene sequence:

>702_bases
ATGACTCAATACGTATTCGAACCACAAGCGCCCGTTACCGTACCGGTTGTTGGCAGTGATGAACAATTCCCCGTGCGCCG
CGTGTACTGCGTCGGACGTAACTATGCCGCCCACGCCCGCGAAATGGGCTTTGATCCGGATCGTGAACCGCCATTCTTCT
TCTGCAAACCGGCGGATGCCGTTGTTCCGGTTGCCGCTGGCGAAACGCTGGCGCTGCCGTATCCGGCGCAGACCGATAAC
TACCATTACGAAATTGAACTGGTGGTGGCGATTGGTAAAAAGGGCAGTGATATCCCGCTGGAAAACGCCCATGAATATGT
TTGGGGTTATGCCACGGGTCTTGATATGACTCGTCGTGACCGTCAAATGGAAATGCGCCAGATGGGCCGCCCGTGGGAAA
TCGGCAAAGCGTTTGATCTCTCGGCCCCCATCGCGCCGCTGCACAAAGCCAGCGAAACCGGCGGTATTGATAACGCGCCA
ATCTGGTTACAGGTTAACGGCGAAGATCATCAGCGCAGCGATATTCGCCATCTCATCTGGTCAGTGAATGAAACCATCAG
CTACCTGTCCGGCTTTTTTGAACTGCAACCGGGCGATCTGATCTTCACCGGTACGCCGGAAGGGGTTGGCCCGGTAGTGA
AAGGTGATGTGATCACCGGCAACGTCGAGGGCTTAACGCCTATCGCGGTGAAAATTGTCTGA

Upstream 100 bases:

>100_bases
GACCACGCAAGATACCGTGTTATTCAGTTTTTCGGACAGACCGGTACAAGAAGCCCTGGGACTGTTCCGCGAAGCGCGTT
ATTAATTTGGGAGAGAAAAA

Downstream 100 bases:

>100_bases
GGTGCATGATGAAGCTGTACAGTTTTTTTAATAGTTCAGCATCGTACCGGGTACGCATTGCGCTGGCGCTGAAAGGCATT
GATTACCAGACCGAAGGGGT

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTQYVFEPQAPVTVPVVGSDEQFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVVPVAAGETLALPYPAQTDN
YHYEIELVVAIGKKGSDIPLENAHEYVWGYATGLDMTRRDRQMEMRQMGRPWEIGKAFDLSAPIAPLHKASETGGIDNAP
IWLQVNGEDHQRSDIRHLIWSVNETISYLSGFFELQPGDLIFTGTPEGVGPVVKGDVITGNVEGLTPIAVKIV

Sequences:

>Translated_233_residues
MTQYVFEPQAPVTVPVVGSDEQFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVVPVAAGETLALPYPAQTDN
YHYEIELVVAIGKKGSDIPLENAHEYVWGYATGLDMTRRDRQMEMRQMGRPWEIGKAFDLSAPIAPLHKASETGGIDNAP
IWLQVNGEDHQRSDIRHLIWSVNETISYLSGFFELQPGDLIFTGTPEGVGPVVKGDVITGNVEGLTPIAVKIV
>Mature_232_residues
TQYVFEPQAPVTVPVVGSDEQFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVVPVAAGETLALPYPAQTDNY
HYEIELVVAIGKKGSDIPLENAHEYVWGYATGLDMTRRDRQMEMRQMGRPWEIGKAFDLSAPIAPLHKASETGGIDNAPI
WLQVNGEDHQRSDIRHLIWSVNETISYLSGFFELQPGDLIFTGTPEGVGPVVKGDVITGNVEGLTPIAVKIV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=40.0966183574879, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=40.1960784313725, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=41, Blast_Score=150, Evalue=6e-37,
Organism=Homo sapiens, GI156231349, Length=256, Percent_Identity=32.8125, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI40786394, Length=256, Percent_Identity=32.421875, Blast_Score=114, Evalue=6e-26,
Organism=Escherichia coli, GI1787428, Length=208, Percent_Identity=38.9423076923077, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17557057, Length=192, Percent_Identity=37.5, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=28.9592760180996, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=32.5358851674641, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=27.5229357798165, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25785; Mature: 25654

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYVFEPQAPVTVPVVGSDEQFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADA
CCCEEECCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
VVPVAAGETLALPYPAQTDNYHYEIELVVAIGKKGSDIPLENAHEYVWGYATGLDMTRRD
EEEEECCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHH
RQMEMRQMGRPWEIGKAFDLSAPIAPLHKASETGGIDNAPIWLQVNGEDHQRSDIRHLIW
HHHHHHHCCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
SVNETISYLSGFFELQPGDLIFTGTPEGVGPVVKGDVITGNVEGLTPIAVKIV
HHHHHHHHHHHEEEECCCCEEEECCCCCCCCEEECCEEECCCCCCCEEEEEEC
>Mature Secondary Structure 
TQYVFEPQAPVTVPVVGSDEQFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADA
CCEEECCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
VVPVAAGETLALPYPAQTDNYHYEIELVVAIGKKGSDIPLENAHEYVWGYATGLDMTRRD
EEEEECCCEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHH
RQMEMRQMGRPWEIGKAFDLSAPIAPLHKASETGGIDNAPIWLQVNGEDHQRSDIRHLIW
HHHHHHHCCCCCCCCCEEECCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
SVNETISYLSGFFELQPGDLIFTGTPEGVGPVVKGDVITGNVEGLTPIAVKIV
HHHHHHHHHHHEEEECCCCEEEECCCCCCCCEEECCEEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]