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The map label for this gene is pocR [H]

Identifier: 157155157

GI number: 157155157

Start: 2244644

End: 2245558

Strand: Reverse

Name: pocR [H]

Synonym: EcE24377A_2277

Alternate gene names: 157155157

Gene position: 2245558-2244644 (Counterclockwise)

Preceding gene: 157155813

Following gene: 157156911

Centisome position: 45.09

GC content: 44.59

Gene sequence:

>915_bases
ATGATTTCTGCGGCGACACTTAATTCAGAACTCATTAATAAAATCGCGCAGGATTTTGCGAAGGCGACCAGCCTTGCGGT
TGTCGTGGTCAATATTCACGGCGATGAAATTTCCGAGCTGTTTAACTTCACTCCATTTTGTCAGATGATGCGGCAACACC
CTCAGCTAAGCACTCGATGTCGCATGAGCGATCGTTGTGGGGGCCTGGAAGCCTCTAAATCCGATCAGCCTTGTATTTAT
CGCTGTCATGCCGGATTAACCGATTTCTCTATTCCACTGGTAATCGCCGGACATTTAGTCGGTTTTGTATTGTGCGGGCA
AGTTCGTCTGCGTAATGATGATGTCGATTTGGTCGATATTCTGAATGTCGATGATTGCTGGCAGGCAGATCCCGAATTAC
TTAATGAATTCCGCAAAGTTCCTGAGATGGATTACTCAAGAGTTATGGCCTCTGCTGATTTGTTGAAGTTGATTGTGGAA
AATTGCCTCAAAAAACAACTCAATTTTGTGGTTATTAAAGAGAACAAATCTCGGTCAGATTCGGTGCGCCAGACTCGTGC
GCCTAATCCCCACGACAATAAAATGAAAAAAGCTTTACGCTATATTGATGCGCATTTATCAGACGATTTGCGTCTGGAAG
ATGTCGCCTCGCACGTTTATCTAAGTCCTTATTATTTCAGTAAGTTATTCAAGAAATACCATGGAATCGGTTTTAATGCG
TGGGTAAACCAACAACGGATGGCCAGCGCTCGTGAGTTACTGTGCCATAGTGACTGGAGCATCGCCAGCATTGCGCGTAA
TTTAGGTTTTTCGCAAACCAGTTATTTTTGCAAAGTTTTCCGTCAGACTTATCAGGTTACGCCGCAGGTGTATCGACAGC
AAGTGAGTGAAAATGCGGCGATGGAAACGGTATAG

Upstream 100 bases:

>100_bases
TCCTTTGTGCTTCTCGTCAGTAAATCATCAGGGATGATGTGAAGATTAAATGTAAAACAATTGTTTTGCTATAACAATAA
ATTAACTGGGAGGTTTTATC

Downstream 100 bases:

>100_bases
AATAAATGCTAAAAAAAGGGAAGGTTTAAATAAACGCTGGAATGAATAATTAACGTTATTTACGTGTTATGGGAAAAGTG
AAATCAGCTCATAACATACG

Product: regulatory protein PocR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MISAATLNSELINKIAQDFAKATSLAVVVVNIHGDEISELFNFTPFCQMMRQHPQLSTRCRMSDRCGGLEASKSDQPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDDVDLVDILNVDDCWQADPELLNEFRKVPEMDYSRVMASADLLKLIVE
NCLKKQLNFVVIKENKSRSDSVRQTRAPNPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYHGIGFNA
WVNQQRMASARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQVYRQQVSENAAMETV

Sequences:

>Translated_304_residues
MISAATLNSELINKIAQDFAKATSLAVVVVNIHGDEISELFNFTPFCQMMRQHPQLSTRCRMSDRCGGLEASKSDQPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDDVDLVDILNVDDCWQADPELLNEFRKVPEMDYSRVMASADLLKLIVE
NCLKKQLNFVVIKENKSRSDSVRQTRAPNPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYHGIGFNA
WVNQQRMASARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQVYRQQVSENAAMETV
>Mature_304_residues
MISAATLNSELINKIAQDFAKATSLAVVVVNIHGDEISELFNFTPFCQMMRQHPQLSTRCRMSDRCGGLEASKSDQPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDDVDLVDILNVDDCWQADPELLNEFRKVPEMDYSRVMASADLLKLIVE
NCLKKQLNFVVIKENKSRSDSVRQTRAPNPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYHGIGFNA
WVNQQRMASARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQVYRQQVSENAAMETV

Specific function: Positive regulatory protein of pdu and cob operons [H]

COG id: COG4936

COG function: function code TK; Predicted sensor domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786251, Length=121, Percent_Identity=34.7107438016529, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790391, Length=99, Percent_Identity=39.3939393939394, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR018771 [H]

Pfam domain/function: PF10114 Hist_Kin_Sens; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34655; Mature: 34655

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAATLNSELINKIAQDFAKATSLAVVVVNIHGDEISELFNFTPFCQMMRQHPQLSTRC
CCCCHHCCHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHH
RMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDDVDLVDI
CCHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEEE
LNVDDCWQADPELLNEFRKVPEMDYSRVMASADLLKLIVENCLKKQLNFVVIKENKSRSD
CCCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCH
SVRQTRAPNPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYHGIGFNA
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
WVNQQRMASARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQVYRQQVSENAA
HHCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
METV
CCCC
>Mature Secondary Structure
MISAATLNSELINKIAQDFAKATSLAVVVVNIHGDEISELFNFTPFCQMMRQHPQLSTRC
CCCCHHCCHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHH
RMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDDVDLVDI
CCHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCEEEE
LNVDDCWQADPELLNEFRKVPEMDYSRVMASADLLKLIVENCLKKQLNFVVIKENKSRSD
CCCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCH
SVRQTRAPNPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYHGIGFNA
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
WVNQQRMASARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQVYRQQVSENAA
HHCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
METV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8071226; 9352910; 11677609; 8501034 [H]