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The map label for this gene is gcp

Identifier: 156937061

GI number: 156937061

Start: 229405

End: 230394

Strand: Reverse

Name: gcp

Synonym: Igni_0266

Alternate gene names: 156937061

Gene position: 230394-229405 (Counterclockwise)

Preceding gene: 156937062

Following gene: 156937060

Centisome position: 17.76

GC content: 62.42

Gene sequence:

>990_bases
TTGTACGTCCTCGGCATAGAGAGCACCGCCCACACCATAGGGGTGGGAATAGTTAACGAGAGGGCAGAGGTGCTGGCGAA
CGAGATGCACACCTACGTGCCGAAGGAAGGCGGGATCCACCCGAGGGAGGCCGCGAGGCACCACGCGGAGTGGGGGCCGA
GGCTCGTAAAGAGGGCCTTGGAGGTGGCGGGGCTAAGGCCGGAGGACTTGGACGCGGTGGCCTACAGCGCGGGCCCCGGG
CTGGGGCCTTGTTTGAGGACGGGAGCCGTCATGGCGCGGGCCCTCGCCGCCTTCTACGAAAAGCCCCTAGTGCCGGTCAA
CCACTCGTTGGCTCACATAGAGATAGCTAGGGCCGTGACCGGCTTCTCTAAACCCGTAGCGATTTACGTATCCGGGGGAA
GCACGATAATTTCTGCCCCAGCGATAAAGAGGTACAGGGTGTACGGGGAGACCTTAGACATAGGTTTGGGCAACTTGTTA
GACACCTTCGCCAGGGAGGTGGGGATAGGGCCCCCCTTCGTCAAGGGAGGGGTACACGTGGTGGAGCTCTGCTCCGAAGG
GGCGGAAGAGCCGGCGGACCTCCCCTACACAGTCCAAGGGGTGGACCTCTCCTTCTCGGGCCTCTTAACGGCAGCCCTGA
GGGCGTGGAAGAAGGAGGACAAGAAGAAGGTATGCTACGGCCTCTGGGAAACCGCTTACGACATGGTGGTGGAAGTGGGC
GAGAGGGCGTTGGCCCACTCCAAGCTAAAGGAGGTGGTCCTAGTGGGGGGCGTGGCGGGCTCGAAGAGGCTCCAGCGGAA
GGTGGCGCTCATGAGCGAGGAGAGGGGCGTCTCCTTCAAGCCCATACCTTACGAGCTAGCGAGGGACAACGGCGCCATGA
TCGCTTGGACCGGCTTGCTCTACTACAAGCACGGCTTCACCGTCGCTCCCGAGGAGGCGTTCGTGAGGCAGAGGTGGAGG
CTGGACGAGGTAGAAGTTCCGTGGCTTTAA

Upstream 100 bases:

>100_bases
ACTTCCTCTGCTGACCTCGTCATCAAGATGTTGAAGAGCAAGCTCCTAGGGGACGAGGAGTGCTTATTCGAGGTCCGGGC
CAAGTGACCCGGAGGACGCC

Downstream 100 bases:

>100_bases
ATACGCCCGACCCCTAAAGGGCTCCCGGTATAAGCTCTTGAAACCGATCAACGAGATTGTCAAAAAGTGGTTCGAGCTCA
ACCCTCACTACGCCTCGGCG

Product: metalloendopeptidase glycoprotease family

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MYVLGIESTAHTIGVGIVNERAEVLANEMHTYVPKEGGIHPREAARHHAEWGPRLVKRALEVAGLRPEDLDAVAYSAGPG
LGPCLRTGAVMARALAAFYEKPLVPVNHSLAHIEIARAVTGFSKPVAIYVSGGSTIISAPAIKRYRVYGETLDIGLGNLL
DTFAREVGIGPPFVKGGVHVVELCSEGAEEPADLPYTVQGVDLSFSGLLTAALRAWKKEDKKKVCYGLWETAYDMVVEVG
ERALAHSKLKEVVLVGGVAGSKRLQRKVALMSEERGVSFKPIPYELARDNGAMIAWTGLLYYKHGFTVAPEEAFVRQRWR
LDEVEVPWL

Sequences:

>Translated_329_residues
MYVLGIESTAHTIGVGIVNERAEVLANEMHTYVPKEGGIHPREAARHHAEWGPRLVKRALEVAGLRPEDLDAVAYSAGPG
LGPCLRTGAVMARALAAFYEKPLVPVNHSLAHIEIARAVTGFSKPVAIYVSGGSTIISAPAIKRYRVYGETLDIGLGNLL
DTFAREVGIGPPFVKGGVHVVELCSEGAEEPADLPYTVQGVDLSFSGLLTAALRAWKKEDKKKVCYGLWETAYDMVVEVG
ERALAHSKLKEVVLVGGVAGSKRLQRKVALMSEERGVSFKPIPYELARDNGAMIAWTGLLYYKHGFTVAPEEAFVRQRWR
LDEVEVPWL
>Mature_329_residues
MYVLGIESTAHTIGVGIVNERAEVLANEMHTYVPKEGGIHPREAARHHAEWGPRLVKRALEVAGLRPEDLDAVAYSAGPG
LGPCLRTGAVMARALAAFYEKPLVPVNHSLAHIEIARAVTGFSKPVAIYVSGGSTIISAPAIKRYRVYGETLDIGLGNLL
DTFAREVGIGPPFVKGGVHVVELCSEGAEEPADLPYTVQGVDLSFSGLLTAALRAWKKEDKKKVCYGLWETAYDMVVEVG
ERALAHSKLKEVVLVGGVAGSKRLQRKVALMSEERGVSFKPIPYELARDNGAMIAWTGLLYYKHGFTVAPEEAFVRQRWR
LDEVEVPWL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI8923380, Length=333, Percent_Identity=41.7417417417417, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI116812636, Length=339, Percent_Identity=27.4336283185841, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=34.2105263157895, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71995670, Length=335, Percent_Identity=39.7014925373134, Blast_Score=240, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI17557464, Length=326, Percent_Identity=30.9815950920245, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322891, Length=367, Percent_Identity=38.4196185286104, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320099, Length=365, Percent_Identity=27.1232876712329, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI21357207, Length=343, Percent_Identity=40.5247813411079, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI20129063, Length=367, Percent_Identity=27.7929155313352, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_IGNH4 (A8A948)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001434857.1
- ProteinModelPortal:   A8A948
- SMR:   A8A948
- STRING:   A8A948
- MEROPS:   M22.003
- GeneID:   5561741
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0266
- eggNOG:   arNOG04080
- HOGENOM:   HBG304663
- OMA:   TQRFRTD
- BioCyc:   IHOS453591:IGNI_0266-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01446
- InterPro:   IPR022449
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03722
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35851; Mature: 35851

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVLGIESTAHTIGVGIVNERAEVLANEMHTYVPKEGGIHPREAARHHAEWGPRLVKRAL
CEEEEECCCCHHEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHH
EVAGLRPEDLDAVAYSAGPGLGPCLRTGAVMARALAAFYEKPLVPVNHSLAHIEIARAVT
HHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GFSKPVAIYVSGGSTIISAPAIKRYRVYGETLDIGLGNLLDTFAREVGIGPPFVKGGVHV
CCCCCEEEEEECCCEEEECCCHHHHHEECCHHHCCHHHHHHHHHHHHCCCCCCHHCCHHH
VELCSEGAEEPADLPYTVQGVDLSFSGLLTAALRAWKKEDKKKVCYGLWETAYDMVVEVG
HHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERALAHSKLKEVVLVGGVAGSKRLQRKVALMSEERGVSFKPIPYELARDNGAMIAWTGLL
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEEE
YYKHGFTVAPEEAFVRQRWRLDEVEVPWL
EEECCCEECCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MYVLGIESTAHTIGVGIVNERAEVLANEMHTYVPKEGGIHPREAARHHAEWGPRLVKRAL
CEEEEECCCCHHEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHH
EVAGLRPEDLDAVAYSAGPGLGPCLRTGAVMARALAAFYEKPLVPVNHSLAHIEIARAVT
HHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GFSKPVAIYVSGGSTIISAPAIKRYRVYGETLDIGLGNLLDTFAREVGIGPPFVKGGVHV
CCCCCEEEEEECCCEEEECCCHHHHHEECCHHHCCHHHHHHHHHHHHCCCCCCHHCCHHH
VELCSEGAEEPADLPYTVQGVDLSFSGLLTAALRAWKKEDKKKVCYGLWETAYDMVVEVG
HHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERALAHSKLKEVVLVGGVAGSKRLQRKVALMSEERGVSFKPIPYELARDNGAMIAWTGLL
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEEEE
YYKHGFTVAPEEAFVRQRWRLDEVEVPWL
EEECCCEECCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA