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The map label for this gene is 156937006

Identifier: 156937006

GI number: 156937006

Start: 187120

End: 187839

Strand: Reverse

Name: 156937006

Synonym: Igni_0211

Alternate gene names: NA

Gene position: 187839-187120 (Counterclockwise)

Preceding gene: 156937008

Following gene: 156937005

Centisome position: 14.48

GC content: 48.19

Gene sequence:

>720_bases
GTGAACAAGCAGAGCAATGAGGTACAAAGAAAGATAGTGATGCCCGGGGACTTAGTAGTGAAGGGCAACTATACTATCAA
CCCAAAGTCAATAATGTACTTGTACAAGGTGGGAGACGCGGTTTACGCGGCAGTGGCGGGGATGGCAGAAATAACGAACG
GTACTGTTTCCCTCATCCCGTTTGAGGGAACTTACATTCCTAAGCCGGGAGACTTAGTAATAGGGGTAGTGGAAAACTTC
GTAGTGACCCACTGGCAAGTGGACATAAACTCGCCCTACATAGGCATACTTCACGTCAGCAACCTCCTGGGGAGGCCCTA
CAACCCTGCTAAGGACAATTTGAAAGAATACTTAGATATAGGAGACTATATCATAGCCAAGGTAGAATCATTCGACAGGA
CTAAAGACCCGATACTGAACGTGCAAGGTAAGGGATTGGGGAGGGTCGTAGAGGGCAAGATAGTAGAAATAAAGCCGTCA
AGAGTGCCTAGGGTAATAGGAAAGAAGAAGAGTATGTTGAACGTCATAAAGGGAGACACCGGCTGCGAAATCATAGTGGG
CGCCAACGGCAGGATATGGATCAAGTGTCCCAACAAAGACCTCGAGGACATAGTAACGCTGGCAATAAAGCTAATAGAGA
GGGAGGCCTTCGCTACCGGCCTAACTGAGAAGGTCAGAGTTCTTATCGCCACCGAAAAGCACGAGAGGGGACTGCTATGA

Upstream 100 bases:

>100_bases
TATAAAGTCGCTCGATGTACGTAATCTGCCCAGCTATTACCTTTAGGCTCATGCAACCACCATATTTAGCTCCGCCGCAT
CTCCCCTATGGGGTTAAAGG

Downstream 100 bases:

>100_bases
TGAAGGAGCCTCCCGTGCCGCTAATAGTGGACGGTAAGCGCCACGACGGAAGGGGGCCGGCTGACCTCAGGCCCTTAGAG
ATGAAGGTCGGCGTGCTATA

Product: exosome complex RNA-binding protein Rrp4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNKQSNEVQRKIVMPGDLVVKGNYTINPKSIMYLYKVGDAVYAAVAGMAEITNGTVSLIPFEGTYIPKPGDLVIGVVENF
VVTHWQVDINSPYIGILHVSNLLGRPYNPAKDNLKEYLDIGDYIIAKVESFDRTKDPILNVQGKGLGRVVEGKIVEIKPS
RVPRVIGKKKSMLNVIKGDTGCEIIVGANGRIWIKCPNKDLEDIVTLAIKLIEREAFATGLTEKVRVLIATEKHERGLL

Sequences:

>Translated_239_residues
MNKQSNEVQRKIVMPGDLVVKGNYTINPKSIMYLYKVGDAVYAAVAGMAEITNGTVSLIPFEGTYIPKPGDLVIGVVENF
VVTHWQVDINSPYIGILHVSNLLGRPYNPAKDNLKEYLDIGDYIIAKVESFDRTKDPILNVQGKGLGRVVEGKIVEIKPS
RVPRVIGKKKSMLNVIKGDTGCEIIVGANGRIWIKCPNKDLEDIVTLAIKLIEREAFATGLTEKVRVLIATEKHERGLL
>Mature_239_residues
MNKQSNEVQRKIVMPGDLVVKGNYTINPKSIMYLYKVGDAVYAAVAGMAEITNGTVSLIPFEGTYIPKPGDLVIGVVENF
VVTHWQVDINSPYIGILHVSNLLGRPYNPAKDNLKEYLDIGDYIIAKVESFDRTKDPILNVQGKGLGRVVEGKIVEIKPS
RVPRVIGKKKSMLNVIKGDTGCEIIVGANGRIWIKCPNKDLEDIVTLAIKLIEREAFATGLTEKVRVLIATEKHERGLL

Specific function: Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome (Potential) [H]

COG id: COG1097

COG function: function code J; RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321860, Length=196, Percent_Identity=24.4897959183673, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24762324, Length=165, Percent_Identity=29.0909090909091, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR018111
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967 [H]

Pfam domain/function: PF00013 KH_1; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 26382; Mature: 26382

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQSNEVQRKIVMPGDLVVKGNYTINPKSIMYLYKVGDAVYAAVAGMAEITNGTVSLIP
CCCCCCHHHHEEECCCCEEEECCEEECHHHEEEEEECCHHHHHHHHHHHHHCCCEEEEEE
FEGTYIPKPGDLVIGVVENFVVTHWQVDINSPYIGILHVSNLLGRPYNPAKDNLKEYLDI
ECCEECCCCCCEEEEEHHCEEEEEEEEECCCCEEEEEEEHHHHCCCCCCHHHHHHHHHCC
GDYIIAKVESFDRTKDPILNVQGKGLGRVVEGKIVEIKPSRVPRVIGKKKSMLNVIKGDT
CHHHHHHHHHCCCCCCCEEEECCCCCCEEECCEEEEECCCCCCHHHCCHHHHHHHHCCCC
GCEIIVGANGRIWIKCPNKDLEDIVTLAIKLIEREAFATGLTEKVRVLIATEKHERGLL
CCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MNKQSNEVQRKIVMPGDLVVKGNYTINPKSIMYLYKVGDAVYAAVAGMAEITNGTVSLIP
CCCCCCHHHHEEECCCCEEEECCEEECHHHEEEEEECCHHHHHHHHHHHHHCCCEEEEEE
FEGTYIPKPGDLVIGVVENFVVTHWQVDINSPYIGILHVSNLLGRPYNPAKDNLKEYLDI
ECCEECCCCCCEEEEEHHCEEEEEEEEECCCCEEEEEEEHHHHCCCCCCHHHHHHHHHCC
GDYIIAKVESFDRTKDPILNVQGKGLGRVVEGKIVEIKPSRVPRVIGKKKSMLNVIKGDT
CHHHHHHHHHCCCCCCCEEEECCCCCCEEECCEEEEECCCCCCHHHCCHHHHHHHHCCCC
GCEIIVGANGRIWIKCPNKDLEDIVTLAIKLIEREAFATGLTEKVRVLIATEKHERGLL
CCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]