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The map label for this gene is cinA

Identifier: 15675867

GI number: 15675867

Start: 1767642

End: 1768913

Strand: Reverse

Name: cinA

Synonym: SPy_2117

Alternate gene names: 15675867

Gene position: 1768913-1767642 (Counterclockwise)

Preceding gene: 15675868

Following gene: 15675866

Centisome position: 95.49

GC content: 41.43

Gene sequence:

>1272_bases
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTAACTTGGTAATTTTATGTGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACGGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Upstream 100 bases:

>100_bases
AAGAGGCTTGTGTTTTCAATAGAATCTTCTAATTCTTCGTGAATTGGAAGATTTTTTGATAAAATGAGATCAGATTACGA
ATAGATAAGTAGGTGGGGAA

Downstream 100 bases:

>100_bases
TGTTATTTAGTAGCTATAGTAGGATATGGTTTACAATTATGTAGATTAATCCTGCTGACGATGGTTTGTTAAAAAAGAGG
AGAAAGTATTGGCAAAAAAA

Product: competence damage-inducible protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Sequences:

>Translated_423_residues
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL
>Mature_423_residues
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSNLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=296, Percent_Identity=29.7297297297297, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789052, Length=157, Percent_Identity=38.2165605095541, Blast_Score=83, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323832, Length=181, Percent_Identity=25.9668508287293, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINA_STRP1 (Q99XP1)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_270041.1
- RefSeq:   YP_283163.1
- ProteinModelPortal:   Q99XP1
- SMR:   Q99XP1
- EnsemblBacteria:   EBSTRT00000001492
- EnsemblBacteria:   EBSTRT00000028624
- GeneID:   3571087
- GeneID:   901756
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_2117
- KEGG:   spz:M5005_Spy_1800
- GeneTree:   EBGT00050000027891
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   PRK00549
- BioCyc:   SPYO160490:SPY2117-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1800-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 45990; Mature: 45990

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRS
CCCEEEEECHHHHCCEEECCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCC
NLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQ
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCE
VIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPMVNEELVPLLSKQYSTLYSKV
EEECCCCCCCCCCEEECCEEEECCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHHHH
LRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPG
HHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
ASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTG
HHHHHCCCEEEEEHHHHHHHHCCCHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEC
VAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDVRYIATLHAFNMVRKTLLKLE
CCCCCHHHCCCCCEEEEEECCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
NLL
HCC
>Mature Secondary Structure
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRS
CCCEEEEECHHHHCCEEECCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCC
NLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQ
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCE
VIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPMVNEELVPLLSKQYSTLYSKV
EEECCCCCCCCCCEEECCEEEECCEEEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHHHH
LRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPG
HHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
ASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTG
HHHHHCCCEEEEEHHHHHHHHCCCHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEC
VAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDVRYIATLHAFNMVRKTLLKLE
CCCCCHHHCCCCCEEEEEECCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
NLL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296