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The map label for this gene is hutG

Identifier: 15675847

GI number: 15675847

Start: 1742066

End: 1743052

Strand: Direct

Name: hutG

Synonym: SPy_2090

Alternate gene names: 15675847

Gene position: 1742066-1743052 (Clockwise)

Preceding gene: 15675846

Following gene: 15675849

Centisome position: 94.04

GC content: 45.59

Gene sequence:

>987_bases
ATGCTAGAAGATTACTACCCATCCACCACTAGCTATTATCATGGTGGGATCGACGATGACTTATATACTGCCAAATGGGG
CATGGTCATGACTTTCCTTGACCTTAACGACAGCTCACTAACCCCATTTGAAGGGACACATTTTGCCTTGATTGGCTTTA
AAAGTGATAAGGGGGTTTATATCAATAATGGTCGTGTCGGAGCGGTCGAAAGTCCAGCTGCCATACGAACCCAGCTCGCC
AAATTCCCTTGGCATTTAGGAAACCAAGTTATGGTTTACGATGTGGGTAACATTGACGGCCCCAATCGCTCTTTGGAACA
ACTGCAAAACAGTTTAAGCAAAGCCATCAAACGGATGTGTGACCTCAATCTCAAACCCATCGTCTTAGGAGGTGGCCATG
AAACCGCCTACGGCCACTACTTAGGCCTACGCCAAAGCCTATCCCCAAGTGATGACCTAGCTGTCATCAATATGGACGCC
CACTTTGATTTAAGGCCTTACGACCAAACAGGCCCTAATTCAGGGACAGGCTTTCGACAGATGTTTGACGATGCGGTTGC
TGACAAACGCCTCTTTAAATACTTCGTTTTAGGCATTCAAGAACATAATAACAACCTTTTCCTATTTGACTTTGTGGCAA
AATCCAAGGGCATTCAATTTTTAACAGGTCAAGACATCTACCAAATGGGCCATCAAAAGGTCTGCCGAGCCATTGACCGT
TTCTTAGAAGGGCAAGAAAGGGTCTACCTGACCATTGACATGGATTGTTTCTCAGTTGGTGCTGCGCCTGGGGTTAGTGC
TATCCAGTCCCTCGGTGTTGACCCAAATCTTGCCGTCTTAGTTTTGCAACACATTGCAGCTAGCGGAAAATTAGTTGGCT
TTGATGTGGTTGAGGTTTCACCACCACACGATATTGATAACCACACCGCCAATTTAGCAGCCACCTTTATCTTTTACCTC
GTACAGATTATGGCACAACATAGCTAA

Upstream 100 bases:

>100_bases
TTTTATTGCTCTGCTATTCCTAAAAACCAGTGACAAAGGCCAAGAAAGTGTTGACTGTAAGTTTTATTTTGCTATCATAA
TCCTAAAGGAGATGACGCGC

Downstream 100 bases:

>100_bases
AACCCTCTGATTCACTTCAGAGGGTTTTCCTTAGCTTTTAGCAGATAATTGTTGACGCAAATCGTTCAACTCACTCACCA
AATGACAATCTCGGTAAGGG

Product: formimidoylglutamase

Products: NA

Alternate protein names: Formiminoglutamase; Formiminoglutamate hydrolase

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLA
KFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDR
FLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYL
VQIMAQHS

Sequences:

>Translated_328_residues
MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLA
KFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDR
FLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYL
VQIMAQHS
>Mature_328_residues
MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLA
KFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDR
FLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYL
VQIMAQHS

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family

Homologues:

Organism=Homo sapiens, GI37537722, Length=300, Percent_Identity=24.6666666666667, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTG_STRP1 (Q99XQ9)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_270021.1
- RefSeq:   YP_283141.1
- ProteinModelPortal:   Q99XQ9
- EnsemblBacteria:   EBSTRT00000001596
- EnsemblBacteria:   EBSTRT00000027745
- GeneID:   3571104
- GeneID:   901730
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_2090
- KEGG:   spz:M5005_Spy_1778
- GeneTree:   EBGT00050000028626
- HOGENOM:   HBG289964
- OMA:   GILNLDA
- ProtClustDB:   PRK13775
- BioCyc:   SPYO160490:SPY2090-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1778-MONOMER
- HAMAP:   MF_00737
- InterPro:   IPR005923
- InterPro:   IPR006035
- Gene3D:   G3DSA:3.40.800.10
- PANTHER:   PTHR11358
- PRINTS:   PR00116

Pfam domain/function: PF00491 Arginase

EC number: =3.5.3.8

Molecular weight: Translated: 36327; Mature: 36327

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS01053 ARGINASE_1; PS51409 ARGINASE_2; PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVY
CCCCCCCCCCCEECCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCEE
INNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMC
EECCEECCCCCCHHHHHHHHHCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
DLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDAHFDLRPYDQTGPNSGTGFRQ
CCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHH
MFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDR
HHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHH
FLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASGKLVGFDVVEVS
HHCCCCEEEEEEECHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEEC
PPHDIDNHTANLAATFIFYLVQIMAQHS
CCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVY
CCCCCCCCCCCEECCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCEEEEEEEECCCCEE
INNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMC
EECCEECCCCCCHHHHHHHHHCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
DLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDAHFDLRPYDQTGPNSGTGFRQ
CCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHH
MFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDR
HHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHH
FLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASGKLVGFDVVEVS
HHCCCCEEEEEEECHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEEEC
PPHDIDNHTANLAATFIFYLVQIMAQHS
CCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296