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The map label for this gene is scrR [H]

Identifier: 15675647

GI number: 15675647

Start: 1509476

End: 1510441

Strand: Direct

Name: scrR [H]

Synonym: SPy_1817

Alternate gene names: 15675647

Gene position: 1509476-1510441 (Clockwise)

Preceding gene: 15675646

Following gene: 15675654

Centisome position: 81.49

GC content: 38.51

Gene sequence:

>966_bases
GTGGTCGCAAAATTAACAGACGTGGCAGCCTTGGCGGGTGTCAGTCCAACAACTGTTTCGCGAGTAATCAACAAAAAAGG
CTACCTTTCCCAAAAAACAGTGAATAAGGTGAATAAGGCCATGCGTGAATTGGGCTACAAGCCTAACAATCTCGCTAGAA
GTTTGCAAGGTAAATCAACCCAACTCATTGGGCTTATCTTCCCCAACATTAGCAATATCTTTTACGCTGAATTAATTGAA
CATTTGGAAATTGAATTGTTTAAACAGGGCTACAAAACTATTATTTGCAATAGTGAACATAATCCCGTCAAAGAACGCGA
ATATTTAGAAATGCTTGCGGCCAATCAAGTGGACGGCATTATTTCTTCCAGTCATAATTTGGGAATTGAGGATTATGAGC
GTGTCGAAGCTCCTATTGTAGCTTTTGACCGTAATCTAGCGCCAAATATCCCGGTTATTTCTTCAGATAATTTTGAAGGT
GGTAAATTAGCCGCACAAACTTTGCAAAAACACGGTTGTCAAAACATTGTCATGATTACAGGTAATGACAATTCTGATTC
GCCCACAGGGTTGCGCCAGCTAGGGTTTAACTACCAGCTCAAACGAAGTGCAGAAATCATCAAATTACCAAATAACCTAT
CTCCTGTTAGACGCGAAATGGAAATTAAATCCATTTTGGCAACCCGAAAACCTGATGGCCTTTTCGTTTCTGATGATTTA
ACTGCTATCCTCATTATGAAAGTAGCCAAACAACTTCACATTACTATTCCAGAGGATATGAAAGTCATAGGTTATGATGG
AACGACATTTATCCAGCAATATGTTCCTCAATTAGCGACCATTCGTCAACCTATTGATGAGATTGCTAAATTGAGTGTCG
AAATACTCATCAAAAAAATTAAAAAAGAAAAAACCAGTAAAGACTATATTTTACCGATTACGCTACTTCCAGGAGCAAGT
ATTTAA

Upstream 100 bases:

>100_bases
GTCCTAACTAGTCGGGTTTTCCCAACCCACGGACAAACAGGTATCCAAGTAGTAGAAGGACAAGCTTTTGGACATTATTA
TGAAATGAGGTATTAGGCAA

Downstream 100 bases:

>100_bases
ACAAAACATAACCAATCACTAATTACTCTAAAAGACAAACAAGCTTACTCTTTCTAGATGCGAGAGTATGCTTGTTTGTC
TTTTAATATTCGTACATAAA

Product: putative sucrose operon repressor

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIE
HLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDL
TAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGAS
I

Sequences:

>Translated_321_residues
MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIE
HLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDL
TAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGAS
I
>Mature_321_residues
MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIE
HLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDL
TAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGAS
I

Specific function: Negative regulator of scrB expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=316, Percent_Identity=33.2278481012658, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787948, Length=312, Percent_Identity=30.1282051282051, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789068, Length=301, Percent_Identity=29.5681063122924, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1790369, Length=312, Percent_Identity=26.9230769230769, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI48994940, Length=334, Percent_Identity=26.3473053892216, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786540, Length=329, Percent_Identity=27.6595744680851, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786268, Length=320, Percent_Identity=29.375, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790715, Length=314, Percent_Identity=23.8853503184713, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=28.5234899328859, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=24.7619047619048, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787906, Length=184, Percent_Identity=30.4347826086957, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790689, Length=315, Percent_Identity=23.4920634920635, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35683; Mature: 35683

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMRELGYKPNNLARSLQGKST
CCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
QLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGI
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
ISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEGGKLAAQTLQKHGCQNIVMIT
HCCCCCCCCHHHHHHCCCEEEECCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEE
GNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDL
CCCCCCCCHHHHHHCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCCH
TAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIKKI
HHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEKTSKDYILPITLLPGASI
HHHCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMRELGYKPNNLARSLQGKST
CCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
QLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGI
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
ISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEGGKLAAQTLQKHGCQNIVMIT
HCCCCCCCCHHHHHHCCCEEEECCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEEE
GNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDL
CCCCCCCCHHHHHHCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCCH
TAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIKKI
HHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEKTSKDYILPITLLPGASI
HHHCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9673256; 12397186 [H]