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The map label for this gene is vanYB [H]

Identifier: 15675610

GI number: 15675610

Start: 1461651

End: 1462394

Strand: Reverse

Name: vanYB [H]

Synonym: SPy_1765

Alternate gene names: 15675610

Gene position: 1462394-1461651 (Counterclockwise)

Preceding gene: 15675611

Following gene: 15675609

Centisome position: 78.94

GC content: 39.65

Gene sequence:

>744_bases
ATGAAATATAATTCGTTAAACTATTTAGTGCAATTGCTAATTGTTATTGTTTTTTTAGGAGGGCTTTACCTCTTTATAAA
ACCAGAAGAGTCAGTAACACCAACTCAGTTGAATAAAAAAGAAATCCAACAAAAAGATATCAAAAAAACGGACCGTTTAC
GAGCTTTACCTAAGGTATCTGTTGAAGATTGGGAGTTGGTTTTAGTAAACCGCGATCACATTACAAAAGAAATGAGTCCT
GAATTAGCTGACATTAATGGTATTTCTGTGGATAAACGCATTGAGCAAGCCACTAGTGACTTTTTAGCAGCAGCACAAGC
TATCGACTTGCAAGAACATCTTATCTCTGGGTACCGTTCCGTAGACTACCAAACAGAGCTTTACCAATCTTATATTAAAA
AAGAGATGGCTAACGATCCAACATTGACACAAGAAGCTGCGGAGGCTTTGGTGCAAACCTATTCACAGCCGCCAGGGGCT
AGTGAACATCACACTGGTCTTGCTATTGACATGAGCACTGTAGATACTTTAAATGCCAGTGATCCATCAGTAGCTAAAGC
AGTTCAAAAAATTGCACCTGATTATGGGTTTGTCTTGCGCTTTCCAGAAGGAAAAAAGACTAGTACAGGGGTTGATTATG
AGGATTGGCATTACCGCTATGTAGGCAAGGCGTCTGCTCGTTATATGGCTCAGCACAACCTAACGTTGGAAGAGTACATT
GCTGCTTTAAAGGAGAAACGATGA

Upstream 100 bases:

>100_bases
GTTACAGTTGTTGAATTTGATGATGGCCAATTTACGATAAAGACTATTGGAGATATGAGTTACCGCTACCGCGGTCGTGA
AATAATAGAAGAACGGTCAG

Downstream 100 bases:

>100_bases
GAAAACGACTAAAGTTTCCGTATTTTTTAACGCTTCTAGCTTGCTTTTTATTGCTGATTGTTTGTCCCTTACTGAGTAGC
CAAAGGATAGCTAGTGCAGA

Product: putative D,D-carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQKDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSP
ELADINGISVDKRIEQATSDFLAAAQAIDLQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGA
SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYI
AALKEKR

Sequences:

>Translated_247_residues
MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQKDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSP
ELADINGISVDKRIEQATSDFLAAAQAIDLQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGA
SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYI
AALKEKR
>Mature_247_residues
MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQKDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSP
ELADINGISVDKRIEQATSDFLAAAQAIDLQEHLISGYRSVDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGA
SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYI
AALKEKR

Specific function: Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams [H]

COG id: COG1876

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR003709 [H]

Pfam domain/function: PF02557 VanY [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 27959; Mature: 27959

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQKDIKKTDRLRALPKVS
CCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
VEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFLAAAQAIDLQEHLISGYRS
CCCEEEEEECCHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGASEHHTGLAIDMSTVDTLNAS
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHCCCCCC
DPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYI
CHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCHHHHH
AALKEKR
HHHHCCC
>Mature Secondary Structure
MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQKDIKKTDRLRALPKVS
CCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
VEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFLAAAQAIDLQEHLISGYRS
CCCEEEEEECCHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VDYQTELYQSYIKKEMANDPTLTQEAAEALVQTYSQPPGASEHHTGLAIDMSTVDTLNAS
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHCCCCCC
DPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHYRYVGKASARYMAQHNLTLEEYI
CHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCCHHHHH
AALKEKR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8631706; 12663927 [H]